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Items: 1 to 20 of 57

1.

Corrigendum: Analysis of the common genetic component of large-vessel vasculitides through a meta-Immunochip strategy.

Carmona FD, Coit P, Saruhan-Direskeneli G, Hernández-Rodríguez J, Cid MC, Solans R, Castañeda S, Vaglio A, Direskeneli H, Merkel PA, Boiardi L, Salvarani C, González-Gay MA, Martín J, Sawalha AH; Spanish GCA Study Group.; Italian GCA Study Group.; Turkish Takayasu Study Group.; Vasculitis Clinical Research Consortium..

Sci Rep. 2017 Apr 5;7:46012. doi: 10.1038/srep46012. No abstract available.

2.

Analysis of the common genetic component of large-vessel vasculitides through a meta-Immunochip strategy.

Carmona FD, Coit P, Saruhan-Direskeneli G, Hernández-Rodríguez J, Cid MC, Solans R, Castañeda S, Vaglio A, Direskeneli H, Merkel PA, Boiardi L, Salvarani C, González-Gay MA, Martín J, Sawalha AH; Spanish GCA Study Group.; Italian GCA Study Group.; Turkish Takayasu Study Group.; Vasculitis Clinical Research Consortium..

Sci Rep. 2017 Mar 9;7:43953. doi: 10.1038/srep43953.

3.

Genome-wide profiling identifies associations between lupus nephritis and differential methylation of genes regulating tissue hypoxia and type 1 interferon responses.

Mok A, Solomon O, Nayak RR, Coit P, Quach HL, Nititham J, Sawalha AH, Barcellos LF, Criswell LA, Chung SA.

Lupus Sci Med. 2016 Dec 7;3(1):e000183. doi: 10.1136/lupus-2016-000183. eCollection 2016.

4.

Histone H2AX phosphorylation as a measure of DNA double-strand breaks and a marker of environmental stress and disease activity in lupus.

Namas R, Renauer P, Ognenovski M, Tsou PS, Sawalha AH.

Lupus Sci Med. 2016 Apr 29;3(1):e000148. doi: 10.1136/lupus-2016-000148. eCollection 2016.

5.

Ethnicity-specific epigenetic variation in naïve CD4+ T cells and the susceptibility to autoimmunity.

Coit P, Ognenovski M, Gensterblum E, Maksimowicz-McKinnon K, Wren JD, Sawalha AH.

Epigenetics Chromatin. 2015 Nov 24;8:49. doi: 10.1186/s13072-015-0037-1. eCollection 2015.

6.

Systemic lupus erythematosus complicated by diffuse alveolar haemorrhage: risk factors, therapy and survival.

Kazzaz NM, Coit P, Lewis EE, McCune WJ, Sawalha AH, Knight JS.

Lupus Sci Med. 2015 Sep 23;2(1):e000117. doi: 10.1136/lupus-2015-000117. eCollection 2015.

7.

DNA methylation patterns in naïve CD4+ T cells identify epigenetic susceptibility loci for malar rash and discoid rash in systemic lupus erythematosus.

Renauer P, Coit P, Jeffries MA, Merrill JT, McCune WJ, Maksimowicz-McKinnon K, Sawalha AH.

Lupus Sci Med. 2015 Sep 15;2(1):e000101. doi: 10.1136/lupus-2015-000101. eCollection 2015.

8.

Renal involvement in lupus is characterized by unique DNA methylation changes in naïve CD4+ T cells.

Coit P, Renauer P, Jeffries MA, Merrill JT, McCune WJ, Maksimowicz-McKinnon K, Sawalha AH.

J Autoimmun. 2015 Jul;61:29-35. doi: 10.1016/j.jaut.2015.05.003. Epub 2015 May 23.

9.

T cell PKCδ kinase inactivation induces lupus-like autoimmunity in mice.

Gorelik G, Sawalha AH, Patel D, Johnson K, Richardson B.

Clin Immunol. 2015 Jun;158(2):193-203. doi: 10.1016/j.clim.2015.03.017. Epub 2015 Mar 28.

10.

Epigenome profiling reveals significant DNA demethylation of interferon signature genes in lupus neutrophils.

Coit P, Yalavarthi S, Ognenovski M, Zhao W, Hasni S, Wren JD, Kaplan MJ, Sawalha AH.

J Autoimmun. 2015 Apr;58:59-66. doi: 10.1016/j.jaut.2015.01.004. Epub 2015 Jan 28.

11.

Identification of Susceptibility Loci in IL6, RPS9/LILRB3, and an Intergenic Locus on Chromosome 21q22 in Takayasu Arteritis in a Genome-Wide Association Study.

Renauer PA, Saruhan-Direskeneli G, Coit P, Adler A, Aksu K, Keser G, Alibaz-Oner F, Aydin SZ, Kamali S, Inanc M, Carette S, Cuthbertson D, Hoffman GS, Akar S, Onen F, Akkoc N, Khalidi NA, Koening C, Karadag O, Kiraz S, Langford CA, Maksimowicz-McKinnon K, McAlear CA, Ozbalkan Z, Ates A, Karaaslan Y, Duzgun N, Monach PA, Ozer HT, Erken E, Ozturk MA, Yazici A, Cefle A, Onat AM, Kisacik B, Pagnoux C, Kasifoglu T, Seyahi E, Fresko I, Seo P, Sreih AG, Warrington KJ, Ytterberg SR, Cobankara V, Cunninghame-Graham DS, Vyse TJ, Pamuk ON, Tunc SE, Dalkilic E, Bicakcigil M, Yentur SP, Wren JD, Merkel PA, Direskeneli H, Sawalha AH.

Arthritis Rheumatol. 2015 May;67(5):1361-8. doi: 10.1002/art.39035.

12.

Autoimmune disease in the epigenetic era: how has epigenetics changed our understanding of disease and how can we expect the field to evolve?

Jeffries MA, Sawalha AH.

Expert Rev Clin Immunol. 2015 Jan;