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Items: 14


PDE1C deficiency antagonizes pathological cardiac remodeling and dysfunction.

Knight WE, Chen S, Zhang Y, Oikawa M, Wu M, Zhou Q, Miller CL, Cai Y, Mickelsen DM, Moravec C, Small EM, Abe J, Yan C.

Proc Natl Acad Sci U S A. 2016 Oct 20. pii: 201607728. [Epub ahead of print]


Complex Interdependence Regulates Heterotypic Transcription Factor Distribution and Coordinates Cardiogenesis.

Luna-Zurita L, Stirnimann CU, Glatt S, Kaynak BL, Thomas S, Baudin F, Samee MA, He D, Small EM, Mileikovsky M, Nagy A, Holloway AK, Pollard KS, Müller CW, Bruneau BG.

Cell. 2016 Feb 25;164(5):999-1014. doi: 10.1016/j.cell.2016.01.004. Epub 2016 Feb 11.


Transcriptional control of cardiac fibroblast plasticity.

Lighthouse JK, Small EM.

J Mol Cell Cardiol. 2016 Feb;91:52-60. doi: 10.1016/j.yjmcc.2015.12.016. Epub 2015 Dec 22. Review.


Myocardin-related transcription factors control the motility of epicardium-derived cells and the maturation of coronary vessels.

Trembley MA, Velasquez LS, de Mesy Bentley KL, Small EM.

Development. 2015 Jan 1;142(1):21-30. doi: 10.1242/dev.116418.


Activation of MRTF-A-dependent gene expression with a small molecule promotes myofibroblast differentiation and wound healing.

Velasquez LS, Sutherland LB, Liu Z, Grinnell F, Kamm KE, Schneider JW, Olson EN, Small EM.

Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):16850-5. doi: 10.1073/pnas.1316764110. Epub 2013 Sep 30.


MicroRNA133a: a new variable in vascular smooth muscle cell phenotypic switching.

Miano JM, Small EM.

Circ Res. 2011 Sep 30;109(8):825-7. doi: 10.1161/CIRCRESAHA.111.254656. No abstract available.


Pervasive roles of microRNAs in cardiovascular biology.

Small EM, Olson EN.

Nature. 2011 Jan 20;469(7330):336-42. doi: 10.1038/nature09783. Review.


MicroRNA-218 regulates vascular patterning by modulation of Slit-Robo signaling.

Small EM, Sutherland LB, Rajagopalan KN, Wang S, Olson EN.

Circ Res. 2010 Nov 26;107(11):1336-44. doi: 10.1161/CIRCRESAHA.110.227926. Epub 2010 Oct 14.


Myocardin-related transcription factor-a controls myofibroblast activation and fibrosis in response to myocardial infarction.

Small EM, Thatcher JE, Sutherland LB, Kinoshita H, Gerard RD, Richardson JA, Dimaio JM, Sadek H, Kuwahara K, Olson EN.

Circ Res. 2010 Jul 23;107(2):294-304. doi: 10.1161/CIRCRESAHA.110.223172. Epub 2010 Jun 17.


MicroRNAs add a new dimension to cardiovascular disease.

Small EM, Frost RJ, Olson EN.

Circulation. 2010 Mar 2;121(8):1022-32. doi: 10.1161/CIRCULATIONAHA.109.889048. Review. No abstract available.


Regulation of PI3-kinase/Akt signaling by muscle-enriched microRNA-486.

Small EM, O'Rourke JR, Moresi V, Sutherland LB, McAnally J, Gerard RD, Richardson JA, Olson EN.

Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4218-23. doi: 10.1073/pnas.1000300107. Epub 2010 Feb 8.


MicroRNAs miR-143 and miR-145 modulate cytoskeletal dynamics and responsiveness of smooth muscle cells to injury.

Xin M, Small EM, Sutherland LB, Qi X, McAnally J, Plato CF, Richardson JA, Bassel-Duby R, Olson EN.

Genes Dev. 2009 Sep 15;23(18):2166-78. doi: 10.1101/gad.1842409. Epub 2009 Aug 31.


The myocardin-related transcription factor, MASTR, cooperates with MyoD to activate skeletal muscle gene expression.

Meadows SM, Warkman AS, Salanga MC, Small EM, Krieg PA.

Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1545-50. doi: 10.1073/pnas.0703918105. Epub 2008 Jan 29.


Essential roles of the bHLH transcription factor Hrt2 in repression of atrial gene expression and maintenance of postnatal cardiac function.

Xin M, Small EM, van Rooij E, Qi X, Richardson JA, Srivastava D, Nakagawa O, Olson EN.

Proc Natl Acad Sci U S A. 2007 May 8;104(19):7975-80. Epub 2007 Apr 27.

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