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Items: 1 to 20 of 26


Distinct chromatin functional states correlate with HIV latency reactivation in infected primary CD4+ T cells.

Battivelli E, Dahabieh MS, Abdel-Mohsen M, Svensson JP, Tojal Da Silva I, Cohn LB, Gramatica A, Deeks S, Greene WC, Pillai SK, Verdin E.

Elife. 2018 May 1;7. pii: e34655. doi: 10.7554/eLife.34655.


The mTOR Complex Controls HIV Latency.

Besnard E, Hakre S, Kampmann M, Lim HW, Hosmane NN, Martin A, Bassik MC, Verschueren E, Battivelli E, Chan J, Svensson JP, Gramatica A, Conrad RJ, Ott M, Greene WC, Krogan NJ, Siliciano RF, Weissman JS, Verdin E.

Cell Host Microbe. 2016 Dec 14;20(6):785-797. doi: 10.1016/j.chom.2016.11.001.


The Paf1 complex factors Leo1 and Paf1 promote local histone turnover to modulate chromatin states in fission yeast.

Sadeghi L, Prasad P, Ekwall K, Cohen A, Svensson JP.

EMBO Rep. 2015 Dec;16(12):1673-87. doi: 10.15252/embr.201541214. Epub 2015 Oct 29.


PARP1- and CTCF-Mediated Interactions between Active and Repressed Chromatin at the Lamina Promote Oscillating Transcription.

Zhao H, Sifakis EG, Sumida N, Millán-Ariño L, Scholz BA, Svensson JP, Chen X, Ronnegren AL, Mallet de Lima CD, Varnoosfaderani FS, Shi C, Loseva O, Yammine S, Israelsson M, Rathje LS, Németi B, Fredlund E, Helleday T, Imreh MP, Göndör A.

Mol Cell. 2015 Sep 17;59(6):984-97. doi: 10.1016/j.molcel.2015.07.019. Epub 2015 Aug 27.


A nucleosome turnover map reveals that the stability of histone H4 Lys20 methylation depends on histone recycling in transcribed chromatin.

Svensson JP, Shukla M, Menendez-Benito V, Norman-Axelsson U, Audergon P, Sinha I, Tanny JC, Allshire RC, Ekwall K.

Genome Res. 2015 Jun;25(6):872-83. doi: 10.1101/gr.188870.114. Epub 2015 Mar 16.


Epigenetic activation and inactivation of centromeres.

Svensson JP, Ekwall K.

Epigenomics. 2014;6(5):451-4. doi: 10.2217/epi.14.33. No abstract available.


Centromeric histone H2B monoubiquitination promotes noncoding transcription and chromatin integrity.

Sadeghi L, Siggens L, Svensson JP, Ekwall K.

Nat Struct Mol Biol. 2014 Mar;21(3):236-43. doi: 10.1038/nsmb.2776. Epub 2014 Feb 16.


Genomic phenotyping by barcode sequencing broadly distinguishes between alkylating agents, oxidizing agents, and non-genotoxic agents, and reveals a role for aromatic amino acids in cellular recovery after quinone exposure.

Svensson JP, Quirós Pesudo L, McRee SK, Adeleye Y, Carmichael P, Samson LD.

PLoS One. 2013 Sep 9;8(9):e73736. doi: 10.1371/journal.pone.0073736. eCollection 2013.


Microfluidic genome-wide profiling of intrinsic electrical properties in Saccharomyces cerevisiae.

Vahey MD, Quiros Pesudo L, Svensson JP, Samson LD, Voldman J.

Lab Chip. 2013 Jul 21;13(14):2754-63. doi: 10.1039/c3lc50162k.


CHD1 remodelers regulate nucleosome spacing in vitro and align nucleosomal arrays over gene coding regions in S. pombe.

Pointner J, Persson J, Prasad P, Norman-Axelsson U, Strålfors A, Khorosjutina O, Krietenstein N, Svensson JP, Ekwall K, Korber P.

