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Items: 1 to 20 of 55

1.

Evidence that the rate of strong selective sweeps increases with population size in the great apes.

Nam K, Munch K, Mailund T, Nater A, Greminger MP, Krützen M, Marquès-Bonet T, Schierup MH.

Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):1613-1618. doi: 10.1073/pnas.1605660114. Epub 2017 Jan 30.

2.

Spitting for Science: Danish High School Students Commit to a Large-Scale Self-Reported Genetic Study.

Athanasiadis G, Jørgensen FG, Cheng JY, Kjærgaard PC, Schierup MH, Mailund T.

PLoS One. 2016 Aug 29;11(8):e0161822. doi: 10.1371/journal.pone.0161822. eCollection 2016.

3.

High-resolution genetic maps of Lotus japonicus and L. burttii based on re-sequencing of recombinant inbred lines.

Shah N, Hirakawa H, Kusakabe S, Sandal N, Stougaard J, Schierup MH, Sato S, Andersen SU.

DNA Res. 2016 Jul 3. pii: dsw033. [Epub ahead of print]

4.

Demographic History of the Genus Pan Inferred from Whole Mitochondrial Genome Reconstructions.

Lobon I, Tucci S, de Manuel M, Ghirotto S, Benazzo A, Prado-Martinez J, Lorente-Galdos B, Nam K, Dabad M, Hernandez-Rodriguez J, Comas D, Navarro A, Schierup MH, Andres AM, Barbujani G, Hvilsom C, Marques-Bonet T.

Genome Biol Evol. 2016 Jul 3;8(6):2020-30. doi: 10.1093/gbe/evw124.

5.

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores.

Vilhjálmsson BJ, Yang J, Finucane HK, Gusev A, Lindström S, Ripke S, Genovese G, Loh PR, Bhatia G, Do R, Hayeck T, Won HH; Schizophrenia Working Group of the Psychiatric Genomics Consortium, Discovery, Biology, and Risk of Inherited Variants in Breast Cancer (DRIVE) study, Kathiresan S, Pato M, Pato C, Tamimi R, Stahl E, Zaitlen N, Pasaniuc B, Belbin G, Kenny EE, Schierup MH, De Jager P, Patsopoulos NA, McCarroll S, Daly M, Purcell S, Chasman D, Neale B, Goddard M, Visscher PM, Kraft P, Patterson N, Price AL.

Am J Hum Genet. 2015 Oct 1;97(4):576-92. doi: 10.1016/j.ajhg.2015.09.001.

6.

Strong Selective Sweeps on the X Chromosome in the Human-Chimpanzee Ancestor Explain Its Low Divergence.

Dutheil JY, Munch K, Nam K, Mailund T, Schierup MH.

PLoS Genet. 2015 Aug 14;11(8):e1005451. doi: 10.1371/journal.pgen.1005451. eCollection 2015 Aug.

7.

Extreme selective sweeps independently targeted the X chromosomes of the great apes.

Nam K, Munch K, Hobolth A, Dutheil JY, Veeramah KR, Woerner AE, Hammer MF; Great Ape Genome Diversity Project, Mailund T, Schierup MH.

Proc Natl Acad Sci U S A. 2015 May 19;112(20):6413-8. doi: 10.1073/pnas.1419306112. Epub 2015 May 4.

8.

Inference of purifying and positive selection in three subspecies of chimpanzees (Pan troglodytes) from exome sequencing.

Bataillon T, Duan J, Hvilsom C, Jin X, Li Y, Skov L, Glemin S, Munch K, Jiang T, Qian Y, Hobolth A, Wang J, Mailund T, Siegismund HR, Schierup MH.

Genome Biol Evol. 2015 Mar 30;7(4):1122-32. doi: 10.1093/gbe/evv058.

9.

Novel variation and de novo mutation rates in population-wide de novo assembled Danish trios.

Besenbacher S, Liu S, Izarzugaza JM, Grove J, Belling K, Bork-Jensen J, Huang S, Als TD, Li S, Yadav R, Rubio-García A, Lescai F, Demontis D, Rao J, Ye W, Mailund T, Friborg RM, Pedersen CN, Xu R, Sun J, Liu H, Wang O, Cheng X, Flores D, Rydza E, Rapacki K, Damm Sørensen J, Chmura P, Westergaard D, Dworzynski P, Sørensen TI, Lund O, Hansen T, Xu X, Li N, Bolund L, Pedersen O, Eiberg H, Krogh A, Børglum AD, Brunak S, Kristiansen K, Schierup MH, Wang J, Gupta R, Villesen P, Rasmussen S.

Nat Commun. 2015 Jan 19;6:5969. doi: 10.1038/ncomms6969.

10.

Unraveling recombination rate evolution using ancestral recombination maps.

Munch K, Schierup MH, Mailund T.

Bioessays. 2014 Sep;36(9):892-900. doi: 10.1002/bies.201400047. Epub 2014 Jul 14. Review.

11.

Spider genomes provide insight into composition and evolution of venom and silk.

Sanggaard KW, Bechsgaard JS, Fang X, Duan J, Dyrlund TF, Gupta V, Jiang X, Cheng L, Fan D, Feng Y, Han L, Huang Z, Wu Z, Liao L, Settepani V, Thøgersen IB, Vanthournout B, Wang T, Zhu Y, Funch P, Enghild JJ, Schauser L, Andersen SU, Villesen P, Schierup MH, Bilde T, Wang J.

