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Items: 1 to 20 of 50

1.

PRMT5-PTEN molecular pathway regulates senescence and self-renewal of primary glioblastoma neurosphere cells.

Banasavadi-Siddegowda YK, Russell L, Frair E, Karkhanis VA, Relation T, Yoo JY, Zhang J, Sif S, Imitola J, Baiocchi R, Kaur B.

Oncogene. 2017 Jan 12;36(2):263-274. doi: 10.1038/onc.2016.199.

2.

Towards understanding the genetics of Autism.

Shailesh H, Gupta I, Sif S, Ouhtit A.

Front Biosci (Elite Ed). 2016 Jun 1;8:412-26.

PMID:
27100348
3.

Promoter-enhancer looping at the PPARγ2 locus during adipogenic differentiation requires the Prmt5 methyltransferase.

LeBlanc SE, Wu Q, Lamba P, Sif S, Imbalzano AN.

Nucleic Acids Res. 2016 Jun 20;44(11):5133-47. doi: 10.1093/nar/gkw129.

4.

Transcriptional and post-transcriptional control of adipocyte differentiation by Jumonji domain-containing protein 6.

Hu YJ, Belaghzal H, Hsiao WY, Qi J, Bradner JE, Guertin DA, Sif S, Imbalzano AN.

Nucleic Acids Res. 2015 Sep 18;43(16):7790-804. doi: 10.1093/nar/gkv645.

5.

Opposing calcium-dependent signalling pathways control skeletal muscle differentiation by regulating a chromatin remodelling enzyme.

Nasipak BT, Padilla-Benavides T, Green KM, Leszyk JD, Mao W, Konda S, Sif S, Shaffer SA, Ohkawa Y, Imbalzano AN.

Nat Commun. 2015 Jun 17;6:7441. doi: 10.1038/ncomms8441.

6.

Selective inhibition of protein arginine methyltransferase 5 blocks initiation and maintenance of B-cell transformation.

Alinari L, Mahasenan KV, Yan F, Karkhanis V, Chung JH, Smith EM, Quinion C, Smith PL, Kim L, Patton JT, Lapalombella R, Yu B, Wu Y, Roy S, De Leo A, Pileri S, Agostinelli C, Ayers L, Bradner JE, Chen-Kiang S, Elemento O, Motiwala T, Majumder S, Byrd JC, Jacob S, Sif S, Li C, Baiocchi RA.

Blood. 2015 Apr 16;125(16):2530-43. doi: 10.1182/blood-2014-12-619783.

8.

Genetic validation of the protein arginine methyltransferase PRMT5 as a candidate therapeutic target in glioblastoma.

Yan F, Alinari L, Lustberg ME, Martin LK, Cordero-Nieves HM, Banasavadi-Siddegowda Y, Virk S, Barnholtz-Sloan J, Bell EH, Wojton J, Jacob NK, Chakravarti A, Nowicki MO, Wu X, Lapalombella R, Datta J, Yu B, Gordon K, Haseley A, Patton JT, Smith PL, Ryu J, Zhang X, Mo X, Marcucci G, Nuovo G, Kwon CH, Byrd JC, Chiocca EA, Li C, Sif S, Jacob S, Lawler S, Kaur B, Baiocchi RA.

Cancer Res. 2014 Mar 15;74(6):1752-65. doi: 10.1158/0008-5472.CAN-13-0884.

9.

Cellular localization of protein arginine methyltransferase-5 correlates with grade of lung tumors.

Shilo K, Wu X, Sharma S, Welliver M, Duan W, Villalona-Calero M, Fukuoka J, Sif S, Baiocchi R, Hitchcock CL, Zhao W, Otterson GA.

Diagn Pathol. 2013 Dec 10;8:201. doi: 10.1186/1746-1596-8-201.

10.

The multifunctional protein fused in sarcoma (FUS) is a coactivator of microphthalmia-associated transcription factor (MITF).

