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Items: 1 to 20 of 23


The transcription factor CHOP, an effector of the integrated stress response, is required for host sensitivity to the fungal intracellular pathogen Histoplasma capsulatum.

English BC, Van Prooyen N, Örd T, Örd T, Sil A.

PLoS Pathog. 2017 Sep 27;13(9):e1006589. doi: 10.1371/journal.ppat.1006589. eCollection 2017 Sep.


CD103+ Conventional Dendritic Cells Are Critical for TLR7/9-Dependent Host Defense against Histoplasma capsulatum, an Endemic Fungal Pathogen of Humans.

Van Prooyen N, Henderson CA, Hocking Murray D, Sil A.

PLoS Pathog. 2016 Jul 26;12(7):e1005749. doi: 10.1371/journal.ppat.1005749. eCollection 2016 Jul.


Macrophage cell death and transcriptional response are actively triggered by the fungal virulence factor Cbp1 during H. capsulatum infection.

Isaac DT, Berkes CA, English BC, Murray DH, Lee YN, Coady A, Sil A.

Mol Microbiol. 2015 Dec;98(5):910-929. doi: 10.1111/mmi.13168. Epub 2015 Sep 29.


Genome-Wide Reprogramming of Transcript Architecture by Temperature Specifies the Developmental States of the Human Pathogen Histoplasma.

Gilmore SA, Voorhies M, Gebhart D, Sil A.

PLoS Genet. 2015 Jul 15;11(7):e1005395. doi: 10.1371/journal.pgen.1005395. eCollection 2015 Jul.


MyD88-dependent signaling drives host survival and early cytokine production during Histoplasma capsulatum infection.

Coady A, Sil A.

Infect Immun. 2015 Apr;83(4):1265-75. doi: 10.1128/IAI.02619-14. Epub 2015 Jan 12.


Thermally Dimorphic Human Fungal Pathogens--Polyphyletic Pathogens with a Convergent Pathogenicity Trait.

Sil A, Andrianopoulos A.

Cold Spring Harb Perspect Med. 2014 Nov 10;5(8):a019794. doi: 10.1101/cshperspect.a019794. Review.


N-acetylglucosamine (GlcNAc) triggers a rapid, temperature-responsive morphogenetic program in thermally dimorphic fungi.

Gilmore SA, Naseem S, Konopka JB, Sil A.

PLoS Genet. 2013;9(9):e1003799. doi: 10.1371/journal.pgen.1003799. Epub 2013 Sep 19.


A temperature-responsive network links cell shape and virulence traits in a primary fungal pathogen.

Beyhan S, Gutierrez M, Voorhies M, Sil A.

PLoS Biol. 2013 Jul;11(7):e1001614. doi: 10.1371/journal.pbio.1001614. Epub 2013 Jul 23.


Comparative transcriptomics of infectious spores from the fungal pathogen Histoplasma capsulatum reveals a core set of transcripts that specify infectious and pathogenic states.

Inglis DO, Voorhies M, Hocking Murray DR, Sil A.

Eukaryot Cell. 2013 Jun;12(6):828-52. doi: 10.1128/EC.00069-13. Epub 2013 Apr 5.


The 3-hydroxy-methylglutaryl coenzyme A lyase HCL1 is required for macrophage colonization by human fungal pathogen Histoplasma capsulatum.

Isaac DT, Coady A, Van Prooyen N, Sil A.

Infect Immun. 2013 Feb;81(2):411-20. doi: 10.1128/IAI.00833-12. Epub 2012 Nov 26.


SRE1 regulates iron-dependent and -independent pathways in the fungal pathogen Histoplasma capsulatum.

Hwang LH, Seth E, Gilmore SA, Sil A.

Eukaryot Cell. 2012 Jan;11(1):16-25. doi: 10.1128/EC.05274-11. Epub 2011 Nov 23.


A conserved transcriptional regulator governs fungal morphology in widely diverged species.

Cain CW, Lohse MB, Homann OR, Sil A, Johnson AD.

Genetics. 2012 Feb;190(2):511-21. doi: 10.1534/genetics.111.134080. Epub 2011 Nov 17.


Experimental annotation of the human pathogen Histoplasma capsulatum transcribed regions using high-resolution tiling arrays.

Voorhies M, Foo CK, Sil A.

BMC Microbiol. 2011 Sep 29;11:216. doi: 10.1186/1471-2180-11-216.


Conidia but not yeast cells of the fungal pathogen Histoplasma capsulatum trigger a type I interferon innate immune response in murine macrophages.

Inglis DO, Berkes CA, Hocking Murray DR, Sil A.

Infect Immun. 2010 Sep;78(9):3871-82. doi: 10.1128/IAI.00204-10. Epub 2010 Jul 6.


Conserved factors Ryp2 and Ryp3 control cell morphology and infectious spore formation in the fungal pathogen Histoplasma capsulatum.

Webster RH, Sil A.

Proc Natl Acad Sci U S A. 2008 Sep 23;105(38):14573-8. doi: 10.1073/pnas.0806221105. Epub 2008 Sep 12.


Histoplasma requires SID1, a member of an iron-regulated siderophore gene cluster, for host colonization.

Hwang LH, Mayfield JA, Rine J, Sil A.

PLoS Pathog. 2008 Apr 11;4(4):e1000044. doi: 10.1371/journal.ppat.1000044.


Temperature-induced switch to the pathogenic yeast form of Histoplasma capsulatum requires Ryp1, a conserved transcriptional regulator.

Nguyen VQ, Sil A.

Proc Natl Acad Sci U S A. 2008 Mar 25;105(12):4880-5. doi: 10.1073/pnas.0710448105. Epub 2008 Mar 13.


Identification of Histoplasma capsulatum transcripts induced in response to reactive nitrogen species.

Nittler MP, Hocking-Murray D, Foo CK, Sil A.

Mol Biol Cell. 2005 Oct;16(10):4792-813. Epub 2005 Jul 19.


Actin-dependent localization of an RNA encoding a cell-fate determinant in yeast.

Takizawa PA, Sil A, Swedlow JR, Herskowitz I, Vale RD.

Nature. 1997 Sep 4;389(6646):90-3.


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