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Items: 3

1.

Plecanatide and dolcanatide, novel guanylate cyclase-C agonists, ameliorate gastrointestinal inflammation in experimental models of murine colitis.

Shailubhai K, Palejwala V, Arjunan KP, Saykhedkar S, Nefsky B, Foss JA, Comiskey S, Jacob GS, Plevy SE.

World J Gastrointest Pharmacol Ther. 2015 Nov 6;6(4):213-22. doi: 10.4292/wjgpt.v6.i4.213.

2.

Plecanatide, an oral guanylate cyclase C agonist acting locally in the gastrointestinal tract, is safe and well-tolerated in single doses.

Shailubhai K, Comiskey S, Foss JA, Feng R, Barrow L, Comer GM, Jacob GS.

Dig Dis Sci. 2013 Sep;58(9):2580-6. doi: 10.1007/s10620-013-2684-z. Epub 2013 Apr 27.

PMID:
23625291
3.

Therapeutic applications of guanylate cyclase-C receptor agonists.

Shailubhai K.

Curr Opin Drug Discov Devel. 2002 Mar;5(2):261-8. Review.

PMID:
11926132

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