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Items: 1 to 20 of 205


A first-in-human phase I study to determine the maximum tolerated dose of the oral Src/ABL inhibitor AZD0424.

Woodcock VK, Clive S, Wilson RH, Coyle VM, Stratford MRL, Folkes LK, Eastell R, Barton C, Jones P, Kazmi-Stokes S, Turner H, Halford S, Harris AL, Middleton MR.

Br J Cancer. 2018 Mar 20;118(6):770-776. doi: 10.1038/bjc.2017.484. Epub 2018 Feb 13.


Radiosensitization In Vivo by Histone Deacetylase Inhibition with No Increase in Early Normal Tissue Radiation Toxicity.

Groselj B, Ruan JL, Scott H, Gorrill J, Nicholson J, Kelly J, Anbalagan S, Thompson J, Stratford MRL, Jevons SJ, Hammond EM, Scudamore CL, Kerr M, Kiltie AE.

Mol Cancer Ther. 2018 Feb;17(2):381-392. doi: 10.1158/1535-7163.MCT-17-0011. Epub 2017 Aug 24.


The anti-malarial atovaquone increases radiosensitivity by alleviating tumour hypoxia.

Ashton TM, Fokas E, Kunz-Schughart LA, Folkes LK, Anbalagan S, Huether M, Kelly CJ, Pirovano G, Buffa FM, Hammond EM, Stratford M, Muschel RJ, Higgins GS, McKenna WG.

Nat Commun. 2016 Jul 25;7:12308. doi: 10.1038/ncomms12308.


Metabolic activity in dormant conidia of Aspergillus niger and developmental changes during conidial outgrowth.

Novodvorska M, Stratford M, Blythe MJ, Wilson R, Beniston RG, Archer DB.

Fungal Genet Biol. 2016 Sep;94:23-31. doi: 10.1016/j.fgb.2016.07.002. Epub 2016 Jul 1.


The radiosensitizing effects of Nelfinavir on pancreatic cancer with and without pancreatic stellate cells.

Al-Assar O, Bittner MI, Lunardi S, Stratford MR, McKenna WG, Brunner TB.

Radiother Oncol. 2016 May;119(2):300-5. doi: 10.1016/j.radonc.2016.03.024. Epub 2016 May 28.


Investigation of the anomalous action of 5-hydroxyresorcinol on tyrosinase.

Land EJ, Ramsden CA, Riley PA, Stratford MR.

Pigment Cell Melanoma Res. 2016 Jul;29(4):474-6. doi: 10.1111/pcmr.12490. No abstract available.


Design, synthesis and evaluation of molecularly targeted hypoxia-activated prodrugs.

O'Connor LJ, Cazares-Körner C, Saha J, Evans CN, Stratford MR, Hammond EM, Conway SJ.

Nat Protoc. 2016 Apr;11(4):781-94. doi: 10.1038/nprot.2016.034. Epub 2016 Mar 24.


Prebiotic administration normalizes lipopolysaccharide (LPS)-induced anxiety and cortical 5-HT2A receptor and IL1-β levels in male mice.

Savignac HM, Couch Y, Stratford M, Bannerman DM, Tzortzis G, Anthony DC, Burnet PWJ.

Brain Behav Immun. 2016 Feb;52:120-131. doi: 10.1016/j.bbi.2015.10.007.


A Multicenter Randomized Trial of Ibandronate Compared With Single-Dose Radiotherapy for Localized Metastatic Bone Pain in Prostate Cancer.

Hoskin P, Sundar S, Reczko K, Forsyth S, Mithal N, Sizer B, Bloomfield D, Upadhyay S, Wilson P, Kirkwood A, Stratford M, Jitlal M, Hackshaw A.

J Natl Cancer Inst. 2015 Aug 4;107(10). pii: djv197. doi: 10.1093/jnci/djv197. Print 2015 Oct.


Oxidative calcium release from catechol.

Riley PA, Stratford MR.

