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Items: 1 to 20 of 299

1.

Identification of primary and secondary metabolites and transcriptome profile of soybean tissues during different stages of hypoxia.

Coutinho ID, Henning LMM, Döpp SA, Nepomuceno A, Moraes LAC, Marcolino-Gomes J, Richter C, Schwalbe H, Colnago LA.

Data Brief. 2018 Oct 15;21:1089-1100. doi: 10.1016/j.dib.2018.09.122. eCollection 2018 Dec.

2.

Combined smFRET and NMR analysis of riboswitch structural dynamics.

Bains JK, Blechar J, de Jesus V, Meiser N, Zetzsche H, Fürtig B, Schwalbe H, Hengesbach M.

Methods. 2019 Jan 15;153:22-34. doi: 10.1016/j.ymeth.2018.10.004. Epub 2018 Oct 12. No abstract available.

PMID:
30316819
3.

A New Photocaged Puromycin for an Efficient Labeling of Newly Translated Proteins in Living Neurons.

Elamri I, Heumüller M, Herzig LM, Stirnal E, Wachtveitl J, Schuman EM, Schwalbe H.

Chembiochem. 2018 Dec 4;19(23):2458-2464. doi: 10.1002/cbic.201800408. Epub 2018 Nov 8.

PMID:
30311996
4.

Optimal Destabilization of DNA Double Strands by Single-Nucleobase Caging.

Seyfried P, Heinz M, Pintér G, Klötzner DP, Becker Y, Bolte M, Jonker HRA, Stelzl LS, Hummer G, Schwalbe H, Heckel A.

Chemistry. 2018 Nov 27;24(66):17568-17576. doi: 10.1002/chem.201804040. Epub 2018 Nov 5.

PMID:
30199112
5.

Conformational switch in the ribosomal protein S1 guides unfolding of structured RNAs for translation initiation.

Qureshi NS, Bains JK, Sreeramulu S, Schwalbe H, Fürtig B.

Nucleic Acids Res. 2018 Nov 16;46(20):10917-10929. doi: 10.1093/nar/gky746.

6.

Investigations on the mode of action of gephyronic acid, an inhibitor of eukaryotic protein translation from myxobacteria.

Muthukumar Y, Münkemer J, Mathieu D, Richter C, Schwalbe H, Steinmetz H, Kessler W, Reichelt J, Beutling U, Frank R, Büssow K, van den Heuvel J, Brönstrup M, Taylor RE, Laschat S, Sasse F.

PLoS One. 2018 Jul 31;13(7):e0201605. doi: 10.1371/journal.pone.0201605. eCollection 2018.

7.

On the Implication of Water on Fragment-to-Ligand Growth in Kinase Binding Thermodynamics.

Wienen-Schmidt B, Wulsdorf T, Jonker HRA, Saxena K, Kudlinzki D, Linhard V, Sreeramulu S, Heine A, Schwalbe H, Klebe G.

ChemMedChem. 2018 Sep 19;13(18):1988-1996. doi: 10.1002/cmdc.201800438. Epub 2018 Aug 23.

PMID:
30058283
8.

Chemo-Enzymatic Synthesis of Position-Specifically Modified RNA for Biophysical Studies including Light Control and NMR Spectroscopy.

Keyhani S, Goldau T, Blümler A, Heckel A, Schwalbe H.

Angew Chem Int Ed Engl. 2018 Sep 10;57(37):12017-12021. doi: 10.1002/anie.201807125. Epub 2018 Aug 10.

PMID:
30007102
9.

NVP-BHG712: Effects of Regioisomers on the Affinity and Selectivity toward the EPHrin Family.

Tröster A, Heinzlmeir S, Berger BT, Gande SL, Saxena K, Sreeramulu S, Linhard V, Nasiri AH, Bolte M, Müller S, Kuster B, Médard G, Kudlinzki D, Schwalbe H.

ChemMedChem. 2018 Aug 20;13(16):1629-1633. doi: 10.1002/cmdc.201800398. Epub 2018 Jul 20.

PMID:
29928781
10.

Modulation of the Allosteric Communication between the Polo-Box Domain and the Catalytic Domain in Plk1 by Small Compounds.

Raab M, Sanhaji M, Pietsch L, Béquignon I, Herbrand AK, Süß E, Gande SL, Caspar B, Kudlinzki D, Saxena K, Sreeramulu S, Schwalbe H, Strebhardt K, Biondi RM.

