Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 20 of 67


Human Keratinocytes Respond to Extracellular UTP by Induction of Hyaluronan Synthase 2 Expression and Increased Hyaluronan Synthesis.

Jokela TA, Kärnä R, Rauhala L, Bart G, Pasonen-Seppänen S, Oikari S, Tammi MI, Tammi RH.

J Biol Chem. 2017 Feb 10. pii: jbc.M116.760322. doi: 10.1074/jbc.M116.760322. [Epub ahead of print]


Hexosamine biosynthesis in keratinocytes: roles of GFAT and GNPDA enzymes in the maintenance of UDP-GlcNAc content and hyaluronan synthesis.

Oikari S, Makkonen K, Deen AJ, Tyni I, Kärnä R, Tammi RH, Tammi MI.

Glycobiology. 2016 Jul;26(7):710-22. doi: 10.1093/glycob/cww019.


Fluorescence resonance energy transfer (FRET) and proximity ligation assays reveal functionally relevant homo- and heteromeric complexes among hyaluronan synthases HAS1, HAS2, and HAS3.

Bart G, Vico NO, Hassinen A, Pujol FM, Deen AJ, Ruusala A, Tammi RH, Squire A, Heldin P, Kellokumpu S, Tammi MI.

J Biol Chem. 2015 May 1;290(18):11479-90. doi: 10.1074/jbc.M115.640581.


Decreased hyaluronidase 1 expression is associated with early disease recurrence in human endometrial cancer.

Nykopp TK, Pasonen-Seppänen S, Tammi MI, Tammi RH, Kosma VM, Anttila M, Sironen R.

Gynecol Oncol. 2015 Apr;137(1):152-9. doi: 10.1016/j.ygyno.2015.01.525.


Isothiocyanate analogs targeting CD44 receptor as an effective strategy against colon cancer.

Misra S, Ghatak S, Vyas A, O'Brien P, Markwald RR, Khetmalas M, Hascall VC, McCarthy JB, Karamanos NK, Tammi MI, Tammi RH, Prestwitch GD, Padhye S.

Med Chem Res. 2014 Aug 1;23(8):3836-3851.


rClca2 is associated with epidermal differentiation and is strongly downregulated by ultraviolet radiation.

Bart G, Hämäläinen L, Rauhala L, Salonen P, Kokkonen M, Dunlop TW, Pehkonen P, Kumlin T, Tammi MI, Pasonen-Seppänen S, Tammi RH.

Br J Dermatol. 2014 Aug;171(2):376-87. doi: 10.1111/bjd.13038.


Rab10-mediated endocytosis of the hyaluronan synthase HAS3 regulates hyaluronan synthesis and cell adhesion to collagen.

Deen AJ, Rilla K, Oikari S, Kärnä R, Bart G, Häyrinen J, Bathina AR, Ropponen A, Makkonen K, Tammi RH, Tammi MI.

J Biol Chem. 2014 Mar 21;289(12):8375-89. doi: 10.1074/jbc.M114.552133.


OGT and OGA expression in postmenopausal skeletal muscle associates with hormone replacement therapy and muscle cross-sectional area.

Toivonen MH, Pöllänen E, Ahtiainen M, Suominen H, Taaffe DR, Cheng S, Takala T, Kujala UM, Tammi MI, Sipilä S, Kovanen V.

Exp Gerontol. 2013 Dec;48(12):1501-4. doi: 10.1016/j.exger.2013.10.007.


Hyaluronan synthase 1 (HAS1) produces a cytokine-and glucose-inducible, CD44-dependent cell surface coat.

Siiskonen H, Kärnä R, Hyttinen JM, Tammi RH, Tammi MI, Rilla K.

Exp Cell Res. 2014 Jan 1;320(1):153-63. doi: 10.1016/j.yexcr.2013.09.021.


Hyaluronan production enhances shedding of plasma membrane-derived microvesicles.

Rilla K, Pasonen-Seppänen S, Deen AJ, Koistinen VV, Wojciechowski S, Oikari S, Kärnä R, Bart G, Törrönen K, Tammi RH, Tammi MI.

Exp Cell Res. 2013 Aug 1;319(13):2006-18. doi: 10.1016/j.yexcr.2013.05.021.


Mannose reduces hyaluronan and leukocytes in wound granulation tissue and inhibits migration and hyaluronan-dependent monocyte binding.

Jokela TA, Kuokkanen J, Kärnä R, Pasonen-Seppänen S, Rilla K, Kössi J, Laato M, Tammi RH, Tammi MI.

Wound Repair Regen. 2013 Mar-Apr;21(2):247-55. doi: 10.1111/wrr.12022.


Hyaluronan synthase 1 (HAS1) requires higher cellular UDP-GlcNAc concentration than HAS2 and HAS3.

Rilla K, Oikari S, Jokela TA, Hyttinen JM, Kärnä R, Tammi RH, Tammi MI.

J Biol Chem. 2013 Feb 22;288(8):5973-83. doi: 10.1074/jbc.M112.443879.


Hyaluronan in cytosol--microinjection-based probing of its existence and suggested functions.

Siiskonen H, Rilla K, Kärnä R, Bart G, Jing W, Haller MF, DeAngelis PL, Tammi RH, Tammi MI.

Glycobiology. 2013 Feb;23(2):222-31. doi: 10.1093/glycob/cws149.


Synthesis and fragmentation of hyaluronan in renal ischaemia.

Declèves AE, Caron N, Voisin V, Legrand A, Bouby N, Kultti A, Tammi MI, Flamion B.

Nephrol Dial Transplant. 2012 Oct;27(10):3771-81. doi: 10.1093/ndt/gfs098.


HAS3-induced accumulation of hyaluronan in 3D MDCK cultures results in mitotic spindle misorientation and disturbed organization of epithelium.

Rilla K, Pasonen-Seppänen S, Kärnä R, Karjalainen HM, Törrönen K, Koistinen V, Tammi MI, Tammi RH, Teräväinen T, Manninen A.

Histochem Cell Biol. 2012 Feb;137(2):153-64. doi: 10.1007/s00418-011-0896-x.


Chronic UVR causes increased immunostaining of CD44 and accumulation of hyaluronan in mouse epidermis.

Siiskonen H, Törrönen K, Kumlin T, Rilla K, Tammi MI, Tammi RH.

J Histochem Cytochem. 2011 Oct;59(10):908-17. doi: 10.1369/0022155411417874.


Cellular content of UDP-N-acetylhexosamines controls hyaluronan synthase 2 expression and correlates with O-linked N-acetylglucosamine modification of transcription factors YY1 and SP1.

Jokela TA, Makkonen KM, Oikari S, Kärnä R, Koli E, Hart GW, Tammi RH, Carlberg C, Tammi MI.

J Biol Chem. 2011 Sep 23;286(38):33632-40. doi: 10.1074/jbc.M111.265637.


Transcriptional and post-translational regulation of hyaluronan synthesis.

Tammi RH, Passi AG, Rilla K, Karousou E, Vigetti D, Makkonen K, Tammi MI.

FEBS J. 2011 May;278(9):1419-28. doi: 10.1111/j.1742-4658.2011.08070.x. Review.


Hyaluronan synthases (HAS1-3) and hyaluronidases (HYAL1-2) in the accumulation of hyaluronan in endometrioid endometrial carcinoma.

Nykopp TK, Rilla K, Tammi MI, Tammi RH, Sironen R, Hämäläinen K, Kosma VM, Heinonen S, Anttila M.

BMC Cancer. 2010 Sep 27;10:512. doi: 10.1186/1471-2407-10-512.

Supplemental Content

Loading ...
Support Center