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Items: 1 to 20 of 662

1.

Structural and stereoelectronic insights into oxygenase-catalyzed formation of ethylene from 2-oxoglutarate.

Zhang Z, Smart TJ, Choi H, Hardy F, Lohans CT, Abboud MI, Richardson MSW, Paton RS, McDonough MA, Schofield CJ.

Proc Natl Acad Sci U S A. 2017 Apr 18. pii: 201617760. doi: 10.1073/pnas.1617760114. [Epub ahead of print]

PMID:
28420789
2.

Improving perceptions of cognitive-behavioral therapy with brief website exposure: Does neuroscientific allure impact attitudes?

Schofield CA, Weis H, Ponzini G, McHugh RK.

J Behav Ther Exp Psychiatry. 2017 Mar 31;57:53-61. doi: 10.1016/j.jbtep.2017.03.003. [Epub ahead of print]

PMID:
28395237
3.

Highly selective inhibition of histone demethylases by de novo macrocyclic peptides.

Kawamura A, Münzel M, Kojima T, Yapp C, Bhushan B, Goto Y, Tumber A, Katoh T, King ON, Passioura T, Walport LJ, Hatch SB, Madden S, Müller S, Brennan PE, Chowdhury R, Hopkinson RJ, Suga H, Schofield CJ.

Nat Commun. 2017 Apr 6;8:14773. doi: 10.1038/ncomms14773.

4.

Assessing histone demethylase inhibitors in cells: lessons learned.

Hatch SB, Yapp C, Montenegro RC, Savitsky P, Gamble V, Tumber A, Ruda GF, Bavetsias V, Fedorov O, Atrash B, Raynaud F, Lanigan R, Carmichael L, Tomlin K, Burke R, Westaway SM, Brown JA, Prinjha RK, Martinez ED, Oppermann U, Schofield CJ, Bountra C, Kawamura A, Blagg J, Brennan PE, Rossanese O, Müller S.

Epigenetics Chromatin. 2017 Mar 1;10:9. doi: 10.1186/s13072-017-0116-6. eCollection 2017.

5.

Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells.

Tumber A, Nuzzi A, Hookway ES, Hatch SB, Velupillai S, Johansson C, Kawamura A, Savitsky P, Yapp C, Szykowska A, Wu N, Bountra C, Strain-Damerell C, Burgess-Brown NA, Ruda GF, Fedorov O, Munro S, England KS, Nowak RP, Schofield CJ, La Thangue NB, Pawlyn C, Davies F, Morgan G, Athanasou N, Müller S, Oppermann U, Brennan PE.

Cell Chem Biol. 2017 Mar 16;24(3):371-380. doi: 10.1016/j.chembiol.2017.02.006. Epub 2017 Mar 2.

6.

19 F-NMR Reveals the Role of Mobile Loops in Product and Inhibitor Binding by the São Paulo Metallo-β-Lactamase.

Abboud MI, Hinchliffe P, Brem J, Macsics R, Pfeffer I, Makena A, Umland KD, Rydzik AM, Li GB, Spencer J, Claridge TD, Schofield CJ.

Angew Chem Int Ed Engl. 2017 Mar 27;56(14):3862-3866. doi: 10.1002/anie.201612185. Epub 2017 Mar 2.

PMID:
28252254
7.

KDM3A coordinates actin dynamics with intraflagellar transport to regulate cilia stability.

Yeyati PL, Schiller R, Mali G, Kasioulis I, Kawamura A, Adams IR, Playfoot C, Gilbert N, van Heyningen V, Wills J, von Kriegsheim A, Finch A, Sakai J, Schofield CJ, Jackson IJ, Mill P.

J Cell Biol. 2017 Apr 3;216(4):999-1013. doi: 10.1083/jcb.201607032. Epub 2017 Feb 28.

8.

Cyclic Boronates Inhibit All Classes of β-Lactamases.

Cahill ST, Cain R, Wang DY, Lohans CT, Wareham DW, Oswin HP, Mohammed J, Spencer J, Fishwick CW, McDonough MA, Schofield CJ, Brem J.

Antimicrob Agents Chemother. 2017 Mar 24;61(4). pii: e02260-16. doi: 10.1128/AAC.02260-16. Print 2017 Apr.

9.

Insights into the Mechanistic Basis of Plasmid-Mediated Colistin Resistance from Crystal Structures of the Catalytic Domain of MCR-1.

Hinchliffe P, Yang QE, Portal E, Young T, Li H, Tooke CL, Carvalho MJ, Paterson NG, Brem J, Niumsup PR, Tansawai U, Lei L, Li M, Shen Z, Wang Y, Schofield CJ, Mulholland AJ, Shen J, Fey N, Walsh TR, Spencer J.

