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Items: 1 to 20 of 33


Uncovering synthetic lethal interactions for therapeutic targets and predictive markers in lung adenocarcinoma.

Chang JG, Chen CC, Wu YY, Che TF, Huang YS, Yeh KT, Shieh GS, Yang PC.

Oncotarget. 2016 Nov 8;7(45):73664-73680. doi: 10.18632/oncotarget.12046.


Chemotherapeutics-induced Oct4 expression contributes to drug resistance and tumor recurrence in bladder cancer.

Lu CS, Shieh GS, Wang CT, Su BH, Su YC, Chen YC, Su WC, Wu P, Yang WH, Shiau AL, Wu CL.

Oncotarget. 2017 May 9;8(19):30844-30858. doi: 10.18632/oncotarget.9602.


Etoposide enhances antitumor efficacy of MDR1-driven oncolytic adenovirus through autoupregulation of the MDR1 promoter activity.

Su BH, Shieh GS, Tseng YL, Shiau AL, Wu CL.

Oncotarget. 2015 Nov 10;6(35):38308-26. doi: 10.18632/oncotarget.5702.


Over-expression of prothymosin-α antagonizes TGFβ signalling to promote the development of emphysema.

Su BH, Tseng YL, Shieh GS, Chen YC, Wu P, Shiau AL, Wu CL.

J Pathol. 2016 Feb;238(3):412-22. doi: 10.1002/path.4664. Epub 2015 Nov 28.


The Overexpression of FEN1 and RAD54B May Act as Independent Prognostic Factors of Lung Adenocarcinoma.

Hwang JC, Sung WW, Tu HP, Hsieh KC, Yeh CM, Chen CJ, Tai HC, Hsu CT, Shieh GS, Chang JG, Yeh KT, Liu TC.

PLoS One. 2015 Oct 2;10(10):e0139435. doi: 10.1371/journal.pone.0139435. eCollection 2015.


Kallistatin ameliorates influenza virus pathogenesis by inhibition of kallikrein-related peptidase 1-mediated cleavage of viral hemagglutinin.

Leu CH, Yang ML, Chung NH, Huang YJ, Su YC, Chen YC, Lin CC, Shieh GS, Chang MY, Wang SW, Chang Y, Chao J, Chao L, Wu CL, Shiau AL.

Antimicrob Agents Chemother. 2015 Sep;59(9):5619-30. doi: 10.1128/AAC.00065-15. Epub 2015 Jul 6.


Potent antitumor activity of Oct4 and hypoxia dual-regulated oncolytic adenovirus against bladder cancer.

Lu CS, Hsieh JL, Lin CY, Tsai HW, Su BH, Shieh GS, Su YC, Lee CH, Chang MY, Wu CL, Shiau AL.

Gene Ther. 2015 Apr;22(4):305-15. doi: 10.1038/gt.2014.122. Epub 2015 Jan 15.


Zhankuic acid A as a novel JAK2 inhibitor for the treatment of concanavalin A-induced hepatitis.

Chen YF, Wang SH, Chang SJ, Shiau AL, Her LS, Shieh GS, Chen CF, Chang CC, Su YC, Wu CL, Wu TS.

Biochem Pharmacol. 2014 Sep 15;91(2):217-30. doi: 10.1016/j.bcp.2014.06.026. Epub 2014 Jul 27.


CSNK1E/CTNNB1 are synthetic lethal to TP53 in colorectal cancer and are markers for prognosis.

Tiong KL, Chang KC, Yeh KT, Liu TY, Wu JH, Hsieh PH, Lin SH, Lai WY, Hsu YC, Chen JY, Chang JG, Shieh GS.

Neoplasia. 2014 May;16(5):441-50. doi: 10.1016/j.neo.2014.04.007. Epub 2014 Jun 17.


Prothymosin α overexpression contributes to the development of pulmonary emphysema.

Su BH, Tseng YL, Shieh GS, Chen YC, Shiang YC, Wu P, Li KJ, Yen TH, Shiau AL, Wu CL.

Nat Commun. 2013;4:1906. doi: 10.1038/ncomms2906.


Inferring coregulation of transcription factors and microRNAs in breast cancer.

Wu JH, Sun YJ, Hsieh PH, Shieh GS.

Gene. 2013 Apr 10;518(1):139-44. doi: 10.1016/j.gene.2012.11.056. Epub 2012 Dec 14.


Inferring Genetic Interactions via a Data-Driven Second Order Model.

Jiang CR, Hung YC, Chen CM, Shieh GS.

Front Genet. 2012 May 3;3:71. doi: 10.3389/fgene.2012.00071. eCollection 2012.


Acquisition of an enhanced aggressive phenotype in human lung cancer cells selected by suboptimal doses of cisplatin following cell deattachment and reattachment.

Hsieh JL, Lu CS, Huang CL, Shieh GS, Su BH, Su YC, Lee CH, Chang MY, Wu CL, Shiau AL.

Cancer Lett. 2012 Aug 1;321(1):36-44. doi: 10.1016/j.canlet.2012.03.019. Epub 2012 Mar 23.


H2B ubiquitylation is part of chromatin architecture that marks exon-intron structure in budding yeast.

Shieh GS, Pan CH, Wu JH, Sun YJ, Wang CC, Hsiao WC, Lin CY, Tung L, Chang TH, Fleming AB, Hillyer C, Lo YC, Berger SL, Osley MA, Kao CF.

BMC Genomics. 2011 Dec 22;12:627. doi: 10.1186/1471-2164-12-627.


Identification of the common regulators for hepatocellular carcinoma induced by hepatitis B virus X antigen in a mouse model.

Lu JW, Hsia Y, Yang WY, Lin YI, Li CC, Tsai TF, Chang KW, Shieh GS, Tsai SF, Wang HD, Yuh CH.

Carcinogenesis. 2012 Jan;33(1):209-19. doi: 10.1093/carcin/bgr224. Epub 2011 Oct 21.


Galectin-1 binds to influenza virus and ameliorates influenza virus pathogenesis.

Yang ML, Chen YH, Wang SW, Huang YJ, Leu CH, Yeh NC, Chu CY, Lin CC, Shieh GS, Chen YL, Wang JR, Wang CH, Wu CL, Shiau AL.

J Virol. 2011 Oct;85(19):10010-20. doi: 10.1128/JVI.00301-11. Epub 2011 Jul 27.


Modeling and comparing the organization of circular genomes.

Shieh GS, Zheng S, Johnson RA, Chang YF, Shimizu K, Wang CC, Tang SL.

Bioinformatics. 2011 Apr 1;27(7):912-8. doi: 10.1093/bioinformatics/btr049. Epub 2011 Jan 28.


Sprouty2 protein enhances the response to gefitinib through epidermal growth factor receptor in colon cancer cells.

Feng YH, Tsao CJ, Wu CL, Chang JG, Lu PJ, Yeh KT, Shieh GS, Shiau AL, Lee JC.

Cancer Sci. 2010 Sep;101(9):2033-8. doi: 10.1111/j.1349-7006.2010.01637.x.


Inferring genetic interactions via a nonlinear model and an optimization algorithm.

Chen CM, Lee C, Chuang CL, Wang CC, Shieh GS.

BMC Syst Biol. 2010 Feb 26;4:16. doi: 10.1186/1752-0509-4-16.


WebPARE: web-computing for inferring genetic or transcriptional interactions.

Chuang CL, Wu JH, Cheng CS, Shieh GS.

Bioinformatics. 2010 Feb 15;26(4):582-4. doi: 10.1093/bioinformatics/btp684. Epub 2009 Dec 10.

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