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Items: 1 to 20 of 86


Disruption of TFGβ-SMAD3 pathway by the nuclear receptor SHP mediates the antifibrotic activities of BAR704, a novel highly selective FXR ligand.

Carino A, Biagioli M, Marchianò S, Scarpelli P, Zampella A, Limongelli V, Fiorucci S.

Pharmacol Res. 2018 Mar 9;131:17-31. doi: 10.1016/j.phrs.2018.02.033. [Epub ahead of print]


Melatonin activate FIS1, DYN1 and DYN2 Plasmodium falciparum related-genes for mitochondria fission: mitoemerald-GFP as a tool to visualize mitochondria structure.

Scarpelli P, Almeida GT, Viçoso KL, Lima WR, Pereira LB, Meissner KA, Wrenger C, Rafaello A, Rizzuto R, Pozzan T, Garcia CRS.

J Pineal Res. 2018 Feb 26. doi: 10.1111/jpi.12484. [Epub ahead of print]


Genome-wide analysis of the human malaria parasite Plasmodium falciparum transcription factor PfNF-YB shows interaction with a CCAAT motif.

Lima WR, Martins DC, Parreira KS, Scarpelli P, Santos de Moraes M, Topalis P, Hashimoto RF, Garcia CRS.

Oncotarget. 2017 Dec 9;8(69):113987-114001. doi: 10.18632/oncotarget.23053. eCollection 2017 Dec 26.


Gpbar1 agonism promotes a Pgc-1α-dependent browning of white adipose tissue and energy expenditure and reverses diet-induced steatohepatitis in mice.

Carino A, Cipriani S, Marchianò S, Biagioli M, Scarpelli P, Zampella A, Monti MC, Fiorucci S.

Sci Rep. 2017 Oct 20;7(1):13689. doi: 10.1038/s41598-017-13102-y.


ROS-independent Nrf2 activation in prostate cancer.

Bellezza I, Scarpelli P, Pizzo SV, Grottelli S, Costanzi E, Minelli A.

Oncotarget. 2017 Jun 28;8(40):67506-67518. doi: 10.18632/oncotarget.18724. eCollection 2017 Sep 15.


Metabolic Variability of a Multispecies Probiotic Preparation Impacts on the Anti-inflammatory Activity.

Biagioli M, Laghi L, Carino A, Cipriani S, Distrutti E, Marchianò S, Parolin C, Scarpelli P, Vitali B, Fiorucci S.

Front Pharmacol. 2017 Jul 28;8:505. doi: 10.3389/fphar.2017.00505. eCollection 2017.


Nanotraps with biomimetic surface as decoys for chemokines.

Guryanov I, Cipriani S, Fiorucci S, Zashikhina N, Marchianò S, Scarpelli P, Korzhikov-Vlakh V, Popova E, Korzhikova-Vlakh E, Biondi B, Formaggio F, Tennikova T.

Nanomedicine. 2017 Nov;13(8):2575-2585. doi: 10.1016/j.nano.2017.07.006. Epub 2017 Jul 26.


The Bile Acid Receptor GPBAR1 Regulates the M1/M2 Phenotype of Intestinal Macrophages and Activation of GPBAR1 Rescues Mice from Murine Colitis.

Biagioli M, Carino A, Cipriani S, Francisci D, Marchianò S, Scarpelli P, Sorcini D, Zampella A, Fiorucci S.

J Immunol. 2017 Jul 15;199(2):718-733. doi: 10.4049/jimmunol.1700183. Epub 2017 Jun 12.


Selected cholesterol biosynthesis inhibitors produce accumulation of the intermediate FF-MAS that targets nucleus and activates LXRα in HepG2 cells.

Gatticchi L, Cerra B, Scarpelli P, Macchioni L, Sebastiani B, Gioiello A, Roberti R.

Biochim Biophys Acta. 2017 Sep;1862(9):842-852. doi: 10.1016/j.bbalip.2017.05.004. Epub 2017 May 9.


Peroxynitrite Activates the NLRP3 Inflammasome Cascade in SOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis.

Bellezza I, Grottelli S, Costanzi E, Scarpelli P, Pigna E, Morozzi G, Mezzasoma L, Peirce MJ, Moresi V, Adamo S, Minelli A.

Mol Neurobiol. 2018 Mar;55(3):2350-2361. doi: 10.1007/s12035-017-0502-x. Epub 2017 Mar 29.


Biliverdin targets enolase and eukaryotic initiation factor 2 (eIF2α) to reduce the growth of intraerythrocytic development of the malaria parasite Plasmodium falciparum.

