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Items: 1 to 20 of 137

1.

A nomogram to predict 5-fluorouracil toxicity: when pharmacogenomics meets the patient.

Botticelli A, Onesti CE, Strigari L, Occhipinti M, Di Pietro FR, Cerbelli B, Petremolo A, Anselmi E, Macrini S, Roberto M, Falcone R, Lionetto L, Borro M, Milano A, Gentile G, Simmaco M, Marchetti P, Mazzuca F.

Anticancer Drugs. 2017 Mar 14. doi: 10.1097/CAD.0000000000000492. [Epub ahead of print]

PMID:
28296649
2.

Clinical applications of Personalized Medicine: a new paradigm and challenge.

Di Sanzo M, Fineschi V, Borro M, La Russa R, Santurro A, Scopetti M, Simmaco M, Frati P.

Curr Pharm Biotechnol. 2017 Feb 23. doi: 10.2174/1389201018666170224105600. [Epub ahead of print]

PMID:
28240172
3.

LC-MS/MS simultaneous analysis of allopregnanolone, epiallopregnanolone, pregnanolone, dehydroepiandrosterone and dehydroepiandrosterone 3-sulfate in human plasma.

Lionetto L, De Andrés F, Capi M, Curto M, Sabato D, Simmaco M, Bossù P, Sacchinelli E, Orfei MD, Piras F, Banaj N, Spalletta G.

Bioanalysis. 2017 Mar;9(6):527-539. doi: 10.4155/bio-2016-0262.

PMID:
28207286
4.

Personalised Healthcare: the DiMA clinical model.

Borro M, Gentile G, Fineschi V, Földes-Papp Z, Frati P, Santurro A, Lionetto L, Simmaco M.

Curr Pharm Biotechnol. 2017 Feb 8. doi: 10.2174/1389201018666170208125131. [Epub ahead of print]

PMID:
28183244
5.

Personalized Medicine applied to Forensic Sciences: new advances and perspectives for a tailored forensic approach.

Santurro A, Vullo AM, Borro M, Gentile G, La Russa R, Simmaco M, Frati P, Fineschi V.

Curr Pharm Biotechnol. 2017 Feb 7. doi: 10.2174/1389201018666170207141525. [Epub ahead of print]

PMID:
28176637
6.

Integrated OMICS tools for personalised medicine.

Borro M, Gentile G, Lionetto L, Simmaco M.

J Headache Pain. 2015 Dec;16(Suppl 1):A9. doi: 10.1186/1129-2377-16-S1-A9. No abstract available.

7.

The metabolite beta-aminoisobutyric acid and physical inactivity among hemodialysis patients.

Molfino A, Amabile MI, Ammann T, Farcomeni A, Lionetto L, Simmaco M, Lai S, Laviano A, Rossi Fanelli F, Chiappini MG, Muscaritoli M.

Nutrition. 2017 Feb;34:101-107. doi: 10.1016/j.nut.2016.07.012.

PMID:
28063504
8.

Evaluation of 5-fluorouracil degradation rate and Pharmacogenetic profiling to predict toxicity following adjuvant Capecitabine.

Roberto M, Romiti A, Botticelli A, Mazzuca F, Lionetto L, Gentile G, Paris I, Falcone R, Bassanelli M, Di Pietro FR, Onesti CE, Anselmi E, Macrini S, Simmaco M, Marchetti P.

Eur J Clin Pharmacol. 2017 Feb;73(2):157-164. doi: 10.1007/s00228-016-2160-8.

PMID:
27864592
9.

5-Fluorouracil degradation rate could predict toxicity in stages II-III colorectal cancer patients undergoing adjuvant FOLFOX.

Onesti CE, Botticelli A, La Torre M, Borro M, Gentile G, Romiti A, Lionetto L, Petremolo A, Occhipinti M, Roberto M, Falcone R, Simmaco M, Marchetti P, Mazzuca F.

Anticancer Drugs. 2017 Mar;28(3):322-326. doi: 10.1097/CAD.0000000000000453.

PMID:
27845948
10.

Hedonic sensitivity to natural rewards is affected by prenatal stress in a sex-dependent manner.

Reynaert ML, Marrocco J, Mairesse J, Lionetto L, Simmaco M, Deruyter L, Allorge D, Moles A, Pittaluga A, Maccari S, Morley-Fletcher S, Van Camp G, Nicoletti F.

Addict Biol. 2016 Nov;21(6):1072-1085. doi: 10.1111/adb.12270.

PMID:
26011513
11.

Pre-treatment assay of 5-fluorouracil degradation rate (5-FUDR) to improve prediction of 5-fluorouracil toxicity in gastro-esophageal cancer.