Nat Commun. 2014 May 6;5:3765. doi: 10.1038/ncomms4765. Erratum in: Nat Commun. 2014;5:4590.

12.

Identifying disease associated genes by network propagation.

Qian Y, Besenbacher S, Mailund T, Schierup MH.

BMC Syst Biol. 2014;8 Suppl 1:S6. doi: 10.1186/1752-0509-8-S1-S6. Epub 2014 Jan 24.

13.

Variation and association to diabetes in 2000 full mtDNA sequences mined from an exome study in a Danish population.

Li S, Besenbacher S, Li Y, Kristiansen K, Grarup N, Albrechtsen A, Sparsø T, Korneliussen T, Hansen T, Wang J, Nielsen R, Pedersen O, Bolund L, Schierup MH.

Eur J Hum Genet. 2014 Aug;22(8):1040-5. doi: 10.1038/ejhg.2013.282. Epub 2014 Jan 22.

14.

A fine-scale recombination map of the human-chimpanzee ancestor reveals faster change in humans than in chimpanzees and a strong impact of GC-biased gene conversion.

Munch K, Mailund T, Dutheil JY, Schierup MH.

Genome Res. 2014 Mar;24(3):467-74. doi: 10.1101/gr.158469.113. Epub 2013 Nov 4.

15.

Great ape genetic diversity and population history.

Prado-Martinez J, Sudmant PH, Kidd JM, Li H, Kelley JL, Lorente-Galdos B, Veeramah KR, Woerner AE, O'Connor TD, Santpere G, Cagan A, Theunert C, Casals F, Laayouni H, Munch K, Hobolth A, Halager AE, Malig M, Hernandez-Rodriguez J, Hernando-Herraez I, Prüfer K, Pybus M, Johnstone L, Lachmann M, Alkan C, Twigg D, Petit N, Baker C, Hormozdiari F, Fernandez-Callejo M, Dabad M, Wilson ML, Stevison L, Camprubí C, Carvalho T, Ruiz-Herrera A, Vives L, Mele M, Abello T, Kondova I, Bontrop RE, Pusey A, Lankester F, Kiyang JA, Bergl RA, Lonsdorf E, Myers S, Ventura M, Gagneux P, Comas D, Siegismund H, Blanc J, Agueda-Calpena L, Gut M, Fulton L, Tishkoff SA, Mullikin JC, Wilson RK, Gut IG, Gonder MK, Ryder OA, Hahn BH, Navarro A, Akey JM, Bertranpetit J, Reich D, Mailund T, Schierup MH, Hvilsom C, Andrés AM, Wall JD, Bustamante CD, Hammer MF, Eichler EE, Marques-Bonet T.

Nature. 2013 Jul 25;499(7459):471-5. doi: 10.1038/nature12228. Epub 2013 Jul 3.

16.

DNA Topoisomerases maintain promoters in a state competent for transcriptional activation in Saccharomyces cerevisiae.

Pedersen JM, Fredsoe J, Roedgaard M, Andreasen L, Mundbjerg K, Kruhøffer M, Brinch M, Schierup MH, Bjergbaek L, Andersen AH.

PLoS Genet. 2012;8(12):e1003128. doi: 10.1371/journal.pgen.1003128. Epub 2012 Dec 20.

17.

A new isolation with migration model along complete genomes infers very different divergence processes among closely related great ape species.

Mailund T, Halager AE, Westergaard M, Dutheil JY, Munch K, Andersen LN, Lunter G, Prüfer K, Scally A, Hobolth A, Schierup MH.

PLoS Genet. 2012;8(12):e1003125. doi: 10.1371/journal.pgen.1003125. Epub 2012 Dec 20.

18.

SOAPindel: efficient identification of indels from short paired reads.

Li S, Li R, Li H, Lu J, Li Y, Bolund L, Schierup MH, Wang J.

Genome Res. 2013 Jan;23(1):195-200. doi: 10.1101/gr.132480.111. Epub 2012 Sep 12.

19.

An effort to use human-based exome capture methods to analyze chimpanzee and macaque exomes.

Jin X, He M, Ferguson B, Meng Y, Ouyang L, Ren J, Mailund T, Sun F, Sun L, Shen J, Zhuo M, Song L, Wang J, Ling F, Zhu Y, Hvilsom C, Siegismund H, Liu X, Gong Z, Ji F, Wang X, Liu B, Zhang Y, Hou J, Wang J, Zhao H, Wang Y, Fang X, Zhang G, Wang J, Zhang X, Schierup MH, Du H, Wang J, Wang X.

PLoS One. 2012;7(7):e40637. doi: 10.1371/journal.pone.0040637. Epub 2012 Jul 27.

20.

The bonobo genome compared with the chimpanzee and human genomes.

Prüfer K, Munch K, Hellmann I, Akagi K, Miller JR, Walenz B, Koren S, Sutton G, Kodira C, Winer R, Knight JR, Mullikin JC, Meader SJ, Ponting CP, Lunter G, Higashino S, Hobolth A, Dutheil J, Karakoç E, Alkan C, Sajjadian S, Catacchio CR, Ventura M, Marques-Bonet T, Eichler EE, André C, Atencia R, Mugisha L, Junhold J, Patterson N, Siebauer M, Good JM, Fischer A, Ptak SE, Lachmann M, Symer DE, Mailund T, Schierup MH, Andrés AM, Kelso J, Pääbo S.

Nature. 2012 Jun 28;486(7404):527-31. doi: 10.1038/nature11128.

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