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Tubulins interact with porcine and human S proteins of the genus Alphacoronavirus and support successful assembly and release of infectious viral particles.

Rüdiger AT, Mayrhofer P, Ma-Lauer Y, Pohlentz G, Müthing J, von Brunn A, Schwegmann-Weßels C.

Virology. 2016 Oct;497:185-97. doi: 10.1016/j.virol.2016.07.022. Epub 2016 Jul 30.


Looking for a needle in a haystack: Cellular proteins that may interact with the tyrosine-based sorting signal of the TGEV S protein.

Trincone A, Schwegmann-Weßels C.

Virus Res. 2015 Apr 16;202:3-11. doi: 10.1016/j.virusres.2014.11.029. Epub 2014 Dec 4. Review.


Palmitoylation of the Alphacoronavirus TGEV spike protein S is essential for incorporation into virus-like particles but dispensable for S-M interaction.

Gelhaus S, Thaa B, Eschke K, Veit M, Schwegmann-Weßels C.

Virology. 2014 Sep;464-465:397-405. doi: 10.1016/j.virol.2014.07.035. Epub 2014 Aug 9.


Infection of differentiated airway epithelial cells from caprine lungs by viruses of the bovine respiratory disease complex.

Kirchhoff J, Uhlenbruck S, Keil GM, Schwegmann-Wessels C, Ganter M, Herrler G.

Vet Microbiol. 2014 May 14;170(1-2):58-64. doi: 10.1016/j.vetmic.2014.01.038. Epub 2014 Feb 9.


A lysine-methionine exchange in a coronavirus surface protein transforms a retention motif into an endocytosis signal.

Paul A, Trincone A, Siewert S, Herrler G, Schwegmann-Weßels C.

Biol Chem. 2014 Jun;395(6):657-65. doi: 10.1515/hsz-2013-0282.


Characterization of the sialic acid binding activity of influenza A viruses using soluble variants of the H7 and H9 hemagglutinins.

Sauer AK, Liang CH, Stech J, Peeters B, Quéré P, Schwegmann-Wessels C, Wu CY, Wong CH, Herrler G.

PLoS One. 2014 Feb 21;9(2):e89529. doi: 10.1371/journal.pone.0089529. eCollection 2014.


Replication characteristics of swine influenza viruses in precision-cut lung slices reflect the virulence properties of the viruses.

Meng F, Punyadarsaniya D, Uhlenbruck S, Hennig-Pauka I, Schwegmann-Wessels C, Ren X, Dürrwald R, Herrler G.

Vet Res. 2013 Nov 13;44:110. doi: 10.1186/1297-9716-44-110.


Differential sensitivity of bat cells to infection by enveloped RNA viruses: coronaviruses, paramyxoviruses, filoviruses, and influenza viruses.

Hoffmann M, Müller MA, Drexler JF, Glende J, Erdt M, Gützkow T, Losemann C, Binger T, Deng H, Schwegmann-Weßels C, Esser KH, Drosten C, Herrler G.

PLoS One. 2013 Aug 30;8(8):e72942. doi: 10.1371/journal.pone.0072942. eCollection 2013.


Evaluation on the efficacy and immunogenicity of recombinant DNA plasmids expressing spike genes from porcine transmissible gastroenteritis virus and porcine epidemic diarrhea virus.

Meng F, Ren Y, Suo S, Sun X, Li X, Li P, Yang W, Li G, Li L, Schwegmann-Wessels C, Herrler G, Ren X.

PLoS One. 2013;8(3):e57468. doi: 10.1371/journal.pone.0057468. Epub 2013 Mar 19.


Infection of differentiated porcine airway epithelial cells by influenza virus: differential susceptibility to infection by porcine and avian viruses.

Punyadarsaniya D, Liang CH, Winter C, Petersen H, Rautenschlein S, Hennig-Pauka I, Schwegmann-Wessels C, Wu CY, Wong CH, Herrler G.

