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Items: 1 to 20 of 95

1.

Collagen prolyl hydroxylation-dependent metabolic perturbation governs epigenetic remodeling and mesenchymal transition in pluripotent and cancer cells.

D'Aniello C, Cermola F, Palamidessi A, Wanderlingh LG, Gagliardi M, Migliaccio A, Varrone F, Casalino L, Matarazzo MR, De Cesare D, Scita G, Patriarca EJ, Minchiotti G.

Cancer Res. 2019 May 6. pii: canres.2070.2018. doi: 10.1158/0008-5472.CAN-18-2070. [Epub ahead of print]

PMID:
31061065
2.

Local actin nucleation tunes centrosomal microtubule nucleation during passage through mitosis.

Farina F, Ramkumar N, Brown L, Samander-Eweis D, Anstatt J, Waring T, Bithell J, Scita G, Thery M, Blanchoin L, Zech T, Baum B.

EMBO J. 2019 Apr 23. pii: e99843. doi: 10.15252/embj.201899843. [Epub ahead of print]

3.

Frustration-induced phases in migrating cell clusters.

Copenhagen K, Malet-Engra G, Yu W, Scita G, Gov N, Gopinathan A.

Sci Adv. 2018 Sep 12;4(9):eaar8483. doi: 10.1126/sciadv.aar8483. eCollection 2018 Sep.

4.

A NUMB-EFA6B-ARF6 recycling route controls apically restricted cell protrusions and mesenchymal motility.

Zobel M, Disanza A, Senic-Matuglia F, Franco M, Colaluca IN, Confalonieri S, Bisi S, Barbieri E, Caldieri G, Sigismund S, Pece S, Chavrier P, Di Fiore PP, Scita G.

J Cell Biol. 2018 Sep 3;217(9):3161-3182. doi: 10.1083/jcb.201802023. Epub 2018 Jul 30.

5.

Inhibition of Cyclin-Dependent Kinase 5: A Strategy to Improve Sorafenib Response in Hepatocellular Carcinoma Therapy.

Ardelt MA, Fröhlich T, Martini E, Müller M, Kanitz V, Atzberger C, Cantonati P, Meßner M, Posselt L, Lehr T, Wojtyniak JG, Ulrich M, Arnold GJ, König L, Parazzoli D, Zahler S, Rothenfußer S, Mayr D, Gerbes A, Scita G, Vollmar AM, Pachmayr J.

Hepatology. 2019 Jan;69(1):376-393. doi: 10.1002/hep.30190. Epub 2018 Dec 22.

6.

Author Correction: A RAB35-p85/PI3K axis controls oscillatory apical protrusions required for efficient chemotactic migration.

Corallino S, Malinverno C, Neumann B, Tischer C, Palamidessi A, Frittoli E, Panagiotakopoulou M, Disanza A, Malet-Engra G, Nastaly P, Galli C, Luise C, Bertalot G, Pece S, Di Fiore PP, Gauthier N, Ferrari A, Maiuri P, Scita G.

Nat Commun. 2018 May 22;9(1):2085. doi: 10.1038/s41467-018-04515-y.

7.

Small GTPases and BAR domain proteins regulate branched actin polymerisation for clathrin and dynamin-independent endocytosis.

Sathe M, Muthukrishnan G, Rae J, Disanza A, Thattai M, Scita G, Parton RG, Mayor S.

Nat Commun. 2018 May 9;9(1):1835. doi: 10.1038/s41467-018-03955-w.

8.

From jamming to collective cell migration through a boundary induced transition.

Chepizhko O, Lionetti MC, Malinverno C, Giampietro C, Scita G, Zapperi S, La Porta CAM.

Soft Matter. 2018 May 16;14(19):3774-3782. doi: 10.1039/c8sm00128f.

PMID:
29713711
9.

Co-optation of Tandem DNA Repeats for the Maintenance of Mesenchymal Identity.

Balestrieri C, Alfarano G, Milan M, Tosi V, Prosperini E, Nicoli P, Palamidessi A, Scita G, Diaferia GR, Natoli G.

Cell. 2018 May 17;173(5):1150-1164.e14. doi: 10.1016/j.cell.2018.03.081. Epub 2018 Apr 26.

PMID:
29706544
10.

Flocking transitions in confluent tissues.

Giavazzi F, Paoluzzi M, Macchi M, Bi D, Scita G, Manning ML, Cerbino R, Marchetti MC.

