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Items: 1 to 20 of 22

1.

Novel concept to guide systolic heart failure medication by repeated biomarker testing-results from TIME-CHF in context of predictive, preventive, and personalized medicine.

Davarzani N, Sanders-van Wijk S, Maeder MT, Rickenbacher P, Smirnov E, Karel J, Suter T, de Boer RA, Block D, Rolny V, Zaugg C, Pfisterer ME, Peeters R, Brunner-La Rocca HP; TIME-CHF investigators.

EPMA J. 2018 May 13;9(2):161-173. doi: 10.1007/s13167-018-0137-7. eCollection 2018 Jun.

2.

Heart failure with mid-range ejection fraction: a distinct clinical entity? Insights from the Trial of Intensified versus standard Medical therapy in Elderly patients with Congestive Heart Failure (TIME-CHF).

Rickenbacher P, Kaufmann BA, Maeder MT, Bernheim A, Goetschalckx K, Pfister O, Pfisterer M, Brunner-La Rocca HP; TIME-CHF Investigators.

Eur J Heart Fail. 2017 Dec;19(12):1586-1596. doi: 10.1002/ejhf.798. Epub 2017 Mar 15.

PMID:
28295985
3.

Predicting hospitalization and mortality in patients with heart failure: The BARDICHE-index.

Uszko-Lencer NHMK, Frankenstein L, Spruit MA, Maeder MT, Gutmann M, Muzzarelli S, Osswald S, Pfisterer ME, Zugck C, Brunner-La Rocca HP; TIME-CHF Investigators.

Int J Cardiol. 2017 Jan 15;227:901-907. doi: 10.1016/j.ijcard.2016.11.122. Epub 2016 Nov 9.

PMID:
27915084
4.

Prognostic Value of the Change in Heart Rate From the Supine to the Upright Position in Patients With Chronic Heart Failure.

Maeder MT, Zurek M, Rickli H, Tobler D, Kiencke S, Suter T, Yoon SI, Julius B, Pfisterer ME, Brunner-La Rocca HP; TIME‐CHF Investigators.

J Am Heart Assoc. 2016 Aug 8;5(8). pii: e003524. doi: 10.1161/JAHA.116.003524.

5.

Circulating biomarkers of distinct pathophysiological pathways in heart failure with preserved vs. reduced left ventricular ejection fraction.

Sanders-van Wijk S, van Empel V, Davarzani N, Maeder MT, Handschin R, Pfisterer ME, Brunner-La Rocca HP; TIME-CHF investigators.

Eur J Heart Fail. 2015 Oct;17(10):1006-14. doi: 10.1002/ejhf.414. Epub 2015 Oct 16.

6.

Improvement in left ventricular ejection fraction and reverse remodeling in elderly heart failure patients on intense NT-proBNP-guided therapy.

Kaufmann BA, Goetschalckx K, Min SY, Maeder MT, Bucher U, Nietlispach F, Bernheim AM, Pfisterer ME, Brunner-La Rocca HP; TIME-CHF investigators.

Int J Cardiol. 2015 Jul 15;191:286-93. doi: 10.1016/j.ijcard.2015.04.282. Epub 2015 May 2.

PMID:
25981371
7.

Impact of worsening renal function related to medication in heart failure.

Brunner-La Rocca HP, Knackstedt C, Eurlings L, Rolny V, Krause F, Pfisterer ME, Tobler D, Rickenbacher P, Maeder MT; TIME‐CHF investigators.

Eur J Heart Fail. 2015 Feb;17(2):159-68. doi: 10.1002/ejhf.210. Epub 2014 Dec 30.

8.

Differential prognostic impact of resting heart rate in older compared with younger patients with chronic heart failure--insights from TIME-CHF.

Zurek M, Maeder MT, Rickli H, Muzzarelli S, Sanders-van Wijk S, Abbühl H, Handschin R, Jeker U, Pfisterer M, Brunner-la Rocca HP; TIME-CHF Investigators.

J Card Fail. 2015 Apr;21(4):347-54. doi: 10.1016/j.cardfail.2014.12.014. Epub 2015 Jan 7.

PMID:
25576682
9.

Cost-effectiveness of N-terminal pro-B-type natriuretic-guided therapy in elderly heart failure patients: results from TIME-CHF (Trial of Intensified versus Standard Medical Therapy in Elderly Patients with Congestive Heart Failure).

Sanders-van Wijk S, van Asselt AD, Rickli H, Estlinbaum W, Erne P, Rickenbacher P, Vuillomenet A, Peter M, Pfisterer ME, Brunner-La Rocca HP; TIME-CHF Investigators.

JACC Heart Fail. 2013 Feb;1(1):64-71. doi: 10.1016/j.jchf.2012.08.002. Epub 2013 Feb 4.

10.

Long-term results of intensified, N-terminal-pro-B-type natriuretic peptide-guided versus symptom-guided treatment in elderly patients with heart failure: five-year follow-up from TIME-CHF.

Sanders-van Wijk S, Maeder MT, Nietlispach F, Rickli H, Estlinbaum W, Erne P, Rickenbacher P, Peter M, Pfisterer MP, Brunner-La Rocca HP; TIME-CHF Investigators.

Circ Heart Fail. 2014 Jan;7(1):131-9. doi: 10.1161/CIRCHEARTFAILURE.113.000527. Epub 2013 Dec 18.

