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Items: 1 to 20 of 155

1.

Kr├╝ppel-like Factor 5 Regulates Stemness, Lineage Specification, and Regeneration of Intestinal Epithelial Stem Cells.

Kim CK, Saxena M, Maharjan K, Song JJ, Shroyer KR, Bialkowska AB, Shivdasani RA, Yang VW.

Cell Mol Gastroenterol Hepatol. 2019 Nov 25. pii: S2352-345X(19)30164-X. doi: 10.1016/j.jcmgh.2019.11.009. [Epub ahead of print]

2.

Publisher Correction: Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors.

Cejas P, Drier Y, Dreijerink KMA, Brosens LAA, Deshpande V, Epstein CB, Conemans EB, Morsink FHM, Graham MK, Valk GD, Vriens MR, Castillo CF, Ferrone CR, Adar T, Bowden M, Whitton HJ, Da Silva A, Font-Tello A, Long HW, Gaskell E, Shoresh N, Heaphy CM, Sicinska E, Kulke MH, Chung DC, Bernstein BE, Shivdasani RA.

Nat Med. 2019 Oct;25(10):1627. doi: 10.1038/s41591-019-0573-5.

PMID:
31501535
3.

Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors.

Cejas P, Drier Y, Dreijerink KMA, Brosens LAA, Deshpande V, Epstein CB, Conemans EB, Morsink FHM, Graham MK, Valk GD, Vriens MR, Castillo CF, Ferrone CR, Adar T, Bowden M, Whitton HJ, Da Silva A, Font-Tello A, Long HW, Gaskell E, Shoresh N, Heaphy CM, Sicinska E, Kulke MH, Chung DC, Bernstein BE, Shivdasani RA.

Nat Med. 2019 Aug;25(8):1260-1265. doi: 10.1038/s41591-019-0493-4. Epub 2019 Jul 1. Erratum in: Nat Med. 2019 Oct;25(10):1627.

4.

Extensive Recovery of Embryonic Enhancer and Gene Memory Stored in Hypomethylated Enhancer DNA.

Jadhav U, Cavazza A, Banerjee KK, Xie H, O'Neill NK, Saenz-Vash V, Herbert Z, Madha S, Orkin SH, Zhai H, Shivdasani RA.

Mol Cell. 2019 May 2;74(3):542-554.e5. doi: 10.1016/j.molcel.2019.02.024. Epub 2019 Mar 21.

PMID:
30905509
5.

Dissecting Cell Lineages: From Microscope to Kaleidoscope.

Jadhav U, Shivdasani RA.

Cell. 2019 Feb 21;176(5):949-951. doi: 10.1016/j.cell.2019.01.054.

PMID:
30794779
6.

The lineage-specific transcription factor CDX2 navigates dynamic chromatin to control distinct stages of intestine development.

Kumar N, Tsai YH, Chen L, Zhou A, Banerjee KK, Saxena M, Huang S, Toke NH, Xing J, Shivdasani RA, Spence JR, Verzi MP.

Development. 2019 Mar 1;146(5). pii: dev172189. doi: 10.1242/dev.172189.

7.

TRPS1 Is a Lineage-Specific Transcriptional Dependency in Breast Cancer.

Witwicki RM, Ekram MB, Qiu X, Janiszewska M, Shu S, Kwon M, Trinh A, Frias E, Ramadan N, Hoffman G, Yu K, Xie Y, McAllister G, McDonald R, Golji J, Schlabach M, deWeck A, Keen N, Chan HM, Ruddy D, Rejtar T, Sovath S, Silver S, Sellers WR, Jagani Z, Hogarty MD, Roberts C, Brown M, Stegmaier K, Long H, Shivdasani RA, Pellman D, Polyak K.

Cell Rep. 2018 Oct 30;25(5):1255-1267.e5. doi: 10.1016/j.celrep.2018.10.023.

8.

Enhancer, transcriptional, and cell fate plasticity precedes intestinal determination during endoderm development.

Banerjee KK, Saxena M, Kumar N, Chen L, Cavazza A, Toke NH, O'Neill NK, Madha S, Jadhav U, Verzi MP, Shivdasani RA.

Genes Dev. 2018 Nov 1;32(21-22):1430-1442. doi: 10.1101/gad.318832.118. Epub 2018 Oct 26.

9.

Limited gut cell repertoire for multiple hormones.

Shivdasani RA.

Nat Cell Biol. 2018 Aug;20(8):865-867. doi: 10.1038/s41556-018-0153-9. No abstract available.

PMID:
30038256
10.

Transcription factor-dependent 'anti-repressive' mammalian enhancers exclude H3K27me3 from extended genomic domains.

Saxena M, Roman AKS, O'Neill NK, Sulahian R, Jadhav U, Shivdasani RA.

Genes Dev. 2017 Dec 1;31(23-24):2391-2404. doi: 10.1101/gad.308536.117. Epub 2018 Jan 10.

11.

Dynamic Reorganization of Chromatin Accessibility Signatures during Dedifferentiation of Secretory Precursors into Lgr5+ Intestinal Stem Cells.

Jadhav U, Saxena M, O'Neill NK, Saadatpour A, Yuan GC, Herbert Z, Murata K, Shivdasani RA.

Cell Stem Cell. 2017 Jul 6;21(1):65-77.e5. doi: 10.1016/j.stem.2017.05.001. Epub 2017 Jun 22.

12.

A Summary of the 2016 James W. Freston Conference of the American Gastroenterological Association: Intestinal Metaplasia in the Esophagus and Stomach: Origins, Differences, Similarities and Significance.

Spechler SJ, Merchant JL, Wang TC, Chandrasoma P, Fox JG, Genta RM, Goldenring JR, Hayakawa Y, Kuipers EJ, Lund PK, McKeon F, Mills JC, Odze RD, Peek RM Jr, Pham T, Que J, Rustgi AK, Shaheen NJ, Shivdasani RA, Souza RF, Storz P, Todisco A, Wang DH, Wright NA.

Gastroenterology. 2017 Jul;153(1):e6-e13. doi: 10.1053/j.gastro.2017.05.050. Epub 2017 Jun 3. No abstract available.

13.

Somatic copy number alterations in gastric adenocarcinomas among Asian and Western patients.

Schumacher SE, Shim BY, Corso G, Ryu MH, Kang YK, Roviello F, Saksena G, Peng S, Shivdasani RA, Bass AJ, Beroukhim R.

PLoS One. 2017 Apr 20;12(4):e0176045. doi: 10.1371/journal.pone.0176045. eCollection 2017.

14.

Natural Selection, Crypt Fitness, and Pol III Dependency in the Intestine.

Jadhav U, Shivdasani RA.

Cell Mol Gastroenterol Hepatol. 2016 Sep 26;2(6):714-715. doi: 10.1016/j.jcmgh.2016.09.006. eCollection 2016 Nov. No abstract available.

15.

ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice.

Mathur R, Alver BH, San Roman AK, Wilson BG, Wang X, Agoston AT, Park PJ, Shivdasani RA, Roberts CW.

Nat Genet. 2017 Feb;49(2):296-302. doi: 10.1038/ng.3744. Epub 2016 Dec 12.

16.

Transcriptional Regulator CNOT3 Defines an Aggressive Colorectal Cancer Subtype.

Cejas P, Cavazza A, Yandava CN, Moreno V, Horst D, Moreno-Rubio J, Burgos E, Mendiola M, Taing L, Goel A, Feliu J, Shivdasani RA.

Cancer Res. 2017 Feb 1;77(3):766-779. doi: 10.1158/0008-5472.CAN-16-1346. Epub 2016 Nov 29.

17.

Single-Cell Transcript Profiles Reveal Multilineage Priming in Early Progenitors Derived from Lgr5(+) Intestinal Stem Cells.

Kim TH, Saadatpour A, Guo G, Saxena M, Cavazza A, Desai N, Jadhav U, Jiang L, Rivera MN, Orkin SH, Yuan GC, Shivdasani RA.

Cell Rep. 2016 Aug 23;16(8):2053-2060. doi: 10.1016/j.celrep.2016.07.056. Epub 2016 Aug 11.

18.

Sox2 Suppresses Gastric Tumorigenesis in Mice.

Sarkar A, Huebner AJ, Sulahian R, Anselmo A, Xu X, Flattery K, Desai N, Sebastian C, Yram MA, Arnold K, Rivera M, Mostoslavsky R, Bronson R, Bass AJ, Sadreyev R, Shivdasani RA, Hochedlinger K.

Cell Rep. 2016 Aug 16;16(7):1929-41. doi: 10.1016/j.celrep.2016.07.034. Epub 2016 Aug 4.

19.

NF-E2, FLI1 and RUNX1 collaborate at areas of dynamic chromatin to activate transcription in mature mouse megakaryocytes.

Zang C, Luyten A, Chen J, Liu XS, Shivdasani RA.

Sci Rep. 2016 Jul 26;6:30255. doi: 10.1038/srep30255.

20.

Co-culture of Gastric Organoids and Immortalized Stomach Mesenchymal Cells.

Bertaux-Skeirik N, Centeno J, Feng R, Schumacher MA, Shivdasani RA, Zavros Y.

Methods Mol Biol. 2016;1422:23-31. doi: 10.1007/978-1-4939-3603-8_3.

PMID:
27246019

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