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Items: 1 to 20 of 21


Quantitative in vivo CT arthrography of the human osteoarthritic knee to estimate cartilage sulphated glycosaminoglycan content: correlation with ex-vivo reference standards.

van Tiel J, Siebelt M, Reijman M, Bos PK, Waarsing JH, Zuurmond AM, Nasserinejad K, van Osch GJ, Verhaar JA, Krestin GP, Weinans H, Oei EH.

Osteoarthritis Cartilage. 2016 Jun;24(6):1012-20. doi: 10.1016/j.joca.2016.01.137. Epub 2016 Feb 3.


Triamcinolone acetonide activates an anti-inflammatory and folate receptor-positive macrophage that prevents osteophytosis in vivo.

Siebelt M, Korthagen N, Wei W, Groen H, Bastiaansen-Jenniskens Y, Müller C, Waarsing JH, de Jong M, Weinans H.

Arthritis Res Ther. 2015 Dec 5;17:352. doi: 10.1186/s13075-015-0865-1.


The role of imaging in early hip OA.

Siebelt M, Agricola R, Weinans H, Kim YJ.

Osteoarthritis Cartilage. 2014 Oct;22(10):1470-80. doi: 10.1016/j.joca.2014.04.030. Review.


Inhibited osteoclastic bone resorption through alendronate treatment in rats reduces severe osteoarthritis progression.

Siebelt M, Waarsing JH, Groen HC, Müller C, Koelewijn SJ, de Blois E, Verhaar JA, de Jong M, Weinans H.

Bone. 2014 Sep;66:163-70. doi: 10.1016/j.bone.2014.06.009. Epub 2014 Jun 13.


Mesenchymal stem cells reduce pain but not degenerative changes in a mono-iodoacetate rat model of osteoarthritis.

van Buul GM, Siebelt M, Leijs MJ, Bos PK, Waarsing JH, Kops N, Weinans H, Verhaar JA, Bernsen MR, van Osch GJ.

J Orthop Res. 2014 Sep;32(9):1167-74. doi: 10.1002/jor.22650. Epub 2014 May 16.


FK506 protects against articular cartilage collagenous extra-cellular matrix degradation.

Siebelt M, van der Windt AE, Groen HC, Sandker M, Waarsing JH, Müller C, de Jong M, Jahr H, Weinans H.

Osteoarthritis Cartilage. 2014 Apr;22(4):591-600. doi: 10.1016/j.joca.2014.02.003. Epub 2014 Feb 19.


Increased physical activity severely induces osteoarthritic changes in knee joints with papain induced sulfate-glycosaminoglycan depleted cartilage.

Siebelt M, Groen HC, Koelewijn SJ, de Blois E, Sandker M, Waarsing JH, Müller C, van Osch GJ, de Jong M, Weinans H.

Arthritis Res Ther. 2014 Jan 29;16(1):R32. doi: 10.1186/ar4461.


No effect of hole geometry in microfracture for talar osteochondral defects.

Kok AC, Tuijthof GJ, den Dunnen S, van Tiel J, Siebelt M, Everts V, van Dijk CN, Kerkhoffs GM.

Clin Orthop Relat Res. 2013 Nov;471(11):3653-62. doi: 10.1007/s11999-013-3189-y. Epub 2013 Jul 27.


In situ forming acyl-capped PCLA-PEG-PCLA triblock copolymer based hydrogels.

Sandker MJ, Petit A, Redout EM, Siebelt M, Müller B, Bruin P, Meyboom R, Vermonden T, Hennink WE, Weinans H.

Biomaterials. 2013 Oct;34(32):8002-11. doi: 10.1016/j.biomaterials.2013.07.046. Epub 2013 Jul 23.


Properties of commonly used calcium phosphate cements in trauma and orthopaedic surgery.

Van der Stok J, Weinans H, Kops N, Siebelt M, Patka P, Van Lieshout EM.

Injury. 2013 Oct;44(10):1368-74. doi: 10.1016/j.injury.2013.06.004. Epub 2013 Jul 19. No abstract available.


Assessment of articular cartilage and subchondral bone using EPIC-microCT in Labrador retrievers with incipient medial coronoid disease.

