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Items: 1 to 20 of 505

1.

Template-assisted synthesis of adenine-mutagenized cDNA by a retroelement protein complex.

Handa S, Jiang Y, Tao S, Foreman R, Schinazi RF, Miller JF, Ghosh P.

Nucleic Acids Res. 2018 Jul 11. doi: 10.1093/nar/gky620. [Epub ahead of print]

PMID:
30007279
2.

SIV persistence in cellular and anatomic reservoirs in ART-suppressed infant rhesus macaques.

Mavigner M, Habib J, Deleage C, Rosen E, Mattingly C, Bricker K, Kashuba A, Amblard F, Schinazi RF, Jean S, Cohen J, McGary C, Paiardini M, Wood MP, Sodora DL, Silvestri G, Estes J, Chahroudi A.

J Virol. 2018 Jul 11. pii: JVI.00562-18. doi: 10.1128/JVI.00562-18. [Epub ahead of print]

PMID:
29997216
3.

Synthesis and antiviral evaluation of novel peptidomimetics as norovirus protease inhibitors.

Amblard F, Zhou S, Liu P, Yoon J, Cox B, Muzzarelli K, Kuiper BD, Kovari LC, Schinazi RF.

Bioorg Med Chem Lett. 2018 Jul 1;28(12):2165-2170. doi: 10.1016/j.bmcl.2018.05.012. Epub 2018 May 8.

PMID:
29779977
4.

Expression, purification, and characterization of a GII.4 norovirus protease.

Kuiper BD, Keusch BJ, Holcomb J, Muzzarelli KM, Amblard F, Liu P, Zhou S, Kovari IA, Yang Z, Schinazi RF, Kovari LC.

Infect Disord Drug Targets. 2018 May 20. doi: 10.2174/1871526518666180521091158. [Epub ahead of print]

PMID:
29779487
5.

HIV transmission in discordant couples in Africa in the context of antiretroviral therapy availability.

Woodson E, Goldberg A, Michelo C, Basu D, Tao S, Schinazi R, Jiang Y, Kilembe W, Karita E, Allen S, Hunter E.

AIDS. 2018 Jul 31;32(12):1613-1623. doi: 10.1097/QAD.0000000000001871.

PMID:
29762171
6.

Treatment of hepatitis C virus infection with direct-acting antiviral agents: 100% cure?

Asselah T, Marcellin P, Schinazi RF.

Liver Int. 2018 Feb;38 Suppl 1:7-13. doi: 10.1111/liv.13673. Review.

PMID:
29427484
7.

Towards HBV curative therapies.

Schinazi RF, Ehteshami M, Bassit L, Asselah T.

Liver Int. 2018 Feb;38 Suppl 1:102-114. doi: 10.1111/liv.13656. Review.

PMID:
29427479
8.

Mobile Health Intervention to Reduce HIV Transmission: A Randomized Trial of Behaviorally Enhanced HIV Treatment as Prevention (B-TasP).

Kalichman SC, Cherry C, Kalichman MO, Eaton LA, Kohler JJ, Montero C, Schinazi RF.

J Acquir Immune Defic Syndr. 2018 May 1;78(1):34-42. doi: 10.1097/QAI.0000000000001637.

PMID:
29406429
9.

Novel mechanisms to inhibit HIV reservoir seeding using Jak inhibitors.

Gavegnano C, Brehm JH, Dupuy FP, Talla A, Ribeiro SP, Kulpa DA, Cameron C, Santos S, Hurwitz SJ, Marconi VC, Routy JP, Sabbagh L, Schinazi RF, Sékaly RP.

PLoS Pathog. 2017 Dec 21;13(12):e1006740. doi: 10.1371/journal.ppat.1006740. eCollection 2017 Dec.

10.

Research priorities for the discovery of a cure for chronic hepatitis B: Report of a workshop.

Block TM, Alter H, Brown N, Brownstein A, Brosgart C, Chang KM, Chen PJ, Cohen C, El-Serag H, Feld J, Gish R, Glenn J, Greten TF, Guo JT, Hoshida Y, Kowdley KV, Li W, Lok AS, McMahon B, Mehta A, Perrillo R, Rice CM, Rinaudo J, Schinazi RF, Shetty K.

Antiviral Res. 2018 Feb;150:93-100. doi: 10.1016/j.antiviral.2017.12.006. Epub 2017 Dec 14.

11.

Ruxolitinib sensitizes ovarian cancer to reduced dose Taxol, limits tumor growth and improves survival in immune competent mice.

Reeves PM, Abbaslou MA, Kools FRW, Vutipongsatorn K, Tong X, Gavegano C, Schinazi RF, Poznansky MC.

