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Items: 1 to 20 of 110


Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry.

Zhang F, Wei K, Slowikowski K, Fonseka CY, Rao DA, Kelly S, Goodman SM, Tabechian D, Hughes LB, Salomon-Escoto K, Watts GFM, Jonsson AH, Rangel-Moreno J, Meednu N, Rozo C, Apruzzese W, Eisenhaure TM, Lieb DJ, Boyle DL, Mandelin AM 2nd; Accelerating Medicines Partnership Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Consortium, Boyce BF, DiCarlo E, Gravallese EM, Gregersen PK, Moreland L, Firestein GS, Hacohen N, Nusbaum C, Lederer JA, Perlman H, Pitzalis C, Filer A, Holers VM, Bykerk VP, Donlin LT, Anolik JH, Brenner MB, Raychaudhuri S.

Nat Immunol. 2019 May 6. doi: 10.1038/s41590-019-0378-1. [Epub ahead of print]


Microglial activation in an amyotrophic lateral sclerosis-like model caused by Ranbp2 loss and nucleocytoplasmic transport impairment in retinal ganglion neurons.

Cho KI, Yoon D, Yu M, Peachey NS, Ferreira PA.

Cell Mol Life Sci. 2019 Apr 3. doi: 10.1007/s00018-019-03078-5. [Epub ahead of print]


Suppressor of Cytokine Signaling-1/STAT1 Regulates Renal Inflammation in Mesangial Proliferative Glomerulonephritis Models.

Bai J, Wu L, Chen X, Wang L, Li Q, Zhang Y, Wu J, Cai G, Chen X.

Front Immunol. 2018 Aug 30;9:1982. doi: 10.3389/fimmu.2018.01982. eCollection 2018.


Microdose Lithium NP03 Diminishes Pre-Plaque Oxidative Damage and Neuroinflammation in a Rat Model of Alzheimer's-like Amyloidosis.

Wilson EN, Do Carmo S, Iulita MF, Hall H, Austin GL, Jia DT, Malcolm JC, Foret MK, Marks AR, Butterfield DA, Cuello AC.

Curr Alzheimer Res. 2018;15(13):1220-1230. doi: 10.2174/1567205015666180904154446.


Foxc1 promotes the proliferation of fibroblast-like synoviocytes in rheumatoid arthritis via PI3K/AKT signalling pathway.

Yu Z, Xu H, Wang H, Wang Y.

Tissue Cell. 2018 Aug;53:15-22. doi: 10.1016/j.tice.2018.05.011. Epub 2018 May 22.


A Profibrotic Phenotype in Naïve and in Fibrotic Lung Myofibroblasts Is Governed by Modulations in Thy-1 Expression and Activation.

Cohen PY, Breuer R, Wallach-Dayan SB.

Mediators Inflamm. 2018 May 29;2018:4638437. doi: 10.1155/2018/4638437. eCollection 2018.


Innate Recognition of the Microbiota by TLR1 Promotes Epithelial Homeostasis and Prevents Chronic Inflammation.

Kamdar K, Johnson AMF, Chac D, Myers K, Kulur V, Truevillian K, DePaolo RW.

J Immunol. 2018 Jul 1;201(1):230-242. doi: 10.4049/jimmunol.1701216. Epub 2018 May 23.


Chronic Hippocampal Expression of Notch Intracellular Domain Induces Vascular Thickening, Reduces Glucose Availability, and Exacerbates Spatial Memory Deficits in a Rat Model of Early Alzheimer.

Galeano P, Leal MC, Ferrari CC, Dalmasso MC, Martino Adami PV, Farías MI, Casabona JC, Puntel M, Do Carmo S, Smal C, Arán M, Castaño EM, Pitossi FJ, Cuello AC, Morelli L.

Mol Neurobiol. 2018 Nov;55(11):8637-8650. doi: 10.1007/s12035-018-1002-3. Epub 2018 Mar 26.


The role of transcriptional factor D-site-binding protein in circadian CCL2 gene expression in anti-Thy1 nephritis.

Lu Y, Mei Y, Chen L, Wu L, Wang X, Zhang Y, Fu B, Chen X, Xie Y, Cai G, Bai X, Li Q, Chen X.

Cell Mol Immunol. 2018 Mar 22. doi: 10.1038/s41423-018-0020-4. [Epub ahead of print]


Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis.

Mizoguchi F, Slowikowski K, Wei K, Marshall JL, Rao DA, Chang SK, Nguyen HN, Noss EH, Turner JD, Earp BE, Blazar PE, Wright J, Simmons BP, Donlin LT, Kalliolias GD, Goodman SM, Bykerk VP, Ivashkiv LB, Lederer JA, Hacohen N, Nigrovic PA, Filer A, Buckley CD, Raychaudhuri S, Brenner MB.