Alves E, Maluf FV, Bueno VB, Guido RV, Oliva G, Singh M, Scarpelli P, Costa F, Sartorello R, Catalani LH, Brady D, Tewari R, Garcia CR.

Sci Rep. 2016 Feb 26;6:22093. doi: 10.1038/srep22093.


An update in varicose vein pathology after ten years of endovenous laser therapy (EVLT) with a 980 nm diode laser: clinical experience of a single center.

Scarpelli P, Maggipinto A, Leopardi M, Di Marco E, Disabato A, Boschetti M, Sbenaglia G, Spartera C, Ventura M.

Laser Ther. 2013 Dec 30;22(4):269-73. doi: 10.5978/islsm.13-OR-22.


Predictors and clinical significance of progression or regression of asymptomatic carotid stenosis.

Kakkos SK, Nicolaides AN, Charalambous I, Thomas D, Giannopoulos A, Naylor AR, Geroulakos G, Abbott AL; Asymptomatic Carotid Stenosis and Risk of Stroke (ACSRS) Study Group.

J Vasc Surg. 2014 Apr;59(4):956-967.e1. doi: 10.1016/j.jvs.2013.10.073. Epub 2013 Dec 28.


The size of juxtaluminal hypoechoic area in ultrasound images of asymptomatic carotid plaques predicts the occurrence of stroke.

Kakkos SK, Griffin MB, Nicolaides AN, Kyriacou E, Sabetai MM, Tegos T, Makris GC, Thomas DJ, Geroulakos G; Asymptomatic Carotid Stenosis and Risk of Stroke (ACSRS) Study Group.

J Vasc Surg. 2013 Mar;57(3):609-618.e1; discussion 617-8. doi: 10.1016/j.jvs.2012.09.045. Epub 2013 Jan 18.


Asymptomatic internal carotid artery stenosis and cerebrovascular risk stratification.

Nicolaides AN, Kakkos SK, Kyriacou E, Griffin M, Sabetai M, Thomas DJ, Tegos T, Geroulakos G, Labropoulos N, Doré CJ, Morris TP, Naylor R, Abbott AL; Asymptomatic Carotid Stenosis and Risk of Stroke (ACSRS) Study Group.

J Vasc Surg. 2010 Dec;52(6):1486-1496.e1-5. doi: 10.1016/j.jvs.2010.07.021.


10-year stroke prevention after successful carotid endarterectomy for asymptomatic stenosis (ACST-1): a multicentre randomised trial.

Halliday A, Harrison M, Hayter E, Kong X, Mansfield A, Marro J, Pan H, Peto R, Potter J, Rahimi K, Rau A, Robertson S, Streifler J, Thomas D; Asymptomatic Carotid Surgery Trial (ACST) Collaborative Group.

Lancet. 2010 Sep 25;376(9746):1074-84. doi: 10.1016/S0140-6736(10)61197-X.


Silent embolic infarcts on computed tomography brain scans and risk of ipsilateral hemispheric events in patients with asymptomatic internal carotid artery stenosis.

Kakkos SK, Sabetai M, Tegos T, Stevens J, Thomas D, Griffin M, Geroulakos G, Nicolaides AN; Asymptomatic Carotid Stenosis and Risk of Stroke (ACSRS) Study Group.

J Vasc Surg. 2009 Apr;49(4):902-9. doi: 10.1016/j.jvs.2008.10.059. Epub 2009 Feb 15.


Impairment of plasma nitric oxide availability in senescent healthy individuals: apparent involvement of extracellular superoxide dismutase activity.

Di Massimo C, Lo Presti R, Corbacelli C, Pompei A, Scarpelli P, De Amicis D, Caimi G, Tozzi Ciancarelli MG.

Clin Hemorheol Microcirc. 2006;35(1-2):231-7.


Penile duplex pharmaco-ultrasonography of cavernous arteries in men with erectile dysfunction and generalized atherosclerosis.

Bocchio M, Scarpelli P, Necozione S, Pelliccione F, Spartera C, Francavilla F, Francavilla S.

Int J Androl. 2006 Aug;29(4):496-501.


Impaired plasma nitric oxide availability and extracellular superoxide dismutase activity in healthy humans with advancing age.

Di Massimo C, Scarpelli P, Di Lorenzo N, Caimi G, di Orio F, Ciancarelli MG.

Life Sci. 2006 Feb 9;78(11):1163-7. Epub 2005 Oct 7.


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