ACS Chem Biol. 2018 Aug 17;13(8):1921-1931. doi: 10.1021/acschembio.7b01078. Epub 2018 Jun 28.

PMID:
29927572
11.

Paradoxically, Most Flexible Ligand Binds Most Entropy-Favored: Intriguing Impact of Ligand Flexibility and Solvation on Drug-Kinase Binding.

Wienen-Schmidt B, Jonker HRA, Wulsdorf T, Gerber HD, Saxena K, Kudlinzki D, Sreeramulu S, Parigi G, Luchinat C, Heine A, Schwalbe H, Klebe G.

J Med Chem. 2018 Jul 3. doi: 10.1021/acs.jmedchem.8b00105. [Epub ahead of print]

PMID:
29909615
12.

The domain architecture of PtkA, the first tyrosine kinase from Mycobacterium tuberculosis, differs from the conventional kinase architecture.

Niesteruk A, Jonker HRA, Richter C, Linhard V, Sreeramulu S, Schwalbe H.

J Biol Chem. 2018 Jul 27;293(30):11823-11836. doi: 10.1074/jbc.RA117.000120. Epub 2018 Jun 8.

PMID:
29884774
13.

Targeting RNA structure in SMN2 reverses spinal muscular atrophy molecular phenotypes.

Garcia-Lopez A, Tessaro F, Jonker HRA, Wacker A, Richter C, Comte A, Berntenis N, Schmucki R, Hatje K, Petermann O, Chiriano G, Perozzo R, Sciarra D, Konieczny P, Faustino I, Fournet G, Orozco M, Artero R, Metzger F, Ebeling M, Goekjian P, Joseph B, Schwalbe H, Scapozza L.

Nat Commun. 2018 May 23;9(1):2032. doi: 10.1038/s41467-018-04110-1.

14.

iNEXT: a European facility network to stimulate translational structural biology.

iNEXT Consortium.

FEBS Lett. 2018 Jun;592(12):1909-1917. doi: 10.1002/1873-3468.13062. Epub 2018 May 15. No abstract available.

PMID:
29766495
15.

Cell penetrating thiazole peptides inhibit c-MYC expression via site-specific targeting of c-MYC G-quadruplex.

Dutta D, Debnath M, Müller D, Paul R, Das T, Bessi I, Schwalbe H, Dash J.

Nucleic Acids Res. 2018 Jun 20;46(11):5355-5365. doi: 10.1093/nar/gky385.

16.

Improved high-yield expression, purification and refolding of recombinant mammalian prion proteins under aerosol-free elevated biological safety conditions.

Rehbein P, Schwalbe H.

Protein Expr Purif. 2018 Oct;150:53-60. doi: 10.1016/j.pep.2018.04.018. Epub 2018 May 8.

PMID:
29751084
17.

Structural Characterization of the Interaction of the Fibroblast Growth Factor Receptor with a Small Molecule Allosteric Inhibitor.

Kappert F, Sreeramulu S, Jonker HRA, Richter C, Rogov VV, Proschak E, Hargittay B, Saxena K, Schwalbe H.

Chemistry. 2018 Jun 4;24(31):7861-7865. doi: 10.1002/chem.201801770. Epub 2018 May 3.

PMID:
29656465
18.

Life times of metastable states guide regulatory signaling in transcriptional riboswitches.

Helmling C, Klötzner DP, Sochor F, Mooney RA, Wacker A, Landick R, Fürtig B, Heckel A, Schwalbe H.

Nat Commun. 2018 Mar 5;9(1):944. doi: 10.1038/s41467-018-03375-w.

19.

Structural characterization of the intrinsically disordered domain of Mycobacterium tuberculosis protein tyrosine kinase A.

Niesteruk A, Hutchison M, Sreeramulu S, Jonker HRA, Richter C, Abele R, Bock C, Schwalbe H.

FEBS Lett. 2018 Apr;592(7):1233-1245. doi: 10.1002/1873-3468.13022. Epub 2018 Mar 25.

PMID:
29494752
20.

Georatusin, a Specific Antiparasitic Polyketide-Peptide Hybrid from the Fungus Geomyces auratus.

Shi YM, Richter C, Challinor VL, Grün P, Girela Del Rio A, Kaiser M, Schüffler A, Piepenbring M, Schwalbe H, Bode HB.

Org Lett. 2018 Mar 16;20(6):1563-1567. doi: 10.1021/acs.orglett.8b00293. Epub 2018 Feb 23.

PMID:
29474084

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