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Items: 1 to 20 of 21


Dutch Resolution of a configurationally stable [5]helquat.

Severa L, Sázelová P, Císařová I, Šaman D, Koval D, Devadig P, Kašička V, Teplý F.

Chirality. 2018 Jan 2. doi: 10.1002/chir.22789. [Epub ahead of print]


Effects of Once-Weekly Exenatide on Cardiovascular Outcomes in Type 2 Diabetes.

Holman RR, Bethel MA, Mentz RJ, Thompson VP, Lokhnygina Y, Buse JB, Chan JC, Choi J, Gustavson SM, Iqbal N, Maggioni AP, Marso SP, Öhman P, Pagidipati NJ, Poulter N, Ramachandran A, Zinman B, Hernandez AF; EXSCEL Study Group.

N Engl J Med. 2017 Sep 28;377(13):1228-1239. doi: 10.1056/NEJMoa1612917. Epub 2017 Sep 14.


Tunable Chiral Second-Order Nonlinear Optical Chromophores Based on Helquat Dications.

Buckley LER, Coe BJ, Rusanova D, Joshi VD, Sánchez S, Jirásek M, Vávra J, Khobragade D, Severa L, Císařová I, Šaman D, Pohl R, Clays K, Depotter G, Brunschwig BS, Teplý F.

J Phys Chem A. 2017 Aug 10;121(31):5842-5855. doi: 10.1021/acs.jpca.7b06057. Epub 2017 Jul 31.


Efficacy and Safety of Degludec versus Glargine in Type 2 Diabetes.

Marso SP, McGuire DK, Zinman B, Poulter NR, Emerson SS, Pieber TR, Pratley RE, Haahr PM, Lange M, Brown-Frandsen K, Moses A, Skibsted S, Kvist K, Buse JB; DEVOTE Study Group.

N Engl J Med. 2017 Aug 24;377(8):723-732. doi: 10.1056/NEJMoa1615692. Epub 2017 Jun 12.


Chiral analysis of α-diimine Ru(II) and Fe(II) complexes by capillary electrophoresis using sulfated cyclodextrins as stereoselectors.

Sázelová P, Koval D, Severa L, Teplý F, Kašička V.

Electrophoresis. 2017 Aug;38(15):1913-1921. doi: 10.1002/elps.201700077. Epub 2017 May 11.


Helquat Dyes: Helicene-like Push-Pull Systems with Large Second-Order Nonlinear Optical Responses.

Coe BJ, Rusanova D, Joshi VD, Sánchez S, Vávra J, Khobragade D, Severa L, Císařová I, Šaman D, Pohl R, Clays K, Depotter G, Brunschwig BS, Teplý F.

J Org Chem. 2016 Mar 4;81(5):1912-20. doi: 10.1021/acs.joc.5b02692. Epub 2016 Feb 19.


Single-Crystal-to-Single-Crystal Transition in an Enantiopure [7]Helquat Salt: The First Observation of a Reversible Phase Transition in a Helicene-Like Compound.

Nath NK, Severa L, Kunetskiy RA, Císařová I, Fulem M, Růžička K, Koval D, Kašička V, Teplý F, Naumov P.

Chemistry. 2015 Sep 21;21(39):13508-12. doi: 10.1002/chem.201502094. Epub 2015 Aug 12.


Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes.

Cannon CP, Blazing MA, Giugliano RP, McCagg A, White JA, Theroux P, Darius H, Lewis BS, Ophuis TO, Jukema JW, De Ferrari GM, Ruzyllo W, De Lucca P, Im K, Bohula EA, Reist C, Wiviott SD, Tershakovec AM, Musliner TA, Braunwald E, Califf RM; IMPROVE-IT Investigators.

N Engl J Med. 2015 Jun 18;372(25):2387-97. doi: 10.1056/NEJMoa1410489. Epub 2015 Jun 3.


Long-term use of ticagrelor in patients with prior myocardial infarction.

Bonaca MP, Bhatt DL, Cohen M, Steg PG, Storey RF, Jensen EC, Magnani G, Bansilal S, Fish MP, Im K, Bengtsson O, Oude Ophuis T, Budaj A, Theroux P, Ruda M, Hamm C, Goto S, Spinar J, Nicolau JC, Kiss RG, Murphy SA, Wiviott SD, Held P, Braunwald E, Sabatine MS; PEGASUS-TIMI 54 Steering Committee and Investigators.

N Engl J Med. 2015 May 7;372(19):1791-800. doi: 10.1056/NEJMoa1500857. Epub 2015 Mar 14.