Nat Commun. 2018 Feb 23;9(1):789. doi: 10.1038/s41467-018-02892-y.


Fibrinogen cleavage products and Toll-like receptor 4 promote the generation of programmed cell death 1 ligand 2-positive dendritic cells in allergic asthma.

Cho M, Lee JE, Lim H, Shin HW, Khalmuratova R, Choi G, Kim HS, Choi WS, Park YJ, Shim I, Kim BS, Kang CY, Kim JO, Tanaka S, Kubo M, Tung HY, Landers CT, Corry DB, Kheradmand F, Chung Y.

J Allergy Clin Immunol. 2018 Aug;142(2):530-541.e6. doi: 10.1016/j.jaci.2017.09.019. Epub 2017 Oct 14.


Targeted delivery of celastrol to mesangial cells is effective against mesangioproliferative glomerulonephritis.

Guo L, Luo S, Du Z, Zhou M, Li P, Fu Y, Sun X, Huang Y, Zhang Z.

Nat Commun. 2017 Oct 12;8(1):878. doi: 10.1038/s41467-017-00834-8.


Selection of optimal molecular targets for tumor-specific imaging in pancreatic ductal adenocarcinoma.

Tummers WS, Farina-Sarasqueta A, Boonstra MC, Prevoo HA, Sier CF, Mieog JS, Morreau J, van Eijck CH, Kuppen PJ, van de Velde CJ, Bonsing BA, Vahrmeijer AL, Swijnenburg RJ.

Oncotarget. 2017 May 26;8(34):56816-56828. doi: 10.18632/oncotarget.18232. eCollection 2017 Aug 22.


Thy1 (CD90) Expression Is Elevated in Radiation-Induced Periprosthetic Capsular Contracture: Implication for Novel Therapeutics.

Hansen TC, Woeller CF, Lacy SH, Koltz PF, Langstein HN, Phipps RP.

Plast Reconstr Surg. 2017 Aug;140(2):316-326. doi: 10.1097/PRS.0000000000003542.


Voluntary Exercise Promotes Glymphatic Clearance of Amyloid Beta and Reduces the Activation of Astrocytes and Microglia in Aged Mice.

He XF, Liu DX, Zhang Q, Liang FY, Dai GY, Zeng JS, Pei Z, Xu GQ, Lan Y.

Front Mol Neurosci. 2017 May 19;10:144. doi: 10.3389/fnmol.2017.00144. eCollection 2017.


Epigenetic intervention with a BET inhibitor ameliorates acute retinal ganglion cell death in mice.

Li J, Zhao L, Urabe G, Fu Y, Guo LW.

Mol Vis. 2017 Mar 21;23:149-159. eCollection 2017.


Worsening of memory deficit induced by energy-dense diet in a rat model of early-Alzheimer's disease is associated to neurotoxic Aβ species and independent of neuroinflammation.

Martino Adami PV, Galeano P, Wallinger ML, Quijano C, Rabossi A, Pagano ES, Olivar N, Reyes Toso C, Cardinali D, Brusco LI, Do Carmo S, Radi R, Gevorkian G, Castaño EM, Cuello AC, Morelli L.

Biochim Biophys Acta Mol Basis Dis. 2017 Mar;1863(3):731-743. doi: 10.1016/j.bbadis.2016.12.014. Epub 2016 Dec 27.


T-bet inhibits innate lymphoid cell-mediated eosinophilic airway inflammation by suppressing IL-9 production.

Matsuki A, Takatori H, Makita S, Yokota M, Tamachi T, Suto A, Suzuki K, Hirose K, Nakajima H.

J Allergy Clin Immunol. 2017 Apr;139(4):1355-1367.e6. doi: 10.1016/j.jaci.2016.08.022. Epub 2016 Sep 23.


Increased pulmonary arteriolar tone associated with lung oxidative stress and nitric oxide in a mouse model of Alzheimer's disease.

Roberts AM, Jagadapillai R, Vaishnav RA, Friedland RP, Drinovac R, Lin X, Gozal E.

Physiol Rep. 2016 Sep;4(17). pii: e12953. doi: 10.14814/phy2.12953.


IL-17 Expression in the Time Course of Acute Anti-Thy1 Glomerulonephritis.

Loof T, Krämer S, Gaedeke J, Neumayer HH, Peters H.

PLoS One. 2016 May 31;11(5):e0156480. doi: 10.1371/journal.pone.0156480. eCollection 2016.

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