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Items: 1 to 20 of 54

1.

Tailoring of Proteostasis Networks with Heat Shock Factors.

Joutsen J, Sistonen L.

Cold Spring Harb Perspect Biol. 2018 Nov 12. pii: a034066. doi: 10.1101/cshperspect.a034066. [Epub ahead of print]

PMID:
30420555
2.

Increased HSF1 expression predicts shorter disease-specific survival of prostate cancer patients following radical prostatectomy.

Björk JK, Ahonen I, Mirtti T, Erickson A, Rannikko A, Bützow A, Nordling S, Lundin J, Lundin M, Sistonen L, Nees M, Åkerfelt M.

Oncotarget. 2018 Jul 27;9(58):31200-31213. doi: 10.18632/oncotarget.25756. eCollection 2018 Jul 27.

3.

HSP90 inhibitors disrupt a transient HSP90-HSF1 interaction and identify a noncanonical model of HSP90-mediated HSF1 regulation.

Kijima T, Prince TL, Tigue ML, Yim KH, Schwartz H, Beebe K, Lee S, Budzynski MA, Williams H, Trepel JB, Sistonen L, Calderwood S, Neckers L.

Sci Rep. 2018 May 3;8(1):6976. doi: 10.1038/s41598-018-25404-w.

4.

Frizzled-8 integrates Wnt-11 and transforming growth factor-β signaling in prostate cancer.

Murillo-Garzón V, Gorroño-Etxebarria I, Åkerfelt M, Puustinen MC, Sistonen L, Nees M, Carton J, Waxman J, Kypta RM.

Nat Commun. 2018 May 1;9(1):1747. doi: 10.1038/s41467-018-04042-w.

5.

The VIII International Congress on Stress Proteins in Biology and Medicine: täynnä henkeä.

Bonorino C, Sistonen L, Eriksson J, Mezger V, Santoro G, Hightower LE.

Cell Stress Chaperones. 2018 Mar;23(2):171-177. doi: 10.1007/s12192-018-0878-1. Review.

6.

Sumoylation of Notch1 represses its target gene expression during cell stress.

Antila CJM, Rraklli V, Blomster HA, Dahlström KM, Salminen TA, Holmberg J, Sistonen L, Sahlgren C.

Cell Death Differ. 2018 Mar;25(3):600-615. doi: 10.1038/s41418-017-0002-6. Epub 2018 Jan 5.

7.

Transcriptional response to stress is pre-wired by promoter and enhancer architecture.

Vihervaara A, Mahat DB, Guertin MJ, Chu T, Danko CG, Lis JT, Sistonen L.

Nat Commun. 2017 Aug 15;8(1):255. doi: 10.1038/s41467-017-00151-0.

8.

Chaperone co-inducer BGP-15 inhibits histone deacetylases and enhances the heat shock response through increased chromatin accessibility.

Budzyński MA, Crul T, Himanen SV, Toth N, Otvos F, Sistonen L, Vigh L.

Cell Stress Chaperones. 2017 Sep;22(5):717-728. doi: 10.1007/s12192-017-0798-5. Epub 2017 May 4.

9.

Effects of intrinsic aerobic capacity, aging and voluntary running on skeletal muscle sirtuins and heat shock proteins.

Karvinen S, Silvennoinen M, Vainio P, Sistonen L, Koch LG, Britton SL, Kainulainen H.

Exp Gerontol. 2016 Jun 15;79:46-54. doi: 10.1016/j.exger.2016.03.015. Epub 2016 Mar 31.

PMID:
27038700
10.

Structures of HSF2 reveal mechanisms for differential regulation of human heat-shock factors.

Jaeger AM, Pemble CW 4th, Sistonen L, Thiele DJ.

Nat Struct Mol Biol. 2016 Feb;23(2):147-54. doi: 10.1038/nsmb.3150. Epub 2016 Jan 4.

11.

Global SUMOylation on active chromatin is an acute heat stress response restricting transcription.

Niskanen EA, Malinen M, Sutinen P, Toropainen S, Paakinaho V, Vihervaara A, Joutsen J, Kaikkonen MU, Sistonen L, Palvimo JJ.

Genome Biol. 2015 Jul 28;16:153. doi: 10.1186/s13059-015-0717-y.

12.

Uncoupling Stress-Inducible Phosphorylation of Heat Shock Factor 1 from Its Activation.

Budzyński MA, Puustinen MC, Joutsen J, Sistonen L.

Mol Cell Biol. 2015 Jul;35(14):2530-40. doi: 10.1128/MCB.00816-14. Epub 2015 May 11.

13.

Cellular stress response cross talk maintains protein and energy homeostasis.

Swan CL, Sistonen L.

EMBO J. 2015 Feb 3;34(3):267-9. doi: 10.15252/embj.201490757. Epub 2015 Jan 2. No abstract available.

14.

Expression of HSF2 decreases in mitosis to enable stress-inducible transcription and cell survival.

Elsing AN, Aspelin C, Björk JK, Bergman HA, Himanen SV, Kallio MJ, Roos-Mattjus P, Sistonen L.

J Cell Biol. 2014 Sep 15;206(6):735-49. doi: 10.1083/jcb.201402002. Epub 2014 Sep 8.

15.

Heat shock in the springtime.

Morano KA, Sistonen L, Mezger V.

Cell Stress Chaperones. 2014 Nov;19(6):753-61. doi: 10.1007/s12192-014-0539-y. Epub 2014 Sep 9.

16.

HSF1 at a glance.

Vihervaara A, Sistonen L.

J Cell Sci. 2014 Jan 15;127(Pt 2):261-6. doi: 10.1242/jcs.132605. Review.

17.

Transcriptional response to stress in the dynamic chromatin environment of cycling and mitotic cells.

Vihervaara A, Sergelius C, Vasara J, Blom MA, Elsing AN, Roos-Mattjus P, Sistonen L.

Proc Natl Acad Sci U S A. 2013 Sep 3;110(36):E3388-97. doi: 10.1073/pnas.1305275110. Epub 2013 Aug 19.

18.

Protein inhibitor of activated STAT3 (PIAS3) protein promotes SUMOylation and nuclear sequestration of the intracellular domain of ErbB4 protein.

Sundvall M, Korhonen A, Vaparanta K, Anckar J, Halkilahti K, Salah Z, Aqeilan RI, Palvimo JJ, Sistonen L, Elenius K.

J Biol Chem. 2012 Jun 29;287(27):23216-26. doi: 10.1074/jbc.M111.335927. Epub 2012 May 14.

19.

Regulation of HSF1 function in the heat stress response: implications in aging and disease.

Anckar J, Sistonen L.

Annu Rev Biochem. 2011;80:1089-115. doi: 10.1146/annurev-biochem-060809-095203. Review.

PMID:
21417720
20.

Regulation of the members of the mammalian heat shock factor family.

Björk JK, Sistonen L.

FEBS J. 2010 Oct;277(20):4126-39. Review.

PMID:
20945529

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