Sci Rep. 2017 Jan 6;7:39392. doi: 10.1038/srep39392.

10.

Human carnitine biosynthesis proceeds via (2S,3S)-3-hydroxy-Nε-trimethyllysine.

Leśniak RK, Markolovic S, Tars K, Schofield CJ.

Chem Commun (Camb). 2016 Dec 22;53(2):440-442. doi: 10.1039/c6cc08381a.

PMID:
27965989
11.

Rituximab-Associated Inflammatory Progressive Multifocal Leukoencephalopathy.

Punch C, Schofield C, Harris P.

Case Rep Infect Dis. 2016;2016:8915047. Epub 2016 Nov 14.

12.

Use of ferrous iron by metallo-β-lactamases.

Cahill ST, Tarhonskaya H, Rydzik AM, Flashman E, McDonough MA, Schofield CJ, Brem J.

J Inorg Biochem. 2016 Oct;163:185-193. doi: 10.1016/j.jinorgbio.2016.07.013. Epub 2016 Jul 26.

13.

Expression of Idh1R132H in the Murine Subventricular Zone Stem Cell Niche Recapitulates Features of Early Gliomagenesis.

Bardella C, Al-Dalahmah O, Krell D, Brazauskas P, Al-Qahtani K, Tomkova M, Adam J, Serres S, Lockstone H, Freeman-Mills L, Pfeffer I, Sibson N, Goldin R, Schuster-Böeckler B, Pollard PJ, Soga T, McCullagh JS, Schofield CJ, Mulholland P, Ansorge O, Kriaucionis S, Ratcliffe PJ, Szele FG, Tomlinson I.

Cancer Cell. 2016 Oct 10;30(4):578-594. doi: 10.1016/j.ccell.2016.08.017. Epub 2016 Sep 29.

14.

Bisthiazolidines: A Substrate-Mimicking Scaffold as an Inhibitor of the NDM-1 Carbapenemase.

González MM, Kosmopoulou M, Mojica MF, Castillo V, Hinchliffe P, Pettinati I, Brem J, Schofield CJ, Mahler G, Bonomo RA, Llarrull LI, Spencer J, Vila AJ.

ACS Infect Dis. 2015 Nov 13;1(11):544-54. doi: 10.1021/acsinfecdis.5b00046. Epub 2015 Jul 20.

15.

Characterization of IL-17AA and IL-17FF in rheumatoid arthritis and multiple sclerosis.

Schofield C, Fischer SK, Townsend MJ, Mosesova S, Peng K, Setiadi AF, Song A, Baruch A.

Bioanalysis. 2016 Nov;8(22):2317-2327. Epub 2016 Sep 13.

16.

Adaptation of a paradigm for examining the development of fear beliefs through the verbal information pathway in preschool-age children.

Rifkin LS, Schofield CA, Beard C, Armstrong T.

Behav Res Ther. 2016 Dec;87:34-39. doi: 10.1016/j.brat.2016.08.013. Epub 2016 Aug 18.

PMID:
27588374
17.

Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases.

Chowdhury R, Leung IK, Tian YM, Abboud MI, Ge W, Domene C, Cantrelle FX, Landrieu I, Hardy AP, Pugh CW, Ratcliffe PJ, Claridge TD, Schofield CJ.

Nat Commun. 2016 Aug 26;7:12673. doi: 10.1038/ncomms12673.

18.

Improved localisation for 2-hydroxyglutarate detection at 3T using long-TE semi-LASER.

Berrington A, Voets NL, Plaha P, Larkin SJ, Mccullagh J, Stacey R, Yildirim M, Schofield CJ, Jezzard P, Cadoux-Hudson T, Ansorge O, Emir UE.

Tomography. 2016 Jun;2(2):94-105.

19.

Detection of mSiglec-E, in solution and expressed on the surface of Chinese hamster ovary cells, using sialic acid functionalised gold nanoparticles.

Schofield CL, Marín MJ, Rejzek M, Crocker PR, Field RA, Russell DA.

Analyst. 2016 Oct 21;141(20):5799-5809. Epub 2016 Aug 18.

PMID:
27537280
20.

Normal tissue radioprotection by amifostine via Warburg-type effects.

Koukourakis MI, Giatromanolaki A, Zois CE, Kalamida D, Pouliliou S, Karagounis IV, Yeh TL, Abboud MI, Claridge TD, Schofield CJ, Sivridis E, Simopoulos C, Tokmakidis SP, Harris AL.

Sci Rep. 2016 Aug 10;6:30986. doi: 10.1038/srep30986.

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