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Items: 1 to 20 of 139

1.

Letter to Editor, International Journal of Pharmaceutics.

Seinen W, Brands R.

Int J Pharm. 2016 Apr 30;503(1-2):277-8. doi: 10.1016/j.ijpharm.2016.01.077. No abstract available.

PMID:
26874022
2.

Microdosing of a Carbon-14 Labeled Protein in Healthy Volunteers Accurately Predicts Its Pharmacokinetics at Therapeutic Dosages.

Vlaming ML, van Duijn E, Dillingh MR, Brands R, Windhorst AD, Hendrikse NH, Bosgra S, Burggraaf J, de Koning MC, Fidder A, Mocking JA, Sandman H, de Ligt RA, Fabriek BO, Pasman WJ, Seinen W, Alves T, Carrondo M, Peixoto C, Peeters PA, Vaes WH.

Clin Pharmacol Ther. 2015 Aug;98(2):196-204. doi: 10.1002/cpt.131.

PMID:
25869840
3.

An alkaline phosphatase transport mechanism in the pathogenesis of Alzheimer's disease and neurodegeneration.

Pike AF, Kramer NI, Blaauboer BJ, Seinen W, Brands R.

Chem Biol Interact. 2015 Jan 25;226:30-9. doi: 10.1016/j.cbi.2014.12.006. Review.

PMID:
25500268
4.

A novel hypothesis for an alkaline phosphatase 'rescue' mechanism in the hepatic acute phase immune response.

Pike AF, Kramer NI, Blaauboer BJ, Seinen W, Brands R.

Biochim Biophys Acta. 2013 Dec;1832(12):2044-56. doi: 10.1016/j.bbadis.2013.07.016.

5.

Prophylactic treatment with alkaline phosphatase in cardiac surgery induces endogenous alkaline phosphatase release.

Kats S, Brands R, Hamad MA, Seinen W, Scharnhorst V, Wulkan RW, Schönberger JP, Oeveren Wv.

Int J Artif Organs. 2012 Feb;35(2):144-51. doi: 10.5301/ijao.5000039.

PMID:
22395920
6.

Endotoxin release in cardiac surgery with cardiopulmonary bypass: pathophysiology and possible therapeutic strategies. An update.

Kats S, Schönberger JP, Brands R, Seinen W, van Oeveren W.

Eur J Cardiothorac Surg. 2011 Apr;39(4):451-8. doi: 10.1016/j.ejcts.2010.06.011. Review.

PMID:
20663682
7.

Anti-inflammatory effects of alkaline phosphatase in coronary artery bypass surgery with cardiopulmonary bypass.

Kats S, Brands R, Seinen W, de Jager W, Bekker MW, Hamad MA, Tan ME, Schönberger JP.

Recent Pat Inflamm Allergy Drug Discov. 2009 Nov;3(3):214-20. Review.

PMID:
19534671
8.

Safety and nutritional assessment of GM plants and derived food and feed: the role of animal feeding trials.

EFSA GMO Panel Working Group on Animal Feeding Trials..

Food Chem Toxicol. 2008 Mar;46 Suppl 1:S2-70. doi: 10.1016/j.fct.2008.02.008. Review.

PMID:
18328408
9.

Endocrine effects of polycyclic musks: do we smell a rat?

van der Burg B, Schreurs R, van der Linden S, Seinen W, Brouwer A, Sonneveld E.

Int J Androl. 2008 Apr;31(2):188-93. Review.

PMID:
17971161
10.

On the limits of toxicant-induced tolerance testing: cotolerance and response variation of antibiotic effects.

Schmitt H, Martinali B, Van Beelen P, Seinen W.

Environ Toxicol Chem. 2006 Jul;25(7):1961-8.

PMID:
16833161
11.

High level expression of tissue-nonspecific alkaline phosphatase in the milk of transgenic rabbits.

Bodrogi L, Brands R, Raaben W, Seinen W, Baranyi M, Fiechter D, Bosze Z.

Transgenic Res. 2006 Oct;15(5):627-36.

PMID:
16826424
12.

Effects of BPA in snails.

Dietrich DR, O'Brien E, Hoffmann S, Balaguer P, Nicolas JC, Seinen W, Depledge M.

Environ Health Perspect. 2006 Jun;114(6):A340-1; author reply A341-2. No abstract available.

13.

Tetracyclines and tetracycline resistance in agricultural soils: microcosm and field studies.

Schmitt H, Stoob K, Hamscher G, Smit E, Seinen W.

Microb Ecol. 2006 Apr;51(3):267-76.

PMID:
16598633
14.

The Impact of the hyperacid Ijen Crater Lake. Part II: A total diet study.

Heikens A, Widianarko B, Dewi IC, de Boer JL, Seinen W, van Leeuwen K.

Environ Geochem Health. 2005 Sep;27(5-6):475-83.

PMID:
16237603
15.

The impact of the hyperacid Ijen Crater Lake. Part I: Concentrations of elements in crops and soil.

Heikens A, Widianarko B, Dewi IC, De Boer JL, Seinen W, van Leeuwen K.

Environ Geochem Health. 2005 Sep;27(5-6):409-18.

PMID:
16237597
16.

Induction of ethoxy-resorufin-O-deethylase activity by halogenated aromatic hydrocarbons and polycyclic aromatic hydrocarbons in primary hepatocytes of the green frog (Rana esculenta).

Rankouhi TR, Koomen B, Sanderson JT, Bosveld AT, Seinen W, van den Berg M.

Environ Toxicol Chem. 2005 Jun;24(6):1428-35.

PMID:
16117119
17.

The impact of the hyperacid Ijen Crater Lake: risks of excess fluoride to human health.

Heikens A, Sumarti S, van Bergen M, Widianarko B, Fokkert L, van Leeuwen K, Seinen W.

Sci Total Environ. 2005 Jun 15;346(1-3):56-69.

PMID:
15993682
18.
19.

CP-arene oxides: the ultimate, active mutagenic forms of cyclopenta-fused polycyclic aromatic hydrocarbons (CP-PAHs).

Otero-Lobato MJ, Kaats-Richters VE, Koper C, Vlietstra EJ, Havenith RW, Jenneskens LW, Seinen W.

Mutat Res. 2005 Mar 7;581(1-2):115-32.

PMID:
15725611
20.

Proceedings in uncovering the mechanism behind peroxisome proliferator-induced hepatocarcinogenesis.

Bosgra S, Mennes W, Seinen W.

Toxicology. 2005 Jan 31;206(3):309-23. Review.

PMID:
15588922
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