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Items: 1 to 20 of 320


Malaria parasite CelTOS targets the inner leaflet of cell membranes for pore-dependent disruption.

Jimah JR, Salinas ND, Sala-Rabanal M, Jones NG, Sibley LD, Nichols CG, Schlesinger PH, Tolia NH.

Elife. 2016 Dec 1;5. pii: e20621. doi: 10.7554/eLife.20621.


Alternative BCG delivery strategies improve protection against Mycobacterium tuberculosis in non-human primates: Protection associated with mycobacterial antigen-specific CD4 effector memory T-cell populations.

Sharpe S, White A, Sarfas C, Sibley L, Gleeson F, McIntyre A, Basaraba R, Clark S, Hall G, Rayner E, Williams A, Marsh PD, Dennis M.

Tuberculosis (Edinb). 2016 Dec;101:174-190. doi: 10.1016/


Development of CRISPR/Cas9 for Efficient Genome Editing in Toxoplasma gondii.

Shen B, Brown K, Long S, Sibley LD.

Methods Mol Biol. 2017;1498:79-103.


A precise method to determine the activity of a weak neutron source using a germanium detector.

Duke MJ, Hallin AL, Krauss CB, Mekarski P, Sibley L.

Appl Radiat Isot. 2016 Oct;116:51-6. doi: 10.1016/j.apradiso.2016.06.032.


Perinatal Mortality Magnitude, Determinants and Causes in West Gojam: Population-Based Nested Case-Control Study.

Yirgu R, Molla M, Sibley L, Gebremariam A.

PLoS One. 2016 Jul 28;11(7):e0159390. doi: 10.1371/journal.pone.0159390.


Secreted protein kinases regulate cyst burden during chronic toxoplasmosis.

Jones NG, Wang Q, Sibley LD.

Cell Microbiol. 2017 Feb;19(2). doi: 10.1111/cmi.12651.


Toxoplasma Effector Recruits the Mi-2/NuRD Complex to Repress STAT1 Transcription and Block IFN-γ-Dependent Gene Expression.

Olias P, Etheridge RD, Zhang Y, Holtzman MJ, Sibley LD.

Cell Host Microbe. 2016 Jul 13;20(1):72-82. doi: 10.1016/j.chom.2016.06.006.


Identification of small molecule inhibitors that block the Toxoplasma gondii rhoptry kinase ROP18.

Simpson C, Jones NG, Hull-Ryde EA, Kireev D, Stashko M, Tang K, Janetka J, Wildman SA, Zuercher WJ, Schapira M, Hui R, Janzen W, Sibley LD.

ACS Infect Dis. 2016 Mar 11;2(3):194-206.


Genetic Mapping of Pathogenesis Determinants in Toxoplasma gondii.

Behnke MS, Dubey JP, Sibley LD.

Annu Rev Microbiol. 2016 Sep 8;70:63-81. doi: 10.1146/annurev-micro-091014-104353.


Serum Albumin Stimulates Protein Kinase G-dependent Microneme Secretion in Toxoplasma gondii.

Brown KM, Lourido S, Sibley LD.

J Biol Chem. 2016 Apr 29;291(18):9554-65. doi: 10.1074/jbc.M115.700518.


Analysis of Noncanonical Calcium-Dependent Protein Kinases in Toxoplasma gondii by Targeted Gene Deletion Using CRISPR/Cas9.

Long S, Wang Q, Sibley LD.

Infect Immun. 2016 Apr 22;84(5):1262-73. doi: 10.1128/IAI.01173-15.


Local admixture of amplified and diversified secreted pathogenesis determinants shapes mosaic Toxoplasma gondii genomes.

Lorenzi H, Khan A, Behnke MS, Namasivayam S, Swapna LS, Hadjithomas M, Karamycheva S, Pinney D, Brunk BP, Ajioka JW, Ajzenberg D, Boothroyd JC, Boyle JP, Dardé ML, Diaz-Miranda MA, Dubey JP, Fritz HM, Gennari SM, Gregory BD, Kim K, Saeij JP, Su C, White MW, Zhu XQ, Howe DK, Rosenthal BM, Grigg ME, Parkinson J, Liu L, Kissinger JC, Roos DS, Sibley LD.

Nat Commun. 2016 Jan 7;7:10147. doi: 10.1038/ncomms10147.


Route of delivery to the airway influences the distribution of pulmonary disease but not the outcome of Mycobacterium tuberculosis infection in rhesus macaques.

Sibley L, Dennis M, Sarfas C, White A, Clark S, Gleeson F, McIntyre A, Rayner E, Pearson G, Williams A, Marsh P, Sharpe S.

Tuberculosis (Edinb). 2016 Jan;96:141-9. doi: 10.1016/


Inhibition of Calcium-Dependent Protein Kinase 1 (CDPK1) In Vitro by Pyrazolopyrimidine Derivatives Does Not Correlate with Sensitivity of Cryptosporidium parvum Growth in Cell Culture.

Kuhlenschmidt TB, Rutaganira FU, Long S, Tang K, Shokat KM, Kuhlenschmidt MS, Sibley LD.

Antimicrob Agents Chemother. 2015 Nov 9;60(1):570-9. doi: 10.1128/AAC.01915-15.


A Noncanonical Autophagy Pathway Restricts Toxoplasma gondii Growth in a Strain-Specific Manner in IFN-γ-Activated Human Cells.

Selleck EM, Orchard RC, Lassen KG, Beatty WL, Xavier RJ, Levine B, Virgin HW, Sibley LD.

MBio. 2015 Sep 8;6(5):e01157-15. doi: 10.1128/mBio.01157-15.


Rhoptry Proteins ROP5 and ROP18 Are Major Murine Virulence Factors in Genetically Divergent South American Strains of Toxoplasma gondii.

Behnke MS, Khan A, Lauron EJ, Jimah JR, Wang Q, Tolia NH, Sibley LD.

PLoS Genet. 2015 Aug 20;11(8):e1005434. doi: 10.1371/journal.pgen.1005434.


Correction: Phosphorylation of Mouse Immunity-Related GTPase (IRG) Resistance Proteins Is an Evasion Strategy for Virulent Toxoplasma gondii.

Steinfeldt T, Könen-Waisman S, Tong L, Pawlowski N, Lamkemeyer T, Sibley LD, Hunn JP, Howard JC.

PLoS Biol. 2015 Jul 9;13(7):e1002199. doi: 10.1371/journal.pbio.1002199. No abstract available.


Reply to "reproducing increased dopamine with infection to evaluate the role of parasite-encoded tyrosine hydroxylase activity".

Wang ZT, Sibley LD.

Infect Immun. 2015 Aug;83(8):3336-7. doi: 10.1128/IAI.00642-15. No abstract available.


Evaluation of the Immunogenicity of Mycobacterium bovis BCG Delivered by Aerosol to the Lungs of Macaques.

White AD, Sarfas C, West K, Sibley LS, Wareham AS, Clark S, Dennis MJ, Williams A, Marsh PD, Sharpe SA.

Clin Vaccine Immunol. 2015 Sep;22(9):992-1003. doi: 10.1128/CVI.00289-15.

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