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Items: 1 to 20 of 214

1.

Progress toward inhibitors of metallo-β-lactamases.

McGeary RP, Tan DT, Schenk G.

Future Med Chem. 2017 May 15. doi: 10.4155/fmc-2017-0007. [Epub ahead of print]

PMID:
28504895
2.

Is CuII Coordinated to Patellamides inside Prochloron Cells?

Comba P, Eisenschmidt A, Gahan LR, Herten DP, Nette G, Schenk G, Seefeld M.

Chemistry. 2017 Mar 24. doi: 10.1002/chem.201700895. [Epub ahead of print]

PMID:
28339125
3.

Unique spectral signatures of the nucleic acid dye acridine orange can distinguish cell death by apoptosis and necroptosis.

Plemel JR, Caprariello AV, Keough MB, Henry TJ, Tsutsui S, Chu TH, Schenk GJ, Klaver R, Yong VW, Stys PK.

J Cell Biol. 2017 Apr 3;216(4):1163-1181. doi: 10.1083/jcb.201602028. Epub 2017 Mar 6.

PMID:
28264914
4.

Visualization of the Reaction Trajectory and Transition State in a Hydrolytic Reaction Catalyzed by a Metalloenzyme.

Selleck C, Clayton D, Gahan LR, Mitić N, McGeary RP, Pedroso MM, Guddat LW, Schenk G.

Chemistry. 2017 Apr 6;23(20):4778-4781. doi: 10.1002/chem.201700866. Epub 2017 Mar 23.

PMID:
28261912
5.

Structural basis of the interaction between the putative adhesion-involved and iron-regulated FrpD and FrpC proteins of Neisseria meningitidis.

Sviridova E, Rezacova P, Bondar A, Veverka V, Novak P, Schenk G, Svergun DI, Kuta Smatanova I, Bumba L.

Sci Rep. 2017 Jan 13;7:40408. doi: 10.1038/srep40408.

6.

Insights into an evolutionary strategy leading to antibiotic resistance.

Hou CD, Liu JW, Collyer C, Mitić N, Pedroso MM, Schenk G, Ollis DL.

Sci Rep. 2017 Jan 11;7:40357. doi: 10.1038/srep40357.

7.

Altered blood-brain barrier transport in neuro-inflammatory disorders.

Schenk GJ, de Vries HE.

Drug Discov Today Technol. 2016 Jun;20:5-11. doi: 10.1016/j.ddtec.2016.07.002. Epub 2016 Oct 17. Review.

PMID:
27986224
8.

Enhancement of antibiotic-activity through complexation with metal ions - Combined ITC, NMR, enzymatic and biological studies.

Möhler JS, Kolmar T, Synnatschke K, Hergert M, Wilson LA, Ramu S, Elliott AG, Blaskovich MA, Sidjabat HE, Paterson DL, Schenk G, Cooper MA, Ziora ZM.

J Inorg Biochem. 2017 Feb;167:134-141. doi: 10.1016/j.jinorgbio.2016.11.028. Epub 2016 Nov 24.

PMID:
27984786
9.

Product release is rate-limiting for catalytic processing by the Dengue virus protease.

Shannon AE, Pedroso MM, Chappell KJ, Watterson D, Liebscher S, Kok WM, Fairlie DP, Schenk G, Young PR.

Sci Rep. 2016 Nov 29;6:37539. doi: 10.1038/srep37539.

10.

Mammalian agmatinases constitute unusual members in the family of Mn2+-dependent ureahydrolases.

Romero N, Benítez J, Garcia D, González A, Bennun L, García-Robles MA, López V, Wilson LA, Schenk G, Carvajal N, Uribe E.

J Inorg Biochem. 2017 Jan;166:122-125. doi: 10.1016/j.jinorgbio.2016.11.015. Epub 2016 Nov 9.

PMID:
27846445
11.

Angular correlations of photons from solution diffraction at a free-electron laser encode molecular structure.

Mendez D, Watkins H, Qiao S, Raines KS, Lane TJ, Schenk G, Nelson G, Subramanian G, Tono K, Joti Y, Yabashi M, Ratner D, Doniach S.

IUCrJ. 2016 Sep 26;3(Pt 6):420-429. eCollection 2016 Nov 1.

12.

Preface.

Gahan L, Comba P, Schenk G, Daumann L, Hambley T, Berners-Price S.

J Inorg Biochem. 2016 Sep;162:162-163. doi: 10.1016/j.jinorgbio.2016.09.011. No abstract available.

PMID:
27816087
13.

Metallohydrolase biomimetics with catalytic and structural flexibility.

Mendes LL, Englert D, Fernandes C, Gahan LR, Schenk G, Horn A.

Dalton Trans. 2016 Nov 22;45(46):18510-18521.

PMID:
27805706
14.

AIM-1: An Antibiotic-Degrading Metallohydrolase That Displays Mechanistic Flexibility.

Selleck C, Larrabee JA, Harmer J, Guddat LW, Mitić N, Helweh W, Ollis DL, Craig WR, Tierney DL, Monteiro Pedroso M, Schenk G.

Chemistry. 2016 Dec 5;22(49):17704-17714. doi: 10.1002/chem.201602762. Epub 2016 Oct 25.

PMID:
27778387
15.

Metal Ions Play an Essential Catalytic Role in the Mechanism of Ketol-Acid Reductoisomerase.

Tadrowski S, Pedroso MM, Sieber V, Larrabee JA, Guddat LW, Schenk G.

Chemistry. 2016 May 23;22(22):7427-36. doi: 10.1002/chem.201600620. Epub 2016 May 2.

PMID:
27136273
16.

Potential for measurement of the distribution of DNA folds in complex environments using Correlated X-ray Scattering.

Schenk G, Krajina B, Spakowitz A, Doniach S.

Mod Phys Lett B. 2016 Mar 30;30(8). pii: 1650117. Epub 2015 Dec 29.

17.

Demyelination induces transport of ribosome-containing vesicles from glia to axons: evidence from animal models and MS patient brains.

Shakhbazau A, Schenk GJ, Hay C, Kawasoe J, Klaver R, Yong VW, Geurts JJ, van Minnen J.

Mol Biol Rep. 2016 Jun;43(6):495-507. doi: 10.1007/s11033-016-3990-2. Epub 2016 Apr 26.

PMID:
27115494
18.

Design, synthesis, and in vitro and biological evaluation of potent amino acid-derived thiol inhibitors of the metallo-β-lactamase IMP-1.

Arjomandi OK, Hussein WM, Vella P, Yusof Y, Sidjabat HE, Schenk G, McGeary RP.

Eur J Med Chem. 2016 May 23;114:318-27. doi: 10.1016/j.ejmech.2016.03.017. Epub 2016 Mar 9.

PMID:
27017264
19.

Investigation of the identity of the nucleophile initiating the hydrolysis of phosphate esters catalyzed by dinuclear mimics of metallohydrolases.

Brown JJ, Gahan LR, Schöffler A, Krenske EH, Schenk G.

J Inorg Biochem. 2016 Sep;162:356-365. doi: 10.1016/j.jinorgbio.2016.02.008. Epub 2016 Feb 13.

PMID:
26947012
20.

Captopril analogues as metallo-β-lactamase inhibitors.

Yusof Y, Tan DT, Arjomandi OK, Schenk G, McGeary RP.

Bioorg Med Chem Lett. 2016 Mar 15;26(6):1589-93. doi: 10.1016/j.bmcl.2016.02.007. Epub 2016 Feb 4.

PMID:
26883147

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