Bronisz A, Carey HA, Godlewski J, Sif S, Ostrowski MC, Sharma SM.

J Biol Chem. 2014 Jan 3;289(1):326-34. doi: 10.1074/jbc.M113.493874.

11.

Protein arginine methyltransferase 5 (PRMT5) inhibition induces lymphoma cell death through reactivation of the retinoblastoma tumor suppressor pathway and polycomb repressor complex 2 (PRC2) silencing.

Chung J, Karkhanis V, Tae S, Yan F, Smith P, Ayers LW, Agostinelli C, Pileri S, Denis GV, Baiocchi RA, Sif S.

J Biol Chem. 2013 Dec 6;288(49):35534-47. doi: 10.1074/jbc.M113.510669.

12.

PRMT5 is upregulated in malignant and metastatic melanoma and regulates expression of MITF and p27(Kip1.).

Nicholas C, Yang J, Peters SB, Bill MA, Baiocchi RA, Yan F, Sïf S, Tae S, Gaudio E, Wu X, Grever MR, Young GS, Lesinski GB.

PLoS One. 2013 Sep 30;8(9):e74710. doi: 10.1371/journal.pone.0074710.

13.

Prmt7 is dispensable in tissue culture models for adipogenic differentiation.

Hu YJ, Sif S, Imbalzano AN.

F1000Res. 2013 Dec 18;2:279. doi: 10.12688/f1000research.2-279.v1.

14.

Protein arginine methyltransferase 7 regulates cellular response to DNA damage by methylating promoter histones H2A and H4 of the polymerase δ catalytic subunit gene, POLD1.

Karkhanis V, Wang L, Tae S, Hu YJ, Imbalzano AN, Sif S.

J Biol Chem. 2012 Aug 24;287(35):29801-14. doi: 10.1074/jbc.M112.378281.

15.

Protein arginine methyltransferase 5 (Prmt5) promotes gene expression of peroxisome proliferator-activated receptor γ2 (PPARγ2) and its target genes during adipogenesis.

LeBlanc SE, Konda S, Wu Q, Hu YJ, Oslowski CM, Sif S, Imbalzano AN.

Mol Endocrinol. 2012 Apr;26(4):583-97. doi: 10.1210/me.2011-1162.

16.

Versatility of PRMT5-induced methylation in growth control and development.

Karkhanis V, Hu YJ, Baiocchi RA, Imbalzano AN, Sif S.

Trends Biochem Sci. 2011 Dec;36(12):633-41. doi: 10.1016/j.tibs.2011.09.001. Review.

17.

Bromodomain protein 7 interacts with PRMT5 and PRC2, and is involved in transcriptional repression of their target genes.

Tae S, Karkhanis V, Velasco K, Yaneva M, Erdjument-Bromage H, Tempst P, Sif S.

Nucleic Acids Res. 2011 Jul;39(13):5424-38. doi: 10.1093/nar/gkr170.

18.

The expression of myogenic microRNAs indirectly requires protein arginine methyltransferase (Prmt)5 but directly requires Prmt4.

Mallappa C, Hu YJ, Shamulailatpam P, Tae S, Sif S, Imbalzano AN.

Nucleic Acids Res. 2011 Mar;39(4):1243-55. doi: 10.1093/nar/gkq896.

19.

Methylation of histone H3 and H4 by PRMT5 regulates ribosomal RNA gene transcription.

Majumder S, Alinari L, Roy S, Miller T, Datta J, Sif S, Baiocchi R, Jacob ST.

J Cell Biochem. 2010 Feb 15;109(3):553-63. doi: 10.1002/jcb.22432.

20.

Defective co-activator recruitment in osteoclasts from microphthalmia-oak ridge mutant mice.

Sharma SM, Sif S, Ostrowski MC, Sankar U.

J Cell Physiol. 2009 Jul;220(1):230-7. doi: 10.1002/jcp.21755.

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