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Items: 1 to 20 of 70

1.

Bacterial membrane vesicles transport their DNA cargo into host cells.

Bitto NJ, Chapman R, Pidot S, Costin A, Lo C, Choi J, D'Cruze T, Reynolds EC, Dashper SG, Turnbull L, Whitchurch CB, Stinear TP, Stacey KJ, Ferrero RL.

Sci Rep. 2017 Aug 1;7(1):7072. doi: 10.1038/s41598-017-07288-4.

2.

Structural basis of TIR-domain-assembly formation in MAL- and MyD88-dependent TLR4 signaling.

Ve T, Vajjhala PR, Hedger A, Croll T, DiMaio F, Horsefield S, Yu X, Lavrencic P, Hassan Z, Morgan GP, Mansell A, Mobli M, O'Carroll A, Chauvin B, Gambin Y, Sierecki E, Landsberg MJ, Stacey KJ, Egelman EH, Kobe B.

Nat Struct Mol Biol. 2017 Sep;24(9):743-751. doi: 10.1038/nsmb.3444. Epub 2017 Jul 31.

PMID:
28759049
3.

The molecular mechanisms of signaling by cooperative assembly formation in innate immunity pathways.

Vajjhala PR, Ve T, Bentham A, Stacey KJ, Kobe B.

Mol Immunol. 2017 Jun;86:23-37. doi: 10.1016/j.molimm.2017.02.012. Epub 2017 Feb 27. Review.

PMID:
28249680
4.

Dengue virus NS1 protein activates immune cells via TLR4 but not TLR2 or TLR6.

Modhiran N, Watterson D, Blumenthal A, Baxter AG, Young PR, Stacey KJ.

Immunol Cell Biol. 2017 May;95(5):491-495. doi: 10.1038/icb.2017.5. Epub 2017 Feb 21.

PMID:
28220810
5.

Cryo-EM Structure of Caspase-8 Tandem DED Filament Reveals Assembly and Regulation Mechanisms of the Death-Inducing Signaling Complex.

Fu TM, Li Y, Lu A, Li Z, Vajjhala PR, Cruz AC, Srivastava DB, DiMaio F, Penczek PA, Siegel RM, Stacey KJ, Egelman EH, Wu H.

Mol Cell. 2016 Oct 20;64(2):236-250. doi: 10.1016/j.molcel.2016.09.009. Epub 2016 Oct 13.

PMID:
27746017
6.

Programmed Death-1 Ligand 2-Mediated Regulation of the PD-L1 to PD-1 Axis Is Essential for Establishing CD4(+) T Cell Immunity.

Karunarathne DS, Horne-Debets JM, Huang JX, Faleiro R, Leow CY, Amante F, Watkins TS, Miles JJ, Dwyer PJ, Stacey KJ, Yarski M, Poh CM, Lee JS, Cooper MA, Rénia L, Richard D, McCarthy JS, Sharpe AH, Wykes MN.

Immunity. 2016 Aug 16;45(2):333-45. doi: 10.1016/j.immuni.2016.07.017.

7.

Assessment of Inflammasome Formation by Flow Cytometry.

Sester DP, Zamoshnikova A, Thygesen SJ, Vajjhala PR, Cridland SO, Schroder K, Stacey KJ.

Curr Protoc Immunol. 2016 Aug 1;114:14.40.1-14.40.29. doi: 10.1002/cpim.13.

PMID:
27479658
8.

Correction: Response to Comment on "Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice".

Sester DP, Stacey KJ.

J Immunol. 2016 Jul 15;197(2):676. doi: 10.4049/jimmunol.1600898. No abstract available.

9.

Salmonella employs multiple mechanisms to subvert the TLR-inducible zinc-mediated antimicrobial response of human macrophages.

Kapetanovic R, Bokil NJ, Achard ME, Ong CL, Peters KM, Stocks CJ, Phan MD, Monteleone M, Schroder K, Irvine KM, Saunders BM, Walker MJ, Stacey KJ, McEwan AG, Schembri MA, Sweet MJ.

FASEB J. 2016 May;30(5):1901-12. doi: 10.1096/fj.201500061. Epub 2016 Feb 2.

10.

Correcting the NLRP3 inflammasome deficiency in macrophages from autoimmune NZB mice with exon skipping antisense oligonucleotides.

Thygesen SJ, Sester DP, Cridland SO, Wilton SD, Stacey KJ.

Immunol Cell Biol. 2016 May;94(5):520-4. doi: 10.1038/icb.2016.3. Epub 2016 Feb 2.

PMID:
26833024
11.

Induction of interferon and cell death in response to cytosolic DNA in chicken macrophages.

Vitak N, Hume DA, Chappell KJ, Sester DP, Stacey KJ.

Dev Comp Immunol. 2016 Jun;59:145-52. doi: 10.1016/j.dci.2016.01.023. Epub 2016 Jan 29.

PMID:
26828392
12.

Methods for Delivering DNA to Intracellular Receptors.

Stacey KJ, Idris A, Sagulenko V, Vitak N, Sester DP.

Methods Mol Biol. 2016;1390:93-106. doi: 10.1007/978-1-4939-3335-8_6.

PMID:
26803624
14.

Response to Comment on "Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice".

Sester DP, Stacey KJ.

J Immunol. 2015 Nov 15;195(10):4552-3. doi: 10.4049/jimmunol.1501930. No abstract available. Erratum in: J Immunol. 2016 Jul 15;197(2):676.

15.

The Inflammasome Adaptor ASC Induces Procaspase-8 Death Effector Domain Filaments.

Vajjhala PR, Lu A, Brown DL, Pang SW, Sagulenko V, Sester DP, Cridland SO, Hill JM, Schroder K, Stow JL, Wu H, Stacey KJ.

J Biol Chem. 2015 Dec 4;290(49):29217-30. doi: 10.1074/jbc.M115.687731. Epub 2015 Oct 14.

16.

Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity.

Modhiran N, Watterson D, Muller DA, Panetta AK, Sester DP, Liu L, Hume DA, Stacey KJ, Young PR.

Sci Transl Med. 2015 Sep 9;7(304):304ra142. doi: 10.1126/scitranslmed.aaa3863.

PMID:
26355031
17.

Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice.

Sester DP, Sagulenko V, Thygesen SJ, Cridland JA, Loi YS, Cridland SO, Masters SL, Genske U, Hornung V, Andoniou CE, Sweet MJ, Degli-Esposti MA, Schroder K, Stacey KJ.

J Immunol. 2015 Aug 1;195(3):1233-41. doi: 10.4049/jimmunol.1402859. Epub 2015 Jun 26.

18.

Strain- and host species-specific inflammasome activation, IL-1β release, and cell death in macrophages infected with uropathogenic Escherichia coli.

Schaale K, Peters KM, Murthy AM, Fritzsche AK, Phan MD, Totsika M, Robertson AA, Nichols KB, Cooper MA, Stacey KJ, Ulett GC, Schroder K, Schembri MA, Sweet MJ.

Mucosal Immunol. 2016 Jan;9(1):124-36. doi: 10.1038/mi.2015.44. Epub 2015 May 20.

PMID:
25993444
19.

A novel pathway of cell death in response to cytosolic DNA in Drosophila cells.

Vitak N, Johnson KN, Sester DP, Stacey KJ.

J Innate Immun. 2015;7(2):212-22. doi: 10.1159/000368276. Epub 2014 Nov 29.

20.

A novel flow cytometric method to assess inflammasome formation.

Sester DP, Thygesen SJ, Sagulenko V, Vajjhala PR, Cridland JA, Vitak N, Chen KW, Osborne GW, Schroder K, Stacey KJ.

J Immunol. 2015 Jan 1;194(1):455-62. doi: 10.4049/jimmunol.1401110. Epub 2014 Nov 17.

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