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  • Showing results for skovbjerg h. krasilnikoff pa. maltase-glucoamylase and residual isomaltase in sucrose intolerant patients. Your search for Skovberg H. Krasilnikoff PA. Maltase-glucoamylase and residual isomaltase in sucrose intolerant patients retrieved no results.
J Pediatr Gastroenterol Nutr. 1986 May-Jun;5(3):365-71.

Maltase-glucoamylase and residual isomaltase in sucrose intolerant patients.

Abstract

Small intestinal biopsies from nine patients with sucrase-isomaltase deficiency (sucrose-intolerance) were analyzed. All patients lacked sucrase activity and three patients had a residual isomaltase activity and a corresponding isomaltase precipitate following immunoelectrophoresis. By polyacrylamide gel electrophoresis in sodium dodecyl sulfate followed by immunoblotting the residual isomaltase appeared as a single polypeptide with molecular weight of approximately 145,000. Maltase-glucoamylase in the biopsies was specifically quantitated by crossed immunoelectrophoresis. One of the patients had an almost total deficiency of maltase-glucoamylase in the biopsy, three patients had a normal amount of maltase-glucoamylase, and five patients constituted an intermediary group. These results indicate that some of the sucrase-isomaltase deficient patients also have a more or less pronounced deficiency of maltase-glucoamylase. The patients constitute an even more heterogeneous group than earlier suggested and should be classified by the amount not only of sucrase and isomaltase but also of maltase-glucoamylase.

PMID:
3088247
[Indexed for MEDLINE]

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