Lau SF, Wolschrijn CF, Siebelt M, Vernooij JC, Voorhout G, Hazewinkel HA.

Vet J. 2013 Oct;198(1):116-21. doi: 10.1016/j.tvjl.2013.05.038. Epub 2013 Jul 8.


Enhanced bone regeneration of cortical segmental bone defects using porous titanium scaffolds incorporated with colloidal gelatin gels for time- and dose-controlled delivery of dual growth factors.

van der Stok J, Wang H, Amin Yavari S, Siebelt M, Sandker M, Waarsing JH, Verhaar JA, Jahr H, Zadpoor AA, Leeuwenburgh SC, Weinans H.

Tissue Eng Part A. 2013 Dec;19(23-24):2605-14. doi: 10.1089/ten.TEA.2013.0181. Epub 2013 Aug 17.


Delayed endochondral ossification in early medial coronoid disease (MCD): a morphological and immunohistochemical evaluation in growing Labrador retrievers.

Lau SF, Hazewinkel HA, Grinwis GC, Wolschrijn CF, Siebelt M, Vernooij JC, Voorhout G, Tryfonidou MA.

Vet J. 2013 Sep;197(3):731-8. doi: 10.1016/j.tvjl.2013.04.021. Epub 2013 Jun 6.


The early development of medial coronoid disease in growing Labrador retrievers: radiographic, computed tomographic, necropsy and micro-computed tomographic findings.

Lau SF, Wolschrijn CF, Hazewinkel HA, Siebelt M, Voorhout G.

Vet J. 2013 Sep;197(3):724-30. doi: 10.1016/j.tvjl.2013.04.002. Epub 2013 May 20.


Hsp90 inhibition protects against biomechanically induced osteoarthritis in rats.

Siebelt M, Jahr H, Groen HC, Sandker M, Waarsing JH, Kops N, Müller C, van Eden W, de Jong M, Weinans H.

Arthritis Rheum. 2013 Aug;65(8):2102-12. doi: 10.1002/art.38000.


CT arthrography of the human knee to measure cartilage quality with low radiation dose.

van Tiel J, Siebelt M, Waarsing JH, Piscaer TM, van Straten M, Booij R, Dijkshoorn ML, Kleinrensink GJ, Verhaar JA, Krestin GP, Weinans H, Oei EH.

Osteoarthritis Cartilage. 2012 Jul;20(7):678-85. doi: 10.1016/j.joca.2012.03.007. Epub 2012 Mar 21.


Pathophysiology of peri-articular bone changes in osteoarthritis.

Weinans H, Siebelt M, Agricola R, Botter SM, Piscaer TM, Waarsing JH.

Bone. 2012 Aug;51(2):190-6. doi: 10.1016/j.bone.2012.02.002. Epub 2012 Feb 11. Review.


Inhibition of Gsk3β in cartilage induces osteoarthritic features through activation of the canonical Wnt signaling pathway.

Miclea RL, Siebelt M, Finos L, Goeman JJ, Löwik CW, Oostdijk W, Weinans H, Wit JM, Robanus-Maandag EC, Karperien M.

Osteoarthritis Cartilage. 2011 Nov;19(11):1363-72. doi: 10.1016/j.joca.2011.07.014. Epub 2011 Aug 27.


Clinically applied CT arthrography to measure the sulphated glycosaminoglycan content of cartilage.

Siebelt M, van Tiel J, Waarsing JH, Piscaer TM, van Straten M, Booij R, Dijkshoorn ML, Kleinrensink GJ, Verhaar JA, Krestin GP, Weinans H, Oei EH.

Osteoarthritis Cartilage. 2011 Oct;19(10):1183-9. doi: 10.1016/j.joca.2011.07.006. Epub 2011 Jul 23.


Quantifying osteoarthritic cartilage changes accurately using in vivo microCT arthrography in three etiologically distinct rat models.

Siebelt M, Waarsing JH, Kops N, Piscaer TM, Verhaar JA, Oei EH, Weinans H.

J Orthop Res. 2011 Nov;29(11):1788-94. doi: 10.1002/jor.21444. Epub 2011 Apr 25.

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