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Items: 10


Inhalation of the reactive aldehyde acrolein promotes antigen sensitization to ovalbumin and enhances neutrophilic inflammation.

O'Brien E, Spiess PC, Habibovic A, Hristova M, Bauer RA, Randall MJ, Poynter ME, van der Vliet A.

J Immunotoxicol. 2016;13(2):191-7. doi: 10.3109/1547691X.2015.1033571. Epub 2015 Apr 15.


Acrolein exposure suppresses antigen-induced pulmonary inflammation.

Spiess PC, Kasahara D, Habibovic A, Hristova M, Randall MJ, Poynter ME, van der Vliet A.

Respir Res. 2013 Oct 16;14:107. doi: 10.1186/1465-9921-14-107.


Microspheres targeted with a mesothelin antibody and loaded with doxorubicin reduce tumor volume of human mesotheliomas in xenografts.

Macura SL, Steinbacher JL, Macpherson MB, Lathrop MJ, Sayan M, Hillegass JM, Beuschel SL, Perkins TN, Spiess PC, van der Vliet A, Butnor KJ, Shukla A, Wadsworth M, Landry CC, Mossman BT.

BMC Cancer. 2013 Sep 11;13:400. doi: 10.1186/1471-2407-13-400.


Acrolein-induced activation of mitogen-activated protein kinase signaling is mediated by alkylation of thioredoxin reductase and thioredoxin 1.

Randall MJ, Spiess PC, Hristova M, Hondal RJ, van der Vliet A.

Redox Biol. 2013 Feb 22;1:265-75. doi: 10.1016/j.redox.2013.02.001. eCollection 2013.


Dual oxidase-1 is required for airway epithelial cell migration and bronchiolar reepithelialization after injury.

Gorissen SH, Hristova M, Habibovic A, Sipsey LM, Spiess PC, Janssen-Heininger YM, van der Vliet A.

Am J Respir Cell Mol Biol. 2013 Mar;48(3):337-45. doi: 10.1165/rcmb.2012-0393OC. Epub 2012 Dec 13.


The tobacco smoke component, acrolein, suppresses innate macrophage responses by direct alkylation of c-Jun N-terminal kinase.

Hristova M, Spiess PC, Kasahara DI, Randall MJ, Deng B, van der Vliet A.

Am J Respir Cell Mol Biol. 2012 Jan;46(1):23-33. doi: 10.1165/rcmb.2011-0134OC.


Proteomic profiling of acrolein adducts in human lung epithelial cells.

Spiess PC, Deng B, Hondal RJ, Matthews DE, van der Vliet A.

J Proteomics. 2011 Oct 19;74(11):2380-94. doi: 10.1016/j.jprot.2011.05.039. Epub 2011 Jun 17.


Protein thiol oxidation in murine airway epithelial cells in response to naphthalene or diethyl maleate.

Spiess PC, Morin D, Williams CR, Buckpitt AR.

Am J Respir Cell Mol Biol. 2010 Sep;43(3):316-25. doi: 10.1165/rcmb.2009-0135OC. Epub 2009 Oct 20.


Measurement of protein sulfhydryls in response to cellular oxidative stress using gel electrophoresis and multiplexed fluorescent imaging analysis.

Spiess PC, Morin D, Jewell WT, Buckpitt AR.

Chem Res Toxicol. 2008 May;21(5):1074-85. doi: 10.1021/tx8000708. Epub 2008 Apr 17.


Distribution of brevetoxin (PbTx-3) in mouse plasma: association with high-density lipoproteins.

Woofter RT, Spiess PC, Ramsdell JS.

Environ Health Perspect. 2005 Nov;113(11):1491-6.

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