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Items: 1 to 20 of 34


Disease-modifying effects of orally bioavailable NF-κB inhibitors in dystrophin-deficient muscle.

Hammers DW, Sleeper MM, Forbes SC, Coker CC, Jirousek MR, Zimmer M, Walter GA, Sweeney HL.

JCI Insight. 2016 Dec 22;1(21):e90341. doi: 10.1172/jci.insight.90341.


Tadalafil Treatment Delays the Onset of Cardiomyopathy in Dystrophin-Deficient Hearts.

Hammers DW, Sleeper MM, Forbes SC, Shima A, Walter GA, Sweeney HL.

J Am Heart Assoc. 2016 Aug 9;5(8). pii: e003911. doi: 10.1161/JAHA.116.003911.


The Evolving Mcart Multimodal Imaging Core: Establishing a Protocol for Computed Tomography and Echocardiography in the Rhesus Macaque to Perform Longitudinal Analysis of Radiation-Induced Organ Injury.

de Faria EB, Barrow KR, Ruehle BT, Parker JT, Swartz E, Taylor-Howell C, Kieta KM, Lees CJ, Sleeper MM, Dobbin T, Baron AD, Mohindra P, MacVittie TJ.

Health Phys. 2015 Nov;109(5):479-92. doi: 10.1097/HP.0000000000000344.


Effects of acepromazine or methadone on midazolam-induced behavioral reactions in dogs.

Simon BT, Scallan EM, Siracusa C, Henderson A, Sleeper MM, Larenza Menzies MP.

Can Vet J. 2014 Sep;55(9):875-85.


The effect of neonatal gene therapy with a gamma retroviral vector on cardiac valve disease in mucopolysaccharidosis VII dogs after a decade.

Bigg PW, Sleeper MM, O'Donnell PA, Liu Y, Wu S, Casal ML, Haskins ME, Ponder KP.

Mol Genet Metab. 2013 Nov;110(3):311-8. doi: 10.1016/j.ymgme.2013.06.015. Epub 2013 Jun 25.


Pathogenesis of mitral valve disease in mucopolysaccharidosis VII dogs.

Bigg PW, Baldo G, Sleeper MM, O'Donnell PA, Bai H, Rokkam VR, Liu Y, Wu S, Giugliani R, Casal ML, Haskins ME, Ponder KP.

Mol Genet Metab. 2013 Nov;110(3):319-28. doi: 10.1016/j.ymgme.2013.06.013. Epub 2013 Jun 25.


Long-term wheel running compromises diaphragm function but improves cardiac and plantarflexor function in the mdx mouse.

Selsby JT, Acosta P, Sleeper MM, Barton ER, Sweeney HL.

J Appl Physiol (1985). 2013 Sep 1;115(5):660-6. doi: 10.1152/japplphysiol.00252.2013. Epub 2013 Jul 3.


Neonatal gene therapy with a gamma retroviral vector in mucopolysaccharidosis VI cats.

Ponder KP, O'Malley TM, Wang P, O'Donnell PA, Traas AM, Knox VW, Aguirre GA, Ellinwood NM, Metcalf JA, Wang B, Parkinson-Lawrence EJ, Sleeper MM, Brooks DA, Hopwood JJ, Haskins ME.

Mol Ther. 2012 May;20(5):898-907. doi: 10.1038/mt.2012.9. Epub 2012 Mar 6.


Long-term restoration of cardiac dystrophin expression in golden retriever muscular dystrophy following rAAV6-mediated exon skipping.

Bish LT, Sleeper MM, Forbes SC, Wang B, Reynolds C, Singletary GE, Trafny D, Morine KJ, Sanmiguel J, Cecchini S, Virag T, Vulin A, Beley C, Bogan J, Wilson JM, Vandenborne K, Kornegay JN, Walter GA, Kotin RM, Garcia L, Sweeney HL.

Mol Ther. 2012 Mar;20(3):580-9. doi: 10.1038/mt.2011.264. Epub 2011 Dec 6.


Long-term systemic myostatin inhibition via liver-targeted gene transfer in golden retriever muscular dystrophy.

Bish LT, Sleeper MM, Forbes SC, Morine KJ, Reynolds C, Singletary GE, Trafny D, Pham J, Bogan J, Kornegay JN, Vandenborne K, Walter GA, Sweeney HL.

Hum Gene Ther. 2011 Dec;22(12):1499-509. doi: 10.1089/hum.2011.102. Epub 2011 Aug 30.


Chronic losartan administration reduces mortality and preserves cardiac but not skeletal muscle function in dystrophic mice.

Bish LT, Yarchoan M, Sleeper MM, Gazzara JA, Morine KJ, Acosta P, Barton ER, Sweeney HL.

PLoS One. 2011;6(6):e20856. doi: 10.1371/journal.pone.0020856. Epub 2011 Jun 22.


Effects of aging and blood contamination on the urinary protein-creatinine ratio in captive chimpanzees (Pan troglodytes).

Lammey ML, Ely JJ, Zavaskis T, Videan E, Sleeper MM.

J Am Assoc Lab Anim Sci. 2011 May;50(3):374-7.


Cardiac gene transfer of short hairpin RNA directed against phospholamban effectively knocks down gene expression but causes cellular toxicity in canines.

Bish LT, Sleeper MM, Reynolds C, Gazzara J, Withnall E, Singletary GE, Buchlis G, Hui D, High KA, Gao G, Wilson JM, Sweeney HL.

Hum Gene Ther. 2011 Aug;22(8):969-77. doi: 10.1089/hum.2011.035. Epub 2011 Jun 8.


Evaluation of adeno-associated viral vectors for liver-directed gene transfer in dogs.

Bell P, Gao G, Haskins ME, Wang L, Sleeper M, Wang H, Calcedo R, Vandenberghe LH, Chen SJ, Weisse C, Withnall E, Wilson JM.

Hum Gene Ther. 2011 Aug;22(8):985-97. doi: 10.1089/hum.2010.194. Epub 2011 Apr 11.


Long-term amelioration of feline Mucopolysaccharidosis VI after AAV-mediated liver gene transfer.

Cotugno G, Annunziata P, Tessitore A, O'Malley T, Capalbo A, Faella A, Bartolomeo R, O'Donnell P, Wang P, Russo F, Sleeper MM, Knox VW, Fernandez S, Levanduski L, Hopwood J, De Leonibus E, Haskins M, Auricchio A.

Mol Ther. 2011 Mar;19(3):461-9. doi: 10.1038/mt.2010.257. Epub 2010 Nov 30.


Activin IIB receptor blockade attenuates dystrophic pathology in a mouse model of Duchenne muscular dystrophy.

Morine KJ, Bish LT, Selsby JT, Gazzara JA, Pendrak K, Sleeper MM, Barton ER, Lee SJ, Sweeney HL.

Muscle Nerve. 2010 Nov;42(5):722-30. doi: 10.1002/mus.21743.


Overexpression of SERCA1a in the mdx diaphragm reduces susceptibility to contraction-induced damage.

Morine KJ, Sleeper MM, Barton ER, Sweeney HL.

Hum Gene Ther. 2010 Dec;21(12):1735-9. doi: 10.1089/hum.2010.077.

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