EMBO J. 2012 Nov 28;31(23):4388-403. doi: 10.1038/emboj.2012.289. Epub 2012 Oct 26.


Factors that promote H3 chromatin integrity during transcription prevent promiscuous deposition of CENP-A(Cnp1) in fission yeast.

Choi ES, Strålfors A, Catania S, Castillo AG, Svensson JP, Pidoux AL, Ekwall K, Allshire RC.

PLoS Genet. 2012 Sep;8(9):e1002985. doi: 10.1371/journal.pgen.1002985. Epub 2012 Sep 20.


Hierarchical modularity and the evolution of genetic interactomes across species.

Ryan CJ, Roguev A, Patrick K, Xu J, Jahari H, Tong Z, Beltrao P, Shales M, Qu H, Collins SR, Kliegman JI, Jiang L, Kuo D, Tosti E, Kim HS, Edelmann W, Keogh MC, Greene D, Tang C, Cunningham P, Shokat KM, Cagney G, Svensson JP, Guthrie C, Espenshade PJ, Ideker T, Krogan NJ.

Mol Cell. 2012 Jun 8;46(5):691-704. doi: 10.1016/j.molcel.2012.05.028.


Identification of novel human damage response proteins targeted through yeast orthology.

Svensson JP, Fry RC, Wang E, Somoza LA, Samson LD.

PLoS One. 2012;7(5):e37368. doi: 10.1371/journal.pone.0037368. Epub 2012 May 16.


Genomic phenotyping of the essential and non-essential yeast genome detects novel pathways for alkylation resistance.

Svensson JP, Pesudo LQ, Fry RC, Adeleye YA, Carmichael P, Samson LD.

BMC Syst Biol. 2011 Oct 6;5:157. doi: 10.1186/1752-0509-5-157.


Podbat: a novel genomic tool reveals Swr1-independent H2A.Z incorporation at gene coding sequences through epigenetic meta-analysis.

Sadeghi L, Bonilla C, Strålfors A, Ekwall K, Svensson JP.

PLoS Comput Biol. 2011 Aug;7(8):e1002163. doi: 10.1371/journal.pcbi.1002163. Epub 2011 Aug 25.


Topoisomerases, chromatin and transcription termination.

Durand-Dubief M, Svensson JP, Persson J, Ekwall K.

Transcription. 2011 Mar;2(2):66-70.


Genomic predictors of interindividual differences in response to DNA damaging agents.

Fry RC, Svensson JP, Valiathan C, Wang E, Hogan BJ, Bhattacharya S, Bugni JM, Whittaker CA, Samson LD.

Genes Dev. 2008 Oct 1;22(19):2621-6. doi: 10.1101/gad.1688508. Epub 2008 Sep 19.


Transcriptional networks in S. cerevisiae linked to an accumulation of base excision repair intermediates.

Rusyn I, Fry RC, Begley TJ, Klapacz J, Svensson JP, Ambrose M, Samson LD.

PLoS One. 2007 Nov 28;2(11):e1252.


Activation of inflammation/NF-kappaB signaling in infants born to arsenic-exposed mothers.

Fry RC, Navasumrit P, Valiathan C, Svensson JP, Hogan BJ, Luo M, Bhattacharya S, Kandjanapa K, Soontararuks S, Nookabkaew S, Mahidol C, Ruchirawat M, Samson LD.

PLoS Genet. 2007 Nov;3(11):e207.


A portrait of cisplatin-induced transcriptional changes in mouse embryonic stem cells reveals a dominant p53-like response.

Kruse JJ, Svensson JP, Huigsloot M, Giphart-Gassler M, Schoonen WG, Polman JE, Jean Horbach G, van de Water B, Vrieling H.

Mutat Res. 2007 Apr 1;617(1-2):58-70. Epub 2007 Feb 2.


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