11.

Prognostic impact of systemic inflammatory diseases in elderly patients with congestive heart failure.

Burkard T, Pfister O, Rickli H, Follath F, Hack D, Zaker R, Pittl U, Handschin R, Pfisterer M, Brunner-La Rocca HP; Time-CHF Investigators.

QJM. 2014 Feb;107(2):131-8. doi: 10.1093/qjmed/hct205. Epub 2013 Oct 15.

PMID:
24131549
12.

Safety and tolerability of intensified, N-terminal pro brain natriuretic peptide-guided compared with standard medical therapy in elderly patients with congestive heart failure: results from TIME-CHF.

Sanders-van Wijk S, Muzzarelli S, Neuhaus M, Kiencke S, Maeder M, Estlinbaum W, Tobler D, Mayer K, Erne P, Pfisterer ME, Brunner-La Rocca HP; TIME-CHF investigators.

Eur J Heart Fail. 2013 Aug;15(8):910-8. doi: 10.1093/eurjhf/hft079. Epub 2013 May 10.

13.

N-terminal pro brain natriuretic peptide-guided management in patients with heart failure and preserved ejection fraction: findings from the Trial of Intensified versus standard medical therapy in elderly patients with congestive heart failure (TIME-CHF).

Maeder MT, Rickenbacher P, Rickli H, Abbühl H, Gutmann M, Erne P, Vuilliomenet A, Peter M, Pfisterer M, Brunner-La Rocca HP; TIME-CHF Investigators.

Eur J Heart Fail. 2013 Oct;15(10):1148-56. doi: 10.1093/eurjhf/hft076. Epub 2013 May 8.

14.

Cognitive impairment in heart failure: results from the Trial of Intensified versus standard Medical therapy in Elderly patients with Congestive Heart Failure (TIME-CHF) randomized trial.

Huijts M, van Oostenbrugge RJ, Duits A, Burkard T, Muzzarelli S, Maeder MT, Schindler R, Pfisterer ME, Brunner-La Rocca HP; TIME-CHF Investigators.

Eur J Heart Fail. 2013 Jun;15(6):699-707. doi: 10.1093/eurjhf/hft020. Epub 2013 Feb 5.

15.

Prognostic value of self-reported versus objectively measured functional capacity in patients with heart failure: results from the TIME-CHF (Trial of Intensified Versus Standard Medical Therapy in Elderly Patients with Congestive Heart Failure).

Spruit MA, Maeder MT, Knackstedt C, Ammann P, Jeker U, Uszko-Lencer NH, Kiencke S, Pfisterer ME, Rickli H, Brunner-La Rocca HP; TIME-CHF Investigators.

J Am Coll Cardiol. 2012 Nov 13;60(20):2125-6. doi: 10.1016/j.jacc.2012.08.968. No abstract available.

16.

Why and how do elderly patients with heart failure die? Insights from the TIME-CHF study.

Rickenbacher P, Pfisterer M, Burkard T, Kiowski W, Follath F, Burckhardt D, Schindler R, Brunner-La Rocca HP; TIME-CHF Investigators.

Eur J Heart Fail. 2012 Nov;14(11):1218-29. doi: 10.1093/eurjhf/hfs113. Epub 2012 Jul 6.

17.

Incidence, clinical predictors, and prognostic impact of worsening renal function in elderly patients with chronic heart failure on intensive medical therapy.

Maeder MT, Rickli H, Pfisterer ME, Muzzarelli S, Ammann P, Fehr T, Hack D, Weilenmann D, Dieterle T, Kiencke S, Estlinbaum W, Brunner-La Rocca HP; TIME-CHF Investigators.

Am Heart J. 2012 Mar;163(3):407-14, 414.e1. doi: 10.1016/j.ahj.2011.12.003.

PMID:
22424011
18.

Frequency and predictors of hyperkalemia in patients ≥60 years of age with heart failure undergoing intense medical therapy.

Muzzarelli S, Maeder MT, Toggweiler S, Rickli H, Nietlispach F, Julius B, Burkard T, Pfisterer ME, Brunner-La Rocca HP; TIME-CHF Investigators.

Am J Cardiol. 2012 Mar 1;109(5):693-8. doi: 10.1016/j.amjcard.2011.10.027. Epub 2011 Dec 5.

PMID:
22152974
19.

End-of-life preferences of elderly patients with chronic heart failure.

Brunner-La Rocca HP, Rickenbacher P, Muzzarelli S, Schindler R, Maeder MT, Jeker U, Kiowski W, Leventhal ME, Pfister O, Osswald S, Pfisterer ME, Rickli H; TIME-CHF Investigators.

Eur Heart J. 2012 Mar;33(6):752-9. doi: 10.1093/eurheartj/ehr404. Epub 2011 Nov 8.

PMID:
22067089
20.

Predictors of early readmission or death in elderly patients with heart failure.

Muzzarelli S, Leibundgut G, Maeder MT, Rickli H, Handschin R, Gutmann M, Jeker U, Buser P, Pfisterer M, Brunner-La Rocca HP; TIME-CHF Investigators.

Am Heart J. 2010 Aug;160(2):308-14. doi: 10.1016/j.ahj.2010.05.007.

PMID:
20691837

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