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Items: 1 to 20 of 167

1.

Modeling and high-throughput experimental data uncover the mechanisms underlying Fshb gene sensitivity to gonadotropin-releasing hormone pulse frequency.

Stern E, Ruf-Zamojski F, Zalepa-King L, Pincas H, Choi SG, Peskin CS, Hayot F, Turgeon JL, Sealfon SC.

J Biol Chem. 2017 Jun 9;292(23):9815-9829. doi: 10.1074/jbc.M117.783886. Epub 2017 Apr 6.

PMID:
28385888
2.

Multiscale Modeling of Complex Formation and CD80 Depletion during Immune Synapse Development.

Sugár IP, Das J, Jayaprakash C, Sealfon SC.

Biophys J. 2017 Mar 14;112(5):997-1009. doi: 10.1016/j.bpj.2016.12.052.

PMID:
28297658
3.

Elucidation of molecular kinetic schemes from macroscopic traces using system identification.

Fribourg M, Logothetis DE, González-Maeso J, Sealfon SC, Galocha-Iragüen B, Las-Heras Andrés F, Brezina V.

PLoS Comput Biol. 2017 Feb 13;13(2):e1005376. doi: 10.1371/journal.pcbi.1005376. eCollection 2017 Feb.

4.

Solving Immunology?

Vodovotz Y, Xia A, Read EL, Bassaganya-Riera J, Hafler DA, Sontag E, Wang J, Tsang JS, Day JD, Kleinstein SH, Butte AJ, Altman MC, Hammond R, Sealfon SC.

Trends Immunol. 2017 Feb;38(2):116-127. doi: 10.1016/j.it.2016.11.006. Epub 2016 Dec 13. Review.

PMID:
27986392
5.

Characterization of Gonadotrope Secretoproteome Identifies Neurosecretory Protein VGF-derived Peptide Suppression of Follicle-stimulating Hormone Gene Expression.

Choi SG, Wang Q, Jia J, Chikina M, Pincas H, Dolios G, Sasaki K, Wang R, Minamino N, Salton SR, Sealfon SC.

J Biol Chem. 2016 Sep 30;291(40):21322-21334. Epub 2016 Jul 27.

PMID:
27466366
6.

RIPK3 Activates Parallel Pathways of MLKL-Driven Necroptosis and FADD-Mediated Apoptosis to Protect against Influenza A Virus.

Nogusa S, Thapa RJ, Dillon CP, Liedmann S, Oguin TH 3rd, Ingram JP, Rodriguez DA, Kosoff R, Sharma S, Sturm O, Verbist K, Gough PJ, Bertin J, Hartmann BM, Sealfon SC, Kaiser WJ, Mocarski ES, López CB, Thomas PG, Oberst A, Green DR, Balachandran S.

Cell Host Microbe. 2016 Jul 13;20(1):13-24. doi: 10.1016/j.chom.2016.05.011. Epub 2016 Jun 16.

7.

MOCCASIN: converting MATLAB ODE models to SBML.

Gómez HF, Hucka M, Keating SM, Nudelman G, Iber D, Sealfon SC.

Bioinformatics. 2016 Jun 15;32(12):1905-6. doi: 10.1093/bioinformatics/btw056. Epub 2016 Feb 9.

8.

Cross-signaling in metabotropic glutamate 2 and serotonin 2A receptor heteromers in mammalian cells.

Baki L, Fribourg M, Younkin J, Eltit JM, Moreno JL, Park G, Vysotskaya Z, Narahari A, Sealfon SC, Gonzalez-Maeso J, Logothetis DE.

Pflugers Arch. 2016 May;468(5):775-93. doi: 10.1007/s00424-015-1780-7. Epub 2016 Jan 16.

9.

Interactive Big Data Resource to Elucidate Human Immune Pathways and Diseases.

Gorenshteyn D, Zaslavsky E, Fribourg M, Park CY, Wong AK, Tadych A, Hartmann BM, Albrecht RA, García-Sastre A, Kleinstein SH, Troyanskaya OG, Sealfon SC.

Immunity. 2015 Sep 15;43(3):605-14. doi: 10.1016/j.immuni.2015.08.014. Epub 2015 Sep 8.