Soft Matter. 2018 May 9;14(18):3471-3477. doi: 10.1039/c8sm00126j.

11.

A RAB35-p85/PI3K axis controls oscillatory apical protrusions required for efficient chemotactic migration.

Corallino S, Malinverno C, Neumann B, Tischer C, Palamidessi A, Frittoli E, Panagiotakopoulou M, Disanza A, Malet-Engra G, Nastaly P, Galli C, Luise C, Bertalot G, Pece S, Di Fiore PP, Gauthier N, Ferrari A, Maiuri P, Scita G.

Nat Commun. 2018 Apr 16;9(1):1475. doi: 10.1038/s41467-018-03571-8. Erratum in: Nat Commun. 2018 May 22;9(1):2085.

12.

The 'endocytic matrix reloaded' and its impact on the plasticity of migratory strategies.

Sigismund S, Scita G.

Curr Opin Cell Biol. 2018 Oct;54:9-17. doi: 10.1016/j.ceb.2018.02.006. Epub 2018 Mar 12. Review.

13.

Modulation of RAB5A early endosome trafficking in response to KRas mediated macropinocytic fluxes in pancreatic cancer cells.

Teske C, Schweitzer C, Palamidessi A, Aust DE, Scita G, Weitz J, Welsch T.

Biochem Biophys Res Commun. 2017 Nov 4;493(1):528-533. doi: 10.1016/j.bbrc.2017.08.157. Epub 2017 Sep 1.

PMID:
28867190
14.

Pro-migratory and TGF-β-activating functions of αvβ6 integrin in pancreatic cancer are differentially regulated via an Eps8-dependent GTPase switch.

Tod J, Hanley CJ, Morgan MR, Rucka M, Mellows T, Lopez MA, Kiely P, Moutasim KA, Frampton SJ, Sabnis D, Fine DR, Johnson C, Marshall JF, Scita G, Jenei V, Thomas GJ.

J Pathol. 2017 Sep;243(1):37-50. doi: 10.1002/path.4923. Epub 2017 Aug 7.

15.

Rab2 promotes autophagic and endocytic lysosomal degradation.

Lőrincz P, Tóth S, Benkő P, Lakatos Z, Boda A, Glatz G, Zobel M, Bisi S, Hegedűs K, Takáts S, Scita G, Juhász G.

J Cell Biol. 2017 Jul 3;216(7):1937-1947. doi: 10.1083/jcb.201611027. Epub 2017 May 8.

16.

Endocytic reawakening of motility in jammed epithelia.

Malinverno C, Corallino S, Giavazzi F, Bergert M, Li Q, Leoni M, Disanza A, Frittoli E, Oldani A, Martini E, Lendenmann T, Deflorian G, Beznoussenko GV, Poulikakos D, Haur OK, Uroz M, Trepat X, Parazzoli D, Maiuri P, Yu W, Ferrari A, Cerbino R, Scita G.

Nat Mater. 2017 May;16(5):587-596. doi: 10.1038/nmat4848. Epub 2017 Jan 30.

17.

Harnessing membrane trafficking to promote cancer spreading and invasion: The case of RAB2A.

Kajiho H, Kajiho Y, Scita G.

Small GTPases. 2018 Jul 4;9(4):304-309. doi: 10.1080/21541248.2016.1223990. Epub 2017 Jan 27. Review.

18.

Differential identity of Filopodia and Tunneling Nanotubes revealed by the opposite functions of actin regulatory complexes.

Delage E, Cervantes DC, Pénard E, Schmitt C, Syan S, Disanza A, Scita G, Zurzolo C.

Sci Rep. 2016 Dec 23;6:39632. doi: 10.1038/srep39632.

19.

SOS1, ARHGEF1, and DOCK2 rho-GEFs Mediate JAK-Dependent LFA-1 Activation by Chemokines.

Toffali L, Montresor A, Mirenda M, Scita G, Laudanna C.

J Immunol. 2017 Jan 15;198(2):708-717. doi: 10.4049/jimmunol.1600933. Epub 2016 Dec 16.

20.

Bursts of activity in collective cell migration.

Chepizhko O, Giampietro C, Mastrapasqua E, Nourazar M, Ascagni M, Sugni M, Fascio U, Leggio L, Malinverno C, Scita G, Santucci S, Alava MJ, Zapperi S, La Porta CA.

Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):11408-11413. Epub 2016 Sep 28.

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