Functional helquats: helical cationic dyes with marked, switchable chiroptical properties in the visible region.

Reyes-Gutiérrez PE, Jirásek M, Severa L, Novotná P, Koval D, Sázelová P, Vávra J, Meyer A, Císařová I, Šaman D, Pohl R, Štěpánek P, Slavíček P, Coe BJ, Hájek M, Kašička V, Urbanová M, Teplý F.

Chem Commun (Camb). 2015 Jan 31;51(9):1583-6. doi: 10.1039/c4cc08967g.


Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease.

Salloway S, Sperling R, Fox NC, Blennow K, Klunk W, Raskind M, Sabbagh M, Honig LS, Porsteinsson AP, Ferris S, Reichert M, Ketter N, Nejadnik B, Guenzler V, Miloslavsky M, Wang D, Lu Y, Lull J, Tudor IC, Liu E, Grundman M, Yuen E, Black R, Brashear HR; Bapineuzumab 301 and 302 Clinical Trial Investigators.

N Engl J Med. 2014 Jan 23;370(4):322-33. doi: 10.1056/NEJMoa1304839.


Helquat-induced chiroselective aggregation of Au NPs.

Balogh D, Zhang Z, Cecconello A, Vavra J, Severa L, Teply F, Willner I.

Nano Lett. 2012 Nov 14;12(11):5835-9. doi: 10.1021/nl303179s. Epub 2012 Oct 15.


A chiral dicationic [8]circulenoid: photochemical origin and facile thermal conversion into a helicene congener.

Severa L, Ončák M, Koval D, Pohl R, Saman D, Císařová I, Reyes-Gutiérrez PE, Sázelová P, Kašička V, Teplý F, Slavíček P.

Angew Chem Int Ed Engl. 2012 Nov 26;51(48):11972-6. doi: 10.1002/anie.201203562. Epub 2012 Sep 28. No abstract available.


Search for conglomerate in set of [7]helquat salts: multigram resolution of helicene-viologen hybrid by preferential crystallization.

Vávra J, Severa L, Císařová I, Klepetářová B, Šaman D, Koval D, Kašička V, Teplý F.

J Org Chem. 2013 Feb 15;78(4):1329-42. doi: 10.1021/jo301615k. Epub 2012 Sep 24.


Can hindered intramolecular vibrational energy redistribution lead to non-ergodic behavior of medium-sized ion pairs?

Shaffer CJ, Révész Á, Schröder D, Severa L, Teplý F, Zins EL, Jašíková L, Roithová J.

Angew Chem Int Ed Engl. 2012 Oct 1;51(40):10050-3. doi: 10.1002/anie.201203441. Epub 2012 Aug 15. No abstract available.


Efficacy and safety of exenatide once weekly versus metformin, pioglitazone, and sitagliptin used as monotherapy in drug-naive patients with type 2 diabetes (DURATION-4): a 26-week double-blind study.

Russell-Jones D, Cuddihy RM, Hanefeld M, Kumar A, González JG, Chan M, Wolka AM, Boardman MK; DURATION-4 Study Group.

Diabetes Care. 2012 Feb;35(2):252-8. doi: 10.2337/dc11-1107. Epub 2011 Dec 30.


Chiral analysis of helquats by capillary electrophoresis: resolution of helical N-heteroaromatic dications using randomly sulfated cyclodextrins.

Koval D, Severa L, Adriaenssens L, Vávra J, Teplý F, Kašička V.

Electrophoresis. 2011 Oct;32(19):2683-92. doi: 10.1002/elps.201100173. Epub 2011 Sep 12.


Helquats, helical extended diquats, as fast electron transfer systems.

Pospísil L, Teplý F, Gál M, Adriaenssens L, Horácek M, Severa L.

Phys Chem Chem Phys. 2010 Feb 21;12(7):1550-6. doi: 10.1039/b915148f. Epub 2010 Jan 11.


Evaluation of shape variability of stallion sperm heads by means of image analysis and Fourier descriptors.

Severa L, Máchal L, Svábová L, Mamica O.

Anim Reprod Sci. 2010 May;119(1-2):50-5. doi: 10.1016/j.anireprosci.2009.12.007. Epub 2009 Dec 16.


Helquats: a facile, modular, scalable route to novel helical dications.

Adriaenssens L, Severa L, Sálová T, Císarová I, Pohl R, Saman D, Rocha SV, Finney NS, Pospísil L, Slavícek P, Teplý F.

Chemistry. 2009;15(5):1072-6. doi: 10.1002/chem.200801904. No abstract available.


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