Borro M, Botticelli A, Mazzuca F, Onesti EC, Gentile G, Romiti A, Cerbelli B, Mazzotti E, Marchetti L, Lionetto L, Simmaco M, Marchetti P.

Oncotarget. 2016 Oct 11. doi: 10.18632/oncotarget.12571. [Epub ahead of print]

12.

Degradation Rate of 5-Fluorouracil in Metastatic Colorectal Cancer: A New Predictive Outcome Biomarker?

Botticelli A, Borro M, Onesti CE, Strigari L, Gentile G, Cerbelli B, Romiti A, Occhipinti M, Sebastiani C, Lionetto L, Marchetti L, Simmaco M, Marchetti P, Mazzuca F.

PLoS One. 2016 Sep 22;11(9):e0163105. doi: 10.1371/journal.pone.0163105.

13.

The TYMS-TSER polymorphism is associated with toxicity of low-dose capecitabine in patients with advanced gastrointestinal cancer.

Romiti A, Roberto M, D'Antonio C, Onesti CE, Barucca V, Milano A, Gentile G, Lionetto L, Medda E, Mazzuca F, Botticelli A, Falcone R, Simmaco M, Marchetti P.

Anticancer Drugs. 2016 Nov;27(10):1044-9. doi: 10.1097/CAD.0000000000000429.

PMID:
27557140
14.

Altered intestinal permeability in patients with relapsing-remitting multiple sclerosis: A pilot study.

Buscarinu MC, Cerasoli B, Annibali V, Policano C, Lionetto L, Capi M, Mechelli R, Romano S, Fornasiero A, Mattei G, Piras E, Angelini DF, Battistini L, Simmaco M, Umeton R, Salvetti M, Ristori G.

Mult Scler. 2017 Mar;23(3):442-446. doi: 10.1177/1352458516652498.

PMID:
27270497
15.

H2020 and Beyond: Skip Discrepancy between Theory and Practice of Personalized Medicine. A Position Paper by the Italian Society of Personalized Medicine.

Borro M, Simmaco M, Aceti A, Barni S, De Luca A, Fineschi V, Frati P, Girardi P, Miozzo M, Nati G, Nicoletti F, Santini D, Marchetti P.

Curr Pharm Biotechnol. 2016;17(10):926-9.

PMID:
27194357
16.

Altered kynurenine pathway metabolites in serum of chronic migraine patients.

Curto M, Lionetto L, Negro A, Capi M, Fazio F, Giamberardino MA, Simmaco M, Nicoletti F, Martelletti P.

J Headache Pain. 2015;17:47. doi: 10.1186/s10194-016-0638-5.

17.

CYP19A1 Genetic Polymorphisms rs4646 and Osteoporosis in Patients Treated with Aromatase Inhibitor-Based Adjuvant Therapy.

Mazzuca F, Botticelli A, Mazzotti E, La Torre M, Borro M, Marchetti L, Maddalena C, Gentile G, Simmaco M, Marchetti P.

Eurasian J Med. 2016 Feb;48(1):10-4. doi: 10.5152/eurasianjmed.2015.008.

18.

Altered serum levels of kynurenine metabolites in patients affected by cluster headache.

Curto M, Lionetto L, Negro A, Capi M, Perugino F, Fazio F, Giamberardino MA, Simmaco M, Nicoletti F, Martelletti P.

J Headache Pain. 2015;17:27. doi: 10.1186/s10194-016-0620-2.

19.

Pre-treatment evaluation of 5-fluorouracil degradation rate: association of poor and ultra-rapid metabolism with severe toxicity in a colorectal cancer patients cohort.

Mazzuca F, Borro M, Botticelli A, Mazzotti E, Marchetti L, Gentile G, La Torre M, Lionetto L, Simmaco M, Marchetti P.

Oncotarget. 2016 Apr 12;7(15):20612-20. doi: 10.18632/oncotarget.7991.

20.

Xanthurenic Acid Activates mGlu2/3 Metabotropic Glutamate Receptors and is a Potential Trait Marker for Schizophrenia.

Fazio F, Lionetto L, Curto M, Iacovelli L, Cavallari M, Zappulla C, Ulivieri M, Napoletano F, Capi M, Corigliano V, Scaccianoce S, Caruso A, Miele J, De Fusco A, Di Menna L, Comparelli A, De Carolis A, Gradini R, Nisticò R, De Blasi A, Girardi P, Bruno V, Battaglia G, Nicoletti F, Simmaco M.

Sci Rep. 2015 Dec 8;5:17799. doi: 10.1038/srep17799.

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