Oncotarget. 2017 Oct 4;8(55):94040-94053. doi: 10.18632/oncotarget.21541. eCollection 2017 Nov 7.

12.

Acute acalculous cholecystitis during zika virus infection in an immunocompromised patient.

Ono SK, Bassit L, Van Vaisberg V, Avancini Ferreira Alves V, Caldini EG, Herman BD, Shabman R, Fedorova NB, Paranaguá-Vezozzo D, Sampaio CT, Lages RB, Terrabuio D, Andraus W, Schinazi RF, Carrilho FJ.

Hepatology. 2018 May;67(5):2051-2054. doi: 10.1002/hep.29682. Epub 2018 Feb 27. No abstract available.

PMID:
29171859
13.

Synthesis of (2S)-2-Chloro-2-fluororibolactone via Stereoselective Electrophilic Fluorination.

De Schutter C, Sari O, Coats SJ, Amblard F, Schinazi RF.

J Org Chem. 2017 Dec 15;82(24):13171-13178. doi: 10.1021/acs.joc.7b02245. Epub 2017 Dec 4.

PMID:
29140703
14.

Synthesis and anti-HCV activity of a series of β-d-2'-deoxy-2'-dibromo nucleosides and their corresponding phosphoramidate prodrugs.

Chen Z, Cox BD, Garnier-Amblard EC, McBrayer TR, Coats SJ, Schinazi RF, Amblard F.

Bioorg Med Chem Lett. 2017 Dec 1;27(23):5296-5299. doi: 10.1016/j.bmcl.2017.10.024. Epub 2017 Oct 12.

PMID:
29066308
15.

Metabolism of Nucleosides and Nucleotides Prodrugs.

De Schutter C, Ehteshami M, Hammond ET, Amblard F, Schinazi RF.

Curr Pharm Des. 2017 Oct 11. doi: 10.2174/1381612823666171011104158. [Epub ahead of print]

PMID:
29022511
16.

A research agenda for curing chronic hepatitis B virus infection.

Alter H, Block T, Brown N, Brownstein A, Brosgart C, Chang KM, Chen PJ, Chisari FV, Cohen C, El-Serag H, Feld J, Gish R, Glenn J, Greten T, Guo H, Guo JT, Hoshida Y, Hu J, Kowdley KV, Li W, Liang J, Locarnini S, Lok AS, Mason W, McMahon B, Mehta A, Perrillo R, Revill P, Rice CM, Rinaudo J, Schinazi R, Seeger C, Shetty K, Tavis J, Zoulim F.

Hepatology. 2018 Mar;67(3):1127-1131. doi: 10.1002/hep.29509. Epub 2018 Jan 24. No abstract available.

17.

Jak Inhibitors Modulate Production of Replication-Competent Zika Virus in Human Hofbauer, Trophoblasts, and Neuroblastoma cells.

Gavegnano C, Bassit LC, Cox BD, Hsiao HM, Johnson EL, Suthar M, Chakraborty R, Schinazi RF.

Pathog Immun. 2017;2(2):199-218. doi: 10.20411/pai.v2i2.190. Epub 2017 May 24.

18.

Synthesis of sulfamoylbenzamide derivatives as HBV capsid assembly effector.

Sari O, Boucle S, Cox BD, Ozturk T, Russell OO, Bassit L, Amblard F, Schinazi RF.

Eur J Med Chem. 2017 Sep 29;138:407-421. doi: 10.1016/j.ejmech.2017.06.062. Epub 2017 Jun 29.

PMID:
28688280
19.

A CRISPR/Cas9 approach reveals that the polymerase activity of DNA polymerase β is dispensable for HIV-1 infection in dividing and nondividing cells.

Goetze RW, Kim DH, Schinazi RF, Kim B.

J Biol Chem. 2017 Aug 25;292(34):14016-14025. doi: 10.1074/jbc.M117.793661. Epub 2017 Jul 6.

20.

Zika in the Americas, year 2: What have we learned? What gaps remain? A report from the Global Virus Network.

Aliota MT, Bassit L, Bradrick SS, Cox B, Garcia-Blanco MA, Gavegnano C, Friedrich TC, Golos TG, Griffin DE, Haddow AD, Kallas EG, Kitron U, Lecuit M, Magnani DM, Marrs C, Mercer N, McSweegan E, Ng LFP, O'Connor DH, Osorio JE, Ribeiro GS, Ricciardi M, Rossi SL, Saade G, Schinazi RF, Schott-Lerner GO, Shan C, Shi PY, Watkins DI, Vasilakis N, Weaver SC.

Antiviral Res. 2017 Aug;144:223-246. doi: 10.1016/j.antiviral.2017.06.001. Epub 2017 Jun 6. Review.

PMID:
28595824

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