Bioorg Med Chem Lett. 2015 Apr 1;25(7):1453-4. doi: 10.1016/j.bmcl.2015.02.036. Epub 2015 Feb 23.


Development of an enzymatic pretargeting strategy for dual-modality imaging.

Knight JC, Mosley M, Stratford MR, Uyeda HT, Benink HA, Cong M, Fan F, Faulkner S, Cornelissen B.

Chem Commun (Camb). 2015 Mar 7;51(19):4055-8. doi: 10.1039/c4cc10265g.


Dual-action combination therapy enhances angiogenesis while reducing tumor growth and spread.

Wong PP, Demircioglu F, Ghazaly E, Alrawashdeh W, Stratford MR, Scudamore CL, Cereser B, Crnogorac-Jurcevic T, McDonald S, Elia G, Hagemann T, Kocher HM, Hodivala-Dilke KM.

Cancer Cell. 2015 Jan 12;27(1):123-37. doi: 10.1016/j.ccell.2014.10.015.


A novel biosensor for quantitative monitoring of on-target activity of paclitaxel.

Townley HE, Zheng Y, Goldsmith J, Zheng YY, Stratford MR, Dobson PJ, Ahmed AA.

Nanoscale. 2015 Jan 21;7(3):1127-35. doi: 10.1039/c4nr01105h.


Deoxycytidine kinase expression underpins response to gemcitabine in bladder cancer.

Kerr M, Scott HE, Groselj B, Stratford MR, Karaszi K, Sharma NL, Kiltie AE.

Clin Cancer Res. 2014 Nov 1;20(21):5435-45. doi: 10.1158/1078-0432.CCR-14-0542. Epub 2014 Sep 15.


Cofactor Strap regulates oxidative phosphorylation and mitochondrial p53 activity through ATP synthase.

Maniam S, Coutts AS, Stratford MR, McGouran J, Kessler B, La Thangue NB.

Cell Death Differ. 2015 Jan;22(1):156-63. doi: 10.1038/cdd.2014.135. Epub 2014 Aug 29.


Germination of Aspergillus niger conidia is triggered by nitrogen compounds related to L-amino acids.

Hayer K, Stratford M, Archer DB.

Appl Environ Microbiol. 2014 Oct;80(19):6046-53. doi: 10.1128/AEM.01078-14. Epub 2014 Jul 25.


Rapid identification of the genus Dekkera/Brettanomyces, the Dekkera subgroup and all individual species.

Hulin M, Harrison E, Stratford M, Wheals AE.

Int J Food Microbiol. 2014 Sep 18;187:7-14. doi: 10.1016/j.ijfoodmicro.2014.06.028. Epub 2014 Jul 4.


Corrigendum to "Systemic inflammation alters central 5-HT function as determined by pharmacological MRI" [Neuroimage 75 (2013) 177-186].

Couch Y, Martin CJ, Howarth C, Raley J, Khrapitchev AA, Stratford M, Sharp T, Sibson NR, Anthony DC.

Neuroimage. 2014 Jul 1;94:413. doi: 10.1016/j.neuroimage.2014.03.021. Epub 2014 Mar 18. No abstract available.


Population heterogeneity and dynamics in starter culture and lag phase adaptation of the spoilage yeast Zygosaccharomyces bailii to weak acid preservatives.

Stratford M, Steels H, Nebe-von-Caron G, Avery SV, Novodvorska M, Archer DB.

Int J Food Microbiol. 2014 Jul 2;181:40-7. doi: 10.1016/j.ijfoodmicro.2014.04.017. Epub 2014 Apr 21.


Regulation of O2 consumption by the PI3K and mTOR pathways contributes to tumor hypoxia.

Kelly CJ, Hussien K, Fokas E, Kannan P, Shipley RJ, Ashton TM, Stratford M, Pearson N, Muschel RJ.

Radiother Oncol. 2014 Apr;111(1):72-80. doi: 10.1016/j.radonc.2014.02.007. Epub 2014 Mar 13.

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