PLoS One. 2011;6(12):e28429. doi: 10.1371/journal.pone.0028429. Epub 2011 Dec 9.


The SARS-coronavirus-host interactome: identification of cyclophilins as target for pan-coronavirus inhibitors.

Pfefferle S, Schöpf J, Kögl M, Friedel CC, Müller MA, Carbajo-Lozoya J, Stellberger T, von Dall'Armi E, Herzog P, Kallies S, Niemeyer D, Ditt V, Kuri T, Züst R, Pumpor K, Hilgenfeld R, Schwarz F, Zimmer R, Steffen I, Weber F, Thiel V, Herrler G, Thiel HJ, Schwegmann-Wessels C, Pöhlmann S, Haas J, Drosten C, von Brunn A.

PLoS Pathog. 2011 Oct;7(10):e1002331. doi: 10.1371/journal.ppat.1002331. Epub 2011 Oct 27.


The sialic acid binding activity of the S protein facilitates infection by porcine transmissible gastroenteritis coronavirus.

Schwegmann-Wessels C, Bauer S, Winter C, Enjuanes L, Laude H, Herrler G.

Virol J. 2011 Sep 12;8:435. doi: 10.1186/1743-422X-8-435.


Cholesterol is important for a post-adsorption step in the entry process of transmissible gastroenteritis virus.

Yin J, Glende J, Schwegmann-Wessels C, Enjuanes L, Herrler G, Ren X.

Antiviral Res. 2010 Dec;88(3):311-6. doi: 10.1016/j.antiviral.2010.10.002. Epub 2010 Oct 14.


Comparison of vesicular stomatitis virus pseudotyped with the S proteins from a porcine and a human coronavirus.

Schwegmann-Wessels C, Glende J, Ren X, Qu X, Deng H, Enjuanes L, Herrler G.

J Gen Virol. 2009 Jul;90(Pt 7):1724-9. doi: 10.1099/vir.0.009704-0. Epub 2009 Mar 4.


Identification of sugar residues involved in the binding of TGEV to porcine brush border membranes.

Schwegmann-Wessels C, Herrler G.

Methods Mol Biol. 2008;454:319-29. doi: 10.1007/978-1-59745-181-9_22.


Differential sensitivity of differentiated epithelial cells to respiratory viruses reveals different viral strategies of host infection.

Goris K, Uhlenbruck S, Schwegmann-Wessels C, Köhl W, Niedorf F, Stern M, Hewicker-Trautwein M, Bals R, Taylor G, Braun A, Bicker G, Kietzmann M, Herrler G.

J Virol. 2009 Feb;83(4):1962-8. doi: 10.1128/JVI.01271-08. Epub 2008 Dec 3.


Importance of cholesterol-rich membrane microdomains in the interaction of the S protein of SARS-coronavirus with the cellular receptor angiotensin-converting enzyme 2.

Glende J, Schwegmann-Wessels C, Al-Falah M, Pfefferle S, Qu X, Deng H, Drosten C, Naim HY, Herrler G.

Virology. 2008 Nov 25;381(2):215-21. doi: 10.1016/j.virol.2008.08.026. Epub 2008 Sep 23.


Importance of cholesterol for infection of cells by transmissible gastroenteritis virus.

Ren X, Glende J, Yin J, Schwegmann-Wessels C, Herrler G.

Virus Res. 2008 Nov;137(2):220-4. doi: 10.1016/j.virusres.2008.07.023. Epub 2008 Sep 16.


The spike protein of infectious bronchitis virus is retained intracellularly by a tyrosine motif.

Winter C, Schwegmann-Wessels C, Neumann U, Herrler G.

J Virol. 2008 Mar;82(6):2765-71. Epub 2007 Dec 19.


Intracellular transport of the S proteins of coronaviruses.

Schwegmann-Wessels C, Ren X, Herrler G.

Adv Exp Med Biol. 2006;581:271-5. No abstract available.

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