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Laser capture microdissection enables transcriptomic analysis of dividing and quiescent liver stages of Plasmodium relapsing species.

Cubi R, Vembar SS, Biton A, Franetich JF, Bordessoulles M, Sossau D, Zanghi G, Bosson-Vanga H, Benard M, Moreno A, Dereuddre-Bosquet N, Le Grand R, Scherf A, Mazier D.

Cell Microbiol. 2017 Mar 3. doi: 10.1111/cmi.12735. [Epub ahead of print]


Trans-acting GC-rich non-coding RNA at var expression site modulates gene counting in malaria parasite.

Guizetti J, Barcons-Simon A, Scherf A.

Nucleic Acids Res. 2016 Nov 16;44(20):9710-9718. Epub 2016 Jul 27.


Complete telomere-to-telomere de novo assembly of the Plasmodium falciparum genome through long-read (>11 kb), single molecule, real-time sequencing.

Vembar SS, Seetin M, Lambert C, Nattestad M, Schatz MC, Baybayan P, Scherf A, Smith ML.

DNA Res. 2016 Aug;23(4):339-51. doi: 10.1093/dnares/dsw022. Epub 2016 Jun 26.


Translational regulation in blood stages of the malaria parasite Plasmodium spp.: systems-wide studies pave the way.

Vembar SS, Droll D, Scherf A.

Wiley Interdiscip Rev RNA. 2016 Nov;7(6):772-792. doi: 10.1002/wrna.1365. Epub 2016 May 26. Review.


Orientation relationship of eutectoid FeAl and FeAl2.

Scherf A, Kauffmann A, Kauffmann-Weiss S, Scherer T, Li X, Stein F, Heilmaier M.

J Appl Crystallogr. 2016 Feb 24;49(Pt 2):442-449. eCollection 2016 Apr 1.


Plasmodium falciparum PfSET7: enzymatic characterization and cellular localization of a novel protein methyltransferase in sporozoite, liver and erythrocytic stage parasites.

Chen PB, Ding S, Zanghì G, Soulard V, DiMaggio PA, Fuchter MJ, Mecheri S, Mazier D, Scherf A, Malmquist NA.

Sci Rep. 2016 Feb 23;6:21802. doi: 10.1038/srep21802.


The PfAlba1 RNA-binding protein is an important regulator of translational timing in Plasmodium falciparum blood stages.

Vembar SS, Macpherson CR, Sismeiro O, Coppée JY, Scherf A.

Genome Biol. 2015 Sep 28;16:212. doi: 10.1186/s13059-015-0771-5.


Flexible guide-RNA design for CRISPR applications using Protospacer Workbench.

MacPherson CR, Scherf A.

Nat Biotechnol. 2015 Aug;33(8):805-6. doi: 10.1038/nbt.3291. Epub 2015 Jun 29. No abstract available.


Original 2-(3-Alkoxy-1H-pyrazol-1-yl)azines Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH).

Lucas-Hourani M, Munier-Lehmann H, El Mazouni F, Malmquist NA, Harpon J, Coutant EP, Guillou S, Helynck O, Noel A, Scherf A, Phillips MA, Tangy F, Vidalain PO, Janin YL.

J Med Chem. 2015 Jul 23;58(14):5579-98. doi: 10.1021/acs.jmedchem.5b00606. Epub 2015 Jun 30.


First efficient CRISPR-Cas9-mediated genome editing in Leishmania parasites.

Sollelis L, Ghorbal M, MacPherson CR, Martins RM, Kuk N, Crobu L, Bastien P, Scherf A, Lopez-Rubio JJ, Sterkers Y.

Cell Microbiol. 2015 Oct;17(10):1405-12. doi: 10.1111/cmi.12456. Epub 2015 Jun 19.


RNase II: A new player enters the game.

Zhang Q, Scherf A.

RNA Biol. 2015;12(6):586-9. doi: 10.1080/15476286.2015.1038013.


Post-translational protein modifications in malaria parasites.

Doerig C, Rayner JC, Scherf A, Tobin AB.

Nat Rev Microbiol. 2015 Mar;13(3):160-72. doi: 10.1038/nrmicro3402. Epub 2015 Feb 9. Review.


Cellular microbiology editorial letter.

Scherf A, Grinstein S.

Cell Microbiol. 2015 Jan;17(1):1. doi: 10.1111/cmi.12402. No abstract available.


Histone methyltransferase inhibitors are orally bioavailable, fast-acting molecules with activity against different species causing malaria in humans.

Malmquist NA, Sundriyal S, Caron J, Chen P, Witkowski B, Menard D, Suwanarusk R, Renia L, Nosten F, Jiménez-Díaz MB, Angulo-Barturen I, Santos Martínez M, Ferrer S, Sanz LM, Gamo FJ, Wittlin S, Duffy S, Avery VM, Ruecker A, Delves MJ, Sinden RE, Fuchter MJ, Scherf A.

Antimicrob Agents Chemother. 2015 Feb;59(2):950-9. doi: 10.1128/AAC.04419-14. Epub 2014 Nov 24.


P. berghei telomerase subunit TERT is essential for parasite survival.

Religa AA, Ramesar J, Janse CJ, Scherf A, Waters AP.

PLoS One. 2014 Oct 2;9(9):e108930. doi: 10.1371/journal.pone.0108930. eCollection 2014.


Development of diaminoquinazoline histone lysine methyltransferase inhibitors as potent blood-stage antimalarial compounds.

Sundriyal S, Malmquist NA, Caron J, Blundell S, Liu F, Chen X, Srimongkolpithak N, Jin J, Charman SA, Scherf A, Fuchter MJ.

ChemMedChem. 2014 Oct;9(10):2360-73. doi: 10.1002/cmdc.201402098. Epub 2014 Jul 9.


Exonuclease-mediated degradation of nascent RNA silences genes linked to severe malaria.

Zhang Q, Siegel TN, Martins RM, Wang F, Cao J, Gao Q, Cheng X, Jiang L, Hon CC, Scheidig-Benatar C, Sakamoto H, Turner L, Jensen AT, Claes A, Guizetti J, Malmquist NA, Scherf A.

Nature. 2014 Sep 18;513(7518):431-5. doi: 10.1038/nature13468. Epub 2014 Jun 29.


Noncoding RNAs as emerging regulators of Plasmodium falciparum virulence gene expression.

Vembar SS, Scherf A, Siegel TN.

Curr Opin Microbiol. 2014 Aug;20:153-61. doi: 10.1016/j.mib.2014.06.013. Epub 2014 Jul 12. Review.


Genome editing in the human malaria parasite Plasmodium falciparum using the CRISPR-Cas9 system.

Ghorbal M, Gorman M, Macpherson CR, Martins RM, Scherf A, Lopez-Rubio JJ.

Nat Biotechnol. 2014 Aug;32(8):819-21. doi: 10.1038/nbt.2925. Epub 2014 Jun 1.


Biology of the malaria parasite--on the special issue for the 10th BioMalPar conference.

Frischknecht F, Mota M, Scherf A, Waters A.

Cell Microbiol. 2014 May;16(5):599-601. doi: 10.1111/cmi.12295. No abstract available.


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