10.

Comparative analysis of anti-viral transcriptomics reveals novel effects of influenza immune antagonism.

Thakar J, Hartmann BM, Marjanovic N, Sealfon SC, Kleinstein SH.

BMC Immunol. 2015 Aug 14;16:46. doi: 10.1186/s12865-015-0107-y.

11.

Human Dendritic Cell Response Signatures Distinguish 1918, Pandemic, and Seasonal H1N1 Influenza Viruses.

Hartmann BM, Thakar J, Albrecht RA, Avey S, Zaslavsky E, Marjanovic N, Chikina M, Fribourg M, Hayot F, Schmolke M, Meng H, Wetmur J, García-Sastre A, Kleinstein SH, Sealfon SC.

J Virol. 2015 Oct;89(20):10190-205. doi: 10.1128/JVI.01523-15. Epub 2015 Jul 29.

12.

Understanding multicellular function and disease with human tissue-specific networks.

Greene CS, Krishnan A, Wong AK, Ricciotti E, Zelaya RA, Himmelstein DS, Zhang R, Hartmann BM, Zaslavsky E, Sealfon SC, Chasman DI, FitzGerald GA, Dolinski K, Grosser T, Troyanskaya OG.

Nat Genet. 2015 Jun;47(6):569-76. doi: 10.1038/ng.3259. Epub 2015 Apr 27.

13.

Low-variance RNAs identify Parkinson's disease molecular signature in blood.

Chikina MD, Gerald CP, Li X, Ge Y, Pincas H, Nair VD, Wong AK, Krishnan A, Troyanskaya OG, Raymond D, Saunders-Pullman R, Bressman SB, Yue Z, Sealfon SC.

Mov Disord. 2015 May;30(6):813-21. doi: 10.1002/mds.26205. Epub 2015 Mar 18.

14.

Single-cell analysis shows that paracrine signaling by first responder cells shapes the interferon-β response to viral infection.

Patil S, Fribourg M, Ge Y, Batish M, Tyagi S, Hayot F, Sealfon SC.

Sci Signal. 2015 Feb 10;8(363):ra16. doi: 10.1126/scisignal.2005728.

PMID:
25670204
15.

CellCODE: a robust latent variable approach to differential expression analysis for heterogeneous cell populations.

Chikina M, Zaslavsky E, Sealfon SC.

Bioinformatics. 2015 May 15;31(10):1584-91. doi: 10.1093/bioinformatics/btv015. Epub 2015 Jan 11.

16.

Hybrid Bayesian-rank integration approach improves the predictive power of genomic dataset aggregation.

Badgeley MA, Sealfon SC, Chikina MD.

Bioinformatics. 2015 Jan 15;31(2):209-15. doi: 10.1093/bioinformatics/btu518. Epub 2014 Sep 29.

17.

Growth differentiation factor 9 (GDF9) forms an incoherent feed-forward loop modulating follicle-stimulating hormone β-subunit (FSHβ) gene expression.

Choi SG, Wang Q, Jia J, Pincas H, Turgeon JL, Sealfon SC.

J Biol Chem. 2014 Jun 6;289(23):16164-75. doi: 10.1074/jbc.M113.537696. Epub 2014 Apr 28.

18.

Increasing consistency of disease biomarker prediction across datasets.

Chikina MD, Sealfon SC.

PLoS One. 2014 Apr 16;9(4):e91272. doi: 10.1371/journal.pone.0091272. eCollection 2014.

19.

Combinatorial cytokine code generates anti-viral state in dendritic cells.

Hartmann BM, Marjanovic N, Nudelman G, Moran TM, Sealfon SC.

Front Immunol. 2014 Feb 26;5:73. doi: 10.3389/fimmu.2014.00073. eCollection 2014.

20.

Model of influenza A virus infection: dynamics of viral antagonism and innate immune response.

Fribourg M, Hartmann B, Schmolke M, Marjanovic N, Albrecht RA, García-Sastre A, Sealfon SC, Jayaprakash C, Hayot F.

J Theor Biol. 2014 Jun 21;351:47-57. doi: 10.1016/j.jtbi.2014.02.029. Epub 2014 Mar 2.

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