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Items: 1 to 20 of 288

1.

Association of Tumor HER3 Messenger RNA Expression With Panitumumab Efficacy in Advanced Colorectal Cancer.

Seligmann JF, Hatch AJ, Richman SD, Elliott F, Jacobs B, Brown S, Hurwitz H, Barrett JH, Quirke P, Nixon AB, Seymour MT.

JAMA Oncol. 2017 Oct 26. doi: 10.1001/jamaoncol.2017.3168. [Epub ahead of print]

PMID:
29075780
2.

Decoy receptor 1 (DCR1) promoter hypermethylation and response to irinotecan in metastatic colorectal cancer.

Bosch LJW, Trooskens G, Snaebjornsson P, Coupé VMH, Mongera S, Haan JC, Richman SD, Koopman M, Tol J, de Meyer T, Louwagie J, Dehaspe L, van Grieken NCT, Ylstra B, Verheul HMW, van Engeland M, Nagtegaal ID, Herman JG, Quirke P, Seymour MT, Punt CJA, van Criekinge W, Carvalho B, Meijer GA.

Oncotarget. 2017 Jun 27;8(38):63140-63154. doi: 10.18632/oncotarget.18702. eCollection 2017 Sep 8.

3.

Environmental DNA metabarcoding: Transforming how we survey animal and plant communities.

Deiner K, Bik HM, Mächler E, Seymour M, Lacoursière-Roussel A, Altermatt F, Creer S, Bista I, Lodge DM, de Vere N, Pfrender ME, Bernatchez L.

Mol Ecol. 2017 Nov;26(21):5872-5895. doi: 10.1111/mec.14350. Epub 2017 Oct 26. Review.

PMID:
28921802
4.

Impact of tumour histological subtype on chemotherapy outcome in advanced oesophageal cancer.

Davidson M, Chau I, Cunningham D, Khabra K, Iveson T, Hickish T, Seymour M, Starling N.

World J Gastrointest Oncol. 2017 Aug 15;9(8):333-340. doi: 10.4251/wjgo.v9.i8.333.

5.

PDA PAC iAM 2017 Survey on Post Approval Change: Is the Regulatory Environment Hindering Much-Needed Innovation in the Pharma Industry?

Authors: Members of the PDA Task Force Post Approval Changes for Innovation in Availability of Medicines (PAC iAM), Ramnarine E, Busse U, Colao M, Edwards J, Follman K, Gale K, Good K, Kiani S, Jornitz M, Munk M, O'Donnel K, Seymour M, Simianu M, Skeens L, Vinther A, Baker D, Levy R.

PDA J Pharm Sci Technol. 2017 Sep-Oct;71(5):421-427. doi: 10.5731/pdajpst.2017.008219. Epub 2017 Aug 17. No abstract available.

PMID:
28819050
6.

Marine ecology: Genetics from a drop in the ocean.

Creer S, Seymour M.

Nat Ecol Evol. 2017 Jan 4;1(1):37. doi: 10.1038/s41559-016-0037. No abstract available.

PMID:
28812550
7.
8.

Bio-ecological factors associated with the psychological distress of fathers of children with autism spectrum disorder: A population-based study of Australian families.

Seymour M, Giallo R, Wood CE.

Autism. 2017 Jul 1:1362361317709971. doi: 10.1177/1362361317709971. [Epub ahead of print]

PMID:
28750543
9.

Intra-tumoural stromal morphometry predicts disease recurrence but not response to 5-fluorouracil - results from the QUASAR trial of colorectal cancer.

Hutchins GGA, Treanor D, Wright A, Handley K, Magill L, Tinkler-Hundal E, Southward K, Seymour M, Kerr D, Gray R, Quirke P; QUASAR trial collaborators the UK National Cancer Research Institute Colorectal Cancer Clinical Studies Group.

Histopathology. 2017 Jul 26. doi: 10.1111/his.13326. [Epub ahead of print]

PMID:
28746977
10.

An Atoh1-S193A Phospho-Mutant Allele Causes Hearing Deficits and Motor Impairment.

Xie WR, Jen HI, Seymour ML, Yeh SY, Pereira FA, Groves AK, Klisch TJ, Zoghbi HY.

J Neurosci. 2017 Sep 6;37(36):8583-8594. doi: 10.1523/JNEUROSCI.0295-17.2017. Epub 2017 Jul 20.

PMID:
28729444
11.

Corrigendum: mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases.

Palmieri M, Pal R, Nelvagal HR, Lotfi P, Stinnett GR, Seymour ML, Chaudhury A, Bajaj L, Bondar VV, Bremner L, Saleem U, Tse DY, Sanagasetti D, Wu SM, Neilson JR, Pereira FA, Pautler RG, Rodney GG, Cooper JD, Sardiello M.

Nat Commun. 2017 Jun 13;8:15793. doi: 10.1038/ncomms15793.

12.

Dynamic species classification of microorganisms across time, abiotic and biotic environments-A sliding window approach.

Pennekamp F, Griffiths JI, Fronhofer EA, Garnier A, Seymour M, Altermatt F, Petchey OL.

PLoS One. 2017 May 4;12(5):e0176682. doi: 10.1371/journal.pone.0176682. eCollection 2017.

13.

Clinical Calculator for Early Mortality in Metastatic Colorectal Cancer: An Analysis of Patients From 28 Clinical Trials in the Aide et Recherche en Cancérologie Digestive Database.

Renfro LA, Goldberg RM, Grothey A, Sobrero A, Adams R, Seymour MT, Heinemann V, Schmoll HJ, Douillard JY, Hurwitz H, Fuchs CS, Diaz-Rubio E, Porschen R, Tournigand C, Chibaudel B, Hoff PM, Kabbinavar FF, Falcone A, Tebbutt NC, Punt CJA, Hecht JR, Souglakos J, Bokemeyer C, Van Cutsem E, Saltz L, de Gramont A, Sargent DJ; ARCAD Clinical Trials Program.

J Clin Oncol. 2017 Jun 10;35(17):1929-1937. doi: 10.1200/JCO.2016.71.5771. Epub 2017 Apr 17.

PMID:
28414610
14.

Use of Gene Expression Profiles to Distinguish Molecular Subtypes in Colorectal Cancer: Progression Toward Primetime.

Seligmann JF, Seymour MT.

J Natl Cancer Inst. 2017 Jul 1;109(7). doi: 10.1093/jnci/djx019. No abstract available.

PMID:
28376180
15.

Single-crystal X-ray diffraction and NMR crystallography of a 1:1 cocrystal of dithianon and pyrimethanil.

Pöppler AC, Corlett EK, Pearce H, Seymour MP, Reid M, Montgomery MG, Brown SP.

Acta Crystallogr C Struct Chem. 2017 Mar 1;73(Pt 3):149-156. doi: 10.1107/S2053229617000870. Epub 2017 Feb 6.

16.

PDA Points to Consider: Technical Product Lifecycle Management. Pharmaceutical Quality System Effectiveness for Managing Post-approval Changes.

Authors: Members of the PDA Task Force on Post-approval Changes for Innovation in Availability of Medicines (PAC iAMsm), Ramnarine E, Busse U, Colao M, Edwards J, O'Donnell K, Jornitz M, Munk M, Seymour M, Simianu M, Skeens L, Vinther A.

PDA J Pharm Sci Technol. 2017 May-Jun;71(3):252-258. doi: 10.5731/pdajpst.2017.007575. Epub 2017 Feb 14. No abstract available.

PMID:
28196929
17.

Unilateral facial swelling in a thyrotoxic patient.

Seymour M, Morton A.

BMJ. 2017 Feb 9;356:j534. doi: 10.1136/bmj.j534. No abstract available.

PMID:
28183855
18.

mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases.

Palmieri M, Pal R, Nelvagal HR, Lotfi P, Stinnett GR, Seymour ML, Chaudhury A, Bajaj L, Bondar VV, Bremner L, Saleem U, Tse DY, Sanagasetti D, Wu SM, Neilson JR, Pereira FA, Pautler RG, Rodney GG, Cooper JD, Sardiello M.

Nat Commun. 2017 Feb 6;8:14338. doi: 10.1038/ncomms14338. Erratum in: Nat Commun. 2017 Jun 13;8:15793.

19.

Annual time-series analysis of aqueous eDNA reveals ecologically relevant dynamics of lake ecosystem biodiversity.

Bista I, Carvalho GR, Walsh K, Seymour M, Hajibabaei M, Lallias D, Christmas M, Creer S.

Nat Commun. 2017 Jan 18;8:14087. doi: 10.1038/ncomms14087.

20.

A randomised phase II trial and feasibility study of palliative chemotherapy in frail or elderly patients with advanced gastroesophageal cancer (321GO).

Hall PS, Lord SR, Collinson M, Marshall H, Jones M, Lowe C, Howard H, Swinson D, Velikova G, Anthoney A, Roy R, Dent J, Cheeseman S, Last K, Seymour MT.

Br J Cancer. 2017 Feb 14;116(4):472-478. doi: 10.1038/bjc.2016.442. Epub 2017 Jan 17.

PMID:
28095397

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