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A fully recombinant human IgG1 Fc multimer (GL-2045) inhibits complement-mediated cytotoxicity and induces iC3b.

Zhou H, Olsen H, So E, Mérigeon E, Rybin D, Owens J, LaRosa G, Block DS, Strome SE, Zhang X.

Blood Adv. 2017 Mar 14;1(8):504-515. doi: 10.1182/bloodadvances.2016001917. eCollection 2017 Mar 14.


Loss of the Caenorhabditis elegans pocket protein LIN-35 reveals MuvB's innate function as the repressor of DREAM target genes.

Goetsch PD, Garrigues JM, Strome S.

PLoS Genet. 2017 Nov 1;13(11):e1007088. doi: 10.1371/journal.pgen.1007088. eCollection 2017 Nov.


Recombinant human IgG1 based Fc multimers, with limited FcR binding capacity, can effectively inhibit complement-mediated disease.

Sun H, Olsen HS, Mérigeon EY, So E, Burch E, Kinsey S, Papadimitriou JC, Drachenberg CB, Bentzen SM, Block DS, Strome SE, Zhang X.

J Autoimmun. 2017 Nov;84:97-108. doi: 10.1016/j.jaut.2017.08.004. Epub 2017 Aug 19.


Correction: A Conserved Nuclear Cyclophilin Is Required for Both RNA Polymerase II Elongation and Co-transcriptional Splicing in Caenorhabditis elegans.

Ahn JH, Rechtsteiner A, Strome S, Kelly WG.

PLoS Genet. 2017 May 31;13(5):e1006821. doi: 10.1371/journal.pgen.1006821. eCollection 2017 May.


What additional treatment is indicated for oral cavity cancer with isolated perineural invasion?

Hatten KM, Gupta N, Strome SE.

Laryngoscope. 2017 Sep;127(9):1965-1966. doi: 10.1002/lary.26577. Epub 2017 Mar 27. No abstract available.


Germ Granules Prevent Accumulation of Somatic Transcripts in the Adult Caenorhabditis elegans Germline.

Knutson AK, Egelhofer T, Rechtsteiner A, Strome S.

Genetics. 2017 May;206(1):163-178. doi: 10.1534/genetics.116.198549. Epub 2017 Mar 3.


Inheritance of protection from osmotic stress.

Kaneshiro KR, Strome S.

Nat Cell Biol. 2017 Mar 1;19(3):151-152. doi: 10.1038/ncb3483.


Modulating immunogenicity of factor IX by fusion to an immunoglobulin Fc domain: a study using a hemophilia B mouse model.

Levin D, Lagassé HA, Burch E, Strome S, Tan S, Jiang H, Sauna ZE, Golding B.

J Thromb Haemost. 2017 Apr;15(4):721-734. doi: 10.1111/jth.13649. Epub 2017 Mar 2.


Elements of Access.

Strome S, Johns T, Scicchitano MJ, Shelnutt K.

Int Q Community Health Educ. 2016 Jan 1:272684X16685252. doi: 10.1177/0272684X16685252. [Epub ahead of print]


Immunotherapy of head and neck cancer: Emerging clinical trials from a National Cancer Institute Head and Neck Cancer Steering Committee Planning Meeting.

Bauman JE, Cohen E, Ferris RL, Adelstein DJ, Brizel DM, Ridge JA, O'Sullivan B, Burtness BA, Butterfield LH, Carson WE, Disis ML, Fox BA, Gajewski TF, Gillison ML, Hodge JW, Le QT, Raben D, Strome SE, Lynn J, Malik S.

Cancer. 2017 Apr 1;123(7):1259-1271. doi: 10.1002/cncr.30449. Epub 2016 Dec 1.


A Conserved Nuclear Cyclophilin Is Required for Both RNA Polymerase II Elongation and Co-transcriptional Splicing in Caenorhabditis elegans.

Ahn JH, Rechsteiner A, Strome S, Kelly WG.

PLoS Genet. 2016 Aug 19;12(8):e1006227. doi: 10.1371/journal.pgen.1006227. eCollection 2016 Aug. Erratum in: PLoS Genet. 2017 May 31;13(5):e1006821.


The role of antagonists of the PD-1:PD-L1/PD-L2 axis in head and neck cancer treatment.

Pai SI, Zandberg DP, Strome SE.

Oral Oncol. 2016 Oct;61:152-8. doi: 10.1016/j.oraloncology.2016.08.001. Epub 2016 Aug 5. Review.


Structural basis for LIN54 recognition of CHR elements in cell cycle-regulated promoters.

Marceau AH, Felthousen JG, Goetsch PD, Iness AN, Lee HW, Tripathi SM, Strome S, Litovchick L, Rubin SM.

Nat Commun. 2016 Jul 28;7:12301. doi: 10.1038/ncomms12301.


Reevaluation of whether a soma-to-germ-line transformation extends lifespan in Caenorhabditis elegans.

Knutson AK, Rechtsteiner A, Strome S.

Proc Natl Acad Sci U S A. 2016 Mar 29;113(13):3591-6. doi: 10.1073/pnas.1523402113. Epub 2016 Mar 14.


Anti-CD20 Antibody with Multimerized Fc Domains: A Novel Strategy To Deplete B Cells and Augment Treatment of Autoimmune Disease.

Zhang X, Olsen HS, Chen S, So E, Zhou H, Burch E, Mérigeon EY, Block DS, Strome SE.

J Immunol. 2016 Feb 1;196(3):1165-76. doi: 10.4049/jimmunol.1501755. Epub 2015 Dec 22.


Caenorhabditis elegans polo-like kinase PLK-1 is required for merging parental genomes into a single nucleus.

Rahman MM, Munzig M, Kaneshiro K, Lee B, Strome S, Müller-Reichert T, Cohen-Fix O.

Mol Biol Cell. 2015 Dec 15;26(25):4718-35. doi: 10.1091/mbc.E15-04-0244. Epub 2015 Oct 21.


RFX transcription factors are essential for hearing in mice.

Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R.

Nat Commun. 2015 Oct 15;6:8549. doi: 10.1038/ncomms9549.


Impact of Detachment Methods on M2 Macrophage Phenotype and Function.

Chen S, So EC, Strome SE, Zhang X.

J Immunol Methods. 2015 Nov;426:56-61. doi: 10.1016/j.jim.2015.08.001. Epub 2015 Aug 5.


Specifying and protecting germ cell fate.

Strome S, Updike D.

Nat Rev Mol Cell Biol. 2015 Jul;16(7):406-16. doi: 10.1038/nrm4009. Review.


The DREAM complex promotes gene body H2A.Z for target repression.

Latorre I, Chesney MA, Garrigues JM, Stempor P, Appert A, Francesconi M, Strome S, Ahringer J.

Genes Dev. 2015 Mar 1;29(5):495-500. doi: 10.1101/gad.255810.114.

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