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Diabetogenic activity of 20 kDa human growth hormone (20K-hGH) and 22K-hGH in rats.
Takahashi S, Shiga Y, Satozawa N, Hayakawa M. Takahashi S, et al. Growth Horm IGF Res. 2001 Apr;11(2):110-6. doi: 10.1054/ghir.2001.0198. Growth Horm IGF Res. 2001. PMID: 11472077
A 24 h infusion of 20K-hGH had no significant effects on the GIR, R(d), HGO and R(g)(')except for in gastrocnemius muscle. In contrast, 22K-hGH significantly lowered the GIR compared with the control (P< 0.001) and 20K-hGH groups (P< 0.01). The infusion of 22K …
A 24 h infusion of 20K-hGH had no significant effects on the GIR, R(d), HGO and R(g)(')except for in gastrocnemius muscle. In contras …
Assessment of Adhesins as an Indicator of Pathovar-Associated Virulence Factors in Bovine Escherichia coli.
Valat C, Forest K, Auvray F, Métayer V, Méheut T, Polizzi C, Gay E, Haenni M, Oswald E, Madec JY. Valat C, et al. Appl Environ Microbiol. 2014 Dec;80(23):7230-4. doi: 10.1128/AEM.02365-14. Epub 2014 Sep 12. Appl Environ Microbiol. 2014. PMID: 25217019 Free PMC article.
A 79% to 82.4% correspondence between the two methods was found for fimbrial adhesins, whereas major discrepancies (33%) were observed for CS31A-type antigens. Various F17A variants were found, such as F17Ac (20K) (50%), F17Aa (FY) (18.9%), F17Ab (8.1%), and F17Ad (111K) ( …
A 79% to 82.4% correspondence between the two methods was found for fimbrial adhesins, whereas major discrepancies (33%) were observed for C …
Development of poly(ethylene glycol) conjugated lactoferrin for oral administration.
Nojima Y, Suzuki Y, Iguchi K, Shiga T, Iwata A, Fujimoto T, Yoshida K, Shimizu H, Takeuchi T, Sato A. Nojima Y, et al. Bioconjug Chem. 2008 Nov 19;19(11):2253-9. doi: 10.1021/bc800258v. Bioconjug Chem. 2008. PMID: 18834167
Therefore, to improve stability, we developed mono-PEGylated bovine LF (20k-PEG-bLf) with branched 20 kDa (2 x 10 kDa) poly(ethylene glycol) (PEG). ...Intravenous injection of the protein (1 mg/kg) revealed that 20k-PEG-bLf prolongs serum half-life by approximately …
Therefore, to improve stability, we developed mono-PEGylated bovine LF (20k-PEG-bLf) with branched 20 kDa (2 x 10 kDa) poly(ethylene …