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Items: 1 to 20 of 131

1.

Ewing sarcoma.

Grünewald TGP, Cidre-Aranaz F, Surdez D, Tomazou EM, de Álava E, Kovar H, Sorensen PH, Delattre O, Dirksen U.

Nat Rev Dis Primers. 2018 Jul 5;4(1):5. doi: 10.1038/s41572-018-0003-x. Review.

PMID:
29977059
2.

Activity of translation regulator eukaryotic elongation factor-2 kinase is increased in Parkinson disease brain and its inhibition reduces alpha synuclein toxicity.

Jan A, Jansonius B, Delaidelli A, Bhanshali F, An YA, Ferreira N, Smits LM, Negri GL, Schwamborn JC, Jensen PH, Mackenzie IR, Taubert S, Sorensen PH.

Acta Neuropathol Commun. 2018 Jul 2;6(1):54. doi: 10.1186/s40478-018-0554-9.

3.

Insulin-like growth factor 1 receptor stabilizes the ETV6-NTRK3 chimeric oncoprotein by blocking its KPC1/Rnf123-mediated proteasomal degradation.

Tognon CE, Rafn B, Cetinbas NM, Kamura T, Trigo G, Rotblat B, Okumura F, Matsumoto M, Chow C, Davare M, Pollak M, Mayor T, Sorensen PH.

J Biol Chem. 2018 Jun 14. pii: jbc.RA117.000321. doi: 10.1074/jbc.RA117.000321. [Epub ahead of print]

4.

A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases.

Garzia L, Kijima N, Morrissy AS, De Antonellis P, Guerreiro-Stucklin A, Holgado BL, Wu X, Wang X, Parsons M, Zayne K, Manno A, Kuzan-Fischer C, Nor C, Donovan LK, Liu J, Qin L, Garancher A, Liu KW, Mansouri S, Luu B, Thompson YY, Ramaswamy V, Peacock J, Farooq H, Skowron P, Shih DJH, Li A, Ensan S, Robbins CS, Cybulsky M, Mitra S, Ma Y, Moore R, Mungall A, Cho YJ, Weiss WA, Chan JA, Hawkins CE, Massimino M, Jabado N, Zapotocky M, Sumerauer D, Bouffet E, Dirks P, Tabori U, Sorensen PHB, Brastianos PK, Aldape K, Jones SJM, Marra MA, Woodgett JR, Wechsler-Reya RJ, Fults DW, Taylor MD.

Cell. 2018 May 31;173(6):1549. doi: 10.1016/j.cell.2018.05.033. Epub 2018 May 31. No abstract available.

PMID:
29856958
5.

The RNA-binding protein YBX1 regulates epidermal progenitors at a posttranscriptional level.

Kwon E, Todorova K, Wang J, Horos R, Lee KK, Neel VA, Negri GL, Sorensen PH, Lee SW, Hentze MW, Mandinova A.

Nat Commun. 2018 Apr 30;9(1):1734. doi: 10.1038/s41467-018-04092-0.

6.
7.

Extending the Compatibility of the SP3 Paramagnetic Bead Processing Approach for Proteomics.

Moggridge S, Sorensen PH, Morin GB, Hughes CS.

J Proteome Res. 2018 Apr 6;17(4):1730-1740. doi: 10.1021/acs.jproteome.7b00913. Epub 2018 Mar 27.

PMID:
29565595
8.

A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases.

Garzia L, Kijima N, Morrissy AS, De Antonellis P, Guerreiro-Stucklin A, Holgado BL, Wu X, Wang X, Parsons M, Zayne K, Manno A, Kuzan-Fischer C, Nor C, Donovan LK, Liu J, Qin L, Garancher A, Liu KW, Mansouri S, Luu B, Thompson YY, Ramaswamy V, Peacock J, Farooq H, Skowron P, Shih DJH, Li A, Ensan S, Robbins CS, Cybulsky M, Mitra S, Ma Y, Moore R, Mungall A, Cho YJ, Weiss WA, Chan JA, Hawkins CE, Massimino M, Jabado N, Zapotocky M, Sumerauer D, Bouffet E, Dirks P, Tabori U, Sorensen PHB, Brastianos PK, Aldape K, Jones SJM, Marra MA, Woodgett JR, Wechsler-Reya RJ, Fults DW, Taylor MD.

Cell. 2018 Feb 22;172(5):1050-1062.e14. doi: 10.1016/j.cell.2018.01.038. Erratum in: Cell. 2018 May 31;173(6):1549.

PMID:
29474906
9.

Novel identification of STAT1 as a crucial mediator of ETV6-NTRK3-induced tumorigenesis.

Park J, Kim J, Park B, Yang KM, Sun EJ, Tognon CE, Sorensen PH, Kim SJ.

Oncogene. 2018 Apr;37(17):2270-2284. doi: 10.1038/s41388-017-0102-2. Epub 2018 Feb 2.

PMID:
29391602
10.

Translational control of aberrant stress responses as a hallmark of cancer.

El-Naggar AM, Sorensen PH.

J Pathol. 2018 Apr;244(5):650-666. doi: 10.1002/path.5030. Epub 2018 Feb 20. Review.

PMID:
29293271
11.

TEM8/ANTXR1-Specific CAR T Cells as a Targeted Therapy for Triple-Negative Breast Cancer.

Byrd TT, Fousek K, Pignata A, Szot C, Samaha H, Seaman S, Dobrolecki L, Salsman VS, Oo HZ, Bielamowicz K, Landi D, Rainusso N, Hicks J, Powell S, Baker ML, Wels WS, Koch J, Sorensen PH, Deneen B, Ellis MJ, Lewis MT, Hegde M, Fletcher BS, St Croix B, Ahmed N.

Cancer Res. 2018 Jan 15;78(2):489-500. doi: 10.1158/0008-5472.CAN-16-1911. Epub 2017 Nov 28. Erratum in: Cancer Res. 2018 Jun 15;78(12):3403.

PMID:
29183891
12.

hace1 Influences zebrafish cardiac development via ROS-dependent mechanisms.

Razaghi B, Steele SL, Prykhozhij SV, Stoyek MR, Hill JA, Cooper MD, McDonald L, Lin W, Daugaard M, Crapoulet N, Chacko S, Lewis SM, Scott IC, Sorensen PHB, Berman JN.

Dev Dyn. 2018 Feb;247(2):289-303. doi: 10.1002/dvdy.24600. Epub 2017 Oct 27.

PMID:
29024245
13.

eEF2K protects MYCN-amplified cells from starvation.

Delaidelli A, Leprivier G, Sorensen PH.

Cell Cycle. 2017 Sep 17;16(18):1633-1634. doi: 10.1080/15384101.2017.1355180. Epub 2017 Aug 2. No abstract available.

PMID:
28767324
14.

Ewing sarcoma partial regression without GvHD by chondromodulin-I/HLA-A*02:01-specific allorestricted T cell receptor transgenic T cells.

Thiel U, Schober SJ, Einspieler I, Kirschner A, Thiede M, Schirmer D, Gall K, Blaeschke F, Schmidt O, Jabar S, Ranft A, Alba Rubío R, Dirksen U, Grunewald TGP, Sorensen PH, Richter GHS, von Lüttichau IT, Busch DH, Burdach SEG.

Oncoimmunology. 2017 Apr 12;6(5):e1312239. doi: 10.1080/2162402X.2017.1312239. eCollection 2017.

15.

Assessment of programmed death-ligand 1 expression and tumor-associated immune cells in pediatric cancer tissues.

Majzner RG, Simon JS, Grosso JF, Martinez D, Pawel BR, Santi M, Merchant MS, Geoerger B, Hezam I, Marty V, Vielh P, Daugaard M, Sorensen PH, Mackall CL, Maris JM.

Cancer. 2017 Oct 1;123(19):3807-3815. doi: 10.1002/cncr.30724. Epub 2017 Jun 13.

PMID:
28608950
16.

MYCN amplified neuroblastoma requires the mRNA translation regulator eEF2 kinase to adapt to nutrient deprivation.

Delaidelli A, Negri GL, Jan A, Jansonius B, El-Naggar A, Lim JKM, Khan D, Zarni Oo H, Carnie CJ, Remke M, Maris JM, Leprivier G, Sorensen PH.

Cell Death Differ. 2017 Sep;24(9):1564-1576. doi: 10.1038/cdd.2017.79. Epub 2017 Jun 2.

PMID:
28574509
17.

The endochondral bone protein CHM1 sustains an undifferentiated, invasive phenotype, promoting lung metastasis in Ewing sarcoma.

von Heyking K, Calzada-Wack J, Göllner S, Neff F, Schmidt O, Hensel T, Schirmer D, Fasan A, Esposito I, Müller-Tidow C, Sorensen PH, Burdach S, Richter GHS.

Mol Oncol. 2017 Sep;11(9):1288-1301. doi: 10.1002/1878-0261.12057. Epub 2017 Aug 21.

18.

Identification of cancer-associated missense mutations in hace1 that impair cell growth control and Rac1 ubiquitylation.

Andrio E, Lotte R, Hamaoui D, Cherfils J, Doye A, Daugaard M, Sorensen PH, Bost F, Ruimy R, Mettouchi A, Lemichez E.

Sci Rep. 2017 Mar 20;7:44779. doi: 10.1038/srep44779.

19.

eEF2K inhibition blocks Aβ42 neurotoxicity by promoting an NRF2 antioxidant response.

Jan A, Jansonius B, Delaidelli A, Somasekharan SP, Bhanshali F, Vandal M, Negri GL, Moerman D, MacKenzie I, Calon F, Hayden MR, Taubert S, Sorensen PH.

Acta Neuropathol. 2017 Jan;133(1):101-119. doi: 10.1007/s00401-016-1634-1. Epub 2016 Oct 17.

PMID:
27752775
20.

An Aqueous Extract of Marine Microalgae Exhibits Antimetastatic Activity through Preferential Killing of Suspended Cancer Cells and Anticolony Forming Activity.

Somasekharan SP, El-Naggar A, Sorensen PH, Wang Y, Cheng H.

Evid Based Complement Alternat Med. 2016;2016:9730654. doi: 10.1155/2016/9730654. Epub 2016 Aug 31.

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