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Items: 17


[KCNQ1: a new regulator of the epithelio-mesenchymal transition in colorectal cancers].

Rapetti-Mauss R, Borgese F, Harvey BJ, Soriani O.

Med Sci (Paris). 2018 Jan;34(1):21-24. doi: 10.1051/medsci/20183401006. Epub 2018 Jan 31. French. No abstract available.


Red blood cell Gardos channel (KCNN4): the essential determinant of erythrocyte dehydration in hereditary xerocytosis.

Rapetti-Mauss R, Picard V, Guitton C, Ghazal K, Proulle V, Badens C, Soriani O, Garçon L, Guizouarn H.

Haematologica. 2017 Oct;102(10):e415-e418. doi: 10.3324/haematol.2017.171389. Epub 2017 Jun 15. No abstract available.


Bidirectional KCNQ1:β-catenin interaction drives colorectal cancer cell differentiation.

Rapetti-Mauss R, Bustos V, Thomas W, McBryan J, Harvey H, Lajczak N, Madden SF, Pellissier B, Borgese F, Soriani O, Harvey BJ.

Proc Natl Acad Sci U S A. 2017 Apr 18;114(16):4159-4164. doi: 10.1073/pnas.1702913114. Epub 2017 Apr 3.


Sigma 1 Receptor and Ion Channel Dynamics in Cancer.

Soriani O, Rapetti-Mauss R.

Adv Exp Med Biol. 2017;964:63-77. doi: 10.1007/978-3-319-50174-1_6. Review.


Senicapoc: a potent candidate for the treatment of a subset of hereditary xerocytosis caused by mutations in the Gardos channel.

Rapetti-Mauss R, Soriani O, Vinti H, Badens C, Guizouarn H.

Haematologica. 2016 Nov;101(11):e431-e435. Epub 2016 Jul 21. No abstract available.


SK3/TRPC1/Orai1 complex regulates SOCE-dependent colon cancer cell migration: a novel opportunity to modulate anti-EGFR mAb action by the alkyl-lipid Ohmline.

Guéguinou M, Harnois T, Crottes D, Uguen A, Deliot N, Gambade A, Chantôme A, Haelters JP, Jaffrès PA, Jourdan ML, Weber G, Soriani O, Bougnoux P, Mignen O, Bourmeyster N, Constantin B, Lecomte T, Vandier C, Potier-Cartereau M.

Oncotarget. 2016 Jun 14;7(24):36168-36184. doi: 10.18632/oncotarget.8786.


Immature human dendritic cells enhance their migration through KCa3.1 channel activation.

Crottès D, Félix R, Meley D, Chadet S, Herr F, Audiger C, Soriani O, Vandier C, Roger S, Angoulvant D, Velge-Roussel F.

Cell Calcium. 2016 Apr;59(4):198-207. doi: 10.1016/j.ceca.2016.02.008. Epub 2016 Mar 4.


SIGMAR1 Regulates Membrane Electrical Activity in Response to Extracellular Matrix Stimulation to Drive Cancer Cell Invasiveness.

Crottès D, Rapetti-Mauss R, Alcaraz-Perez F, Tichet M, Gariano G, Martial S, Guizouarn H, Pellissier B, Loubat A, Popa A, Paquet A, Presta M, Tartare-Deckert S, Cayuela ML, Martin P, Borgese F, Soriani O.

Cancer Res. 2016 Feb 1;76(3):607-18. doi: 10.1158/0008-5472.CAN-15-1465. Epub 2015 Dec 8.


A mutation in the Gardos channel is associated with hereditary xerocytosis.

Rapetti-Mauss R, Lacoste C, Picard V, Guitton C, Lombard E, Loosveld M, Nivaggioni V, Dasilva N, Salgado D, Desvignes JP, Béroud C, Viout P, Bernard M, Soriani O, Vinti H, Lacroze V, Feneant-Thibault M, Thuret I, Guizouarn H, Badens C.

Blood. 2015 Sep 10;126(11):1273-80. doi: 10.1182/blood-2015-04-642496. Epub 2015 Jul 6.


A direct interaction between the sigma-1 receptor and the hERG voltage-gated K+ channel revealed by atomic force microscopy and homogeneous time-resolved fluorescence (HTRF®).

Balasuriya D, D'Sa L, Talker R, Dupuis E, Maurin F, Martin P, Borgese F, Soriani O, Edwardson JM.

J Biol Chem. 2014 Nov 14;289(46):32353-63. doi: 10.1074/jbc.M114.603506. Epub 2014 Sep 29.


The sigma-1 receptor: a regulator of cancer cell electrical plasticity?

Crottès D, Guizouarn H, Martin P, Borgese F, Soriani O.

Front Physiol. 2013 Jul 16;4:175. doi: 10.3389/fphys.2013.00175. eCollection 2013.


The sigma-1 receptor binds to the Nav1.5 voltage-gated Na+ channel with 4-fold symmetry.

Balasuriya D, Stewart AP, Crottès D, Borgese F, Soriani O, Edwardson JM.

J Biol Chem. 2012 Oct 26;287(44):37021-9. doi: 10.1074/jbc.M112.382077. Epub 2012 Sep 5.


Sig1R protein regulates hERG channel expression through a post-translational mechanism in leukemic cells.

Crottès D, Martial S, Rapetti-Mauss R, Pisani DF, Loriol C, Pellissier B, Martin P, Chevet E, Borgese F, Soriani O.

J Biol Chem. 2011 Aug 12;286(32):27947-58. doi: 10.1074/jbc.M111.226738. Epub 2011 Jun 16.


Voltage-gated ion channels, new targets in anti-cancer research.

Le Guennec JY, Ouadid-Ahidouch H, Soriani O, Besson P, Ahidouch A, Vandier C.

Recent Pat Anticancer Drug Discov. 2007 Nov;2(3):189-202. Review.


SP600125 inhibits Kv channels through a JNK-independent pathway in cancer cells.

Martial S, Giorgelli JL, Renaudo A, Derijard B, Soriani O.

Biochem Biophys Res Commun. 2008 Feb 22;366(4):944-50. Epub 2007 Dec 17.


Cancer cell cycle modulated by a functional coupling between sigma-1 receptors and Cl- channels.

Renaudo A, L'Hoste S, Guizouarn H, Borgèse F, Soriani O.

J Biol Chem. 2007 Jan 26;282(4):2259-67. Epub 2006 Nov 22.


Inhibition of tumor cell proliferation by sigma ligands is associated with K+ Channel inhibition and p27kip1 accumulation.

Renaudo A, Watry V, Chassot AA, Ponzio G, Ehrenfeld J, Soriani O.

J Pharmacol Exp Ther. 2004 Dec;311(3):1105-14. Epub 2004 Jul 26.


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