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Items: 1 to 20 of 526


DNA polymerase gamma (Polγ) deficiency triggers a selective mTORC2 prosurvival autophagy response via mitochondria-mediated ROS signaling.

Dhar SK, Bakthavatchalu V, Dhar B, Chen J, Tadahide I, Zhu H, Gao T, St Clair DK.

Oncogene. 2018 Jul 23. doi: 10.1038/s41388-018-0404-z. [Epub ahead of print]


Stem Cells to Inform the Neurobiology of Mental Illness.

Johnstone M, Hillary RF, St Clair D.

Curr Top Behav Neurosci. 2018 Jul 21. doi: 10.1007/7854_2018_57. [Epub ahead of print]


Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes.

Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium. Electronic address:; Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium.

Cell. 2018 Jun 14;173(7):1705-1715.e16. doi: 10.1016/j.cell.2018.05.046.


Estimation of Genetic Correlation via Linkage Disequilibrium Score Regression and Genomic Restricted Maximum Likelihood.

Ni G, Moser G; Schizophrenia Working Group of the Psychiatric Genomics Consortium, Wray NR, Lee SH.

Am J Hum Genet. 2018 Jun 7;102(6):1185-1194. doi: 10.1016/j.ajhg.2018.03.021. Epub 2018 May 10.


Extracellular redox state shift: A novel approach to target prostate cancer invasion.

Zhong W, Weiss HL, Jayswal RD, Hensley PJ, Downes LM, St Clair DK, Chaiswing L.

Free Radic Biol Med. 2018 Mar;117:99-109. doi: 10.1016/j.freeradbiomed.2018.01.023. Epub 2018 Feb 2.


Study of Novel Autoantibodies in Schizophrenia.

Whelan R, St Clair D, Mustard CJ, Hallford P, Wei J.

Schizophr Bull. 2018 Jan 24. doi: 10.1093/schbul/sbx175. [Epub ahead of print]


Using mouse transgenic and human stem cell technologies to model genetic mutations associated with schizophrenia and autism.

St Clair D, Johnstone M.

Philos Trans R Soc Lond B Biol Sci. 2018 Mar 19;373(1742). pii: 20170037. doi: 10.1098/rstb.2017.0037. Review.


Redox Paradox: A Novel Approach to Therapeutics-Resistant Cancer.

Chaiswing L, St Clair WH, St Clair DK.

Antioxid Redox Signal. 2018 Feb 21. doi: 10.1089/ars.2017.7485. [Epub ahead of print]


Oxidative stress-induced JNK/AP-1 signaling is a major pathway involved in selective apoptosis of myelodysplastic syndrome cells by Withaferin-A.

Oben KZ, Alhakeem SS, McKenna MK, Brandon JA, Mani R, Noothi SK, Jinpeng L, Akunuru S, Dhar SK, Singh IP, Liang Y, Wang C, Abdel-Latif A, Stills HF Jr, St Clair DK, Geiger H, Muthusamy N, Tohyama K, Gupta RC, Bondada S.

Oncotarget. 2017 Aug 24;8(44):77436-77452. doi: 10.18632/oncotarget.20497. eCollection 2017 Sep 29.


Hematopoietic Stem Cells: Normal Versus Malignant.

Carroll D, St Clair DK.

Antioxid Redox Signal. 2017 Dec 20. doi: 10.1089/ars.2017.7326. [Epub ahead of print]


Extracellular Vesicles Released by Cardiomyocytes in a Doxorubicin-Induced Cardiac Injury Mouse Model Contain Protein Biomarkers of Early Cardiac Injury.

Yarana C, Carroll D, Chen J, Chaiswing L, Zhao Y, Noel T, Alstott M, Bae Y, Dressler EV, Moscow JA, Butterfield DA, Zhu H, St Clair DK.

Clin Cancer Res. 2018 Apr 1;24(7):1644-1653. doi: 10.1158/1078-0432.CCR-17-2046. Epub 2017 Oct 25.


Chemotherapy-Induced Tissue Injury: An Insight into the Role of Extracellular Vesicles-Mediated Oxidative Stress Responses.

Yarana C, St Clair DK.

Antioxidants (Basel). 2017 Sep 28;6(4). pii: E75. doi: 10.3390/antiox6040075. Review.


Clinical and experimental studies of a novel P525R FUS mutation in amyotrophic lateral sclerosis.

Kuang L, Kamelgarn M, Arenas A, Gal J, Taylor D, Gong W, Brown M, St Clair D, Kasarskis EJ, Zhu H.

Neurol Genet. 2017 Jul 20;3(4):e172. doi: 10.1212/NXG.0000000000000172. eCollection 2017 Aug.


Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity.

Hendricks AE, Bochukova EG, Marenne G, Keogh JM, Atanassova N, Bounds R, Wheeler E, Mistry V, Henning E, Körner A, Muddyman D, McCarthy S, Hinney A, Hebebrand J, Scott RA, Langenberg C, Wareham NJ, Surendran P, Howson JM, Butterworth AS, Danesh J, Nordestgaard BG, Nielsen SF, Afzal S, Papadia S, Ashford S, Garg S, Millhauser GL, Palomino RI, Kwasniewska A, Tachmazidou I, O'Rahilly S, Zeggini E, Barroso I, Farooqi IS; Understanding Society Scientific Group; EPIC-CVD Consortium; UK10K Consortium.

Sci Rep. 2017 Jun 29;7(1):4394. doi: 10.1038/s41598-017-03054-8.


Differential antibody responses to gliadin-derived indigestible peptides in patients with schizophrenia.

McLean RT, Wilson P, St Clair D, Mustard CJ, Wei J.

Transl Psychiatry. 2017 May 9;7(5):e1121. doi: 10.1038/tp.2017.89.


Latexin Inactivation Enhances Survival and Long-Term Engraftment of Hematopoietic Stem Cells and Expands the Entire Hematopoietic System in Mice.

Liu Y, Zhang C, Li Z, Wang C, Jia J, Gao T, Hildebrandt G, Zhou D, Bondada S, Ji P, St Clair D, Liu J, Zhan C, Geiger H, Wang S, Liang Y.

Stem Cell Reports. 2017 Apr 11;8(4):991-1004. doi: 10.1016/j.stemcr.2017.02.009. Epub 2017 Mar 16.


Genetic correlation between amyotrophic lateral sclerosis and schizophrenia.

McLaughlin RL, Schijven D, van Rheenen W, van Eijk KR, O'Brien M, Kahn RS, Ophoff RA, Goris A, Bradley DG, Al-Chalabi A, van den Berg LH, Luykx JJ, Hardiman O, Veldink JH; Project MinE GWAS Consortium; Schizophrenia Working Group of the Psychiatric Genomics Consortium.

Nat Commun. 2017 Mar 21;8:14774. doi: 10.1038/ncomms14774.


Manganese superoxide dismutase deficiency triggers mitochondrial uncoupling and the Warburg effect.

Xu Y, Miriyala S, Fang F, Bakthavatchalu V, Noel T, Schnell DM, Wang C, St Clair WH, St Clair DK.

Oncogene. 2017 Jul 13;36(28):4087. doi: 10.1038/onc.2016.513. Epub 2017 Mar 13.


Differential Transcriptional Regulation in Roots of Tomato Near-Isogenic Lines in Response to Rapid-Onset Water Stress.

Arms EM, Yan Z, St Clair DA.

Front Plant Sci. 2017 Feb 21;8:166. doi: 10.3389/fpls.2017.00166. eCollection 2017.


A novel redox regulator, MnTnBuOE-2-PyP5+, enhances normal hematopoietic stem/progenitor cell function.

Zhao Y, Carroll DW, You Y, Chaiswing L, Wen R, Batinic-Haberle I, Bondada S, Liang Y, St Clair DK.

Redox Biol. 2017 Aug;12:129-138. doi: 10.1016/j.redox.2017.02.005. Epub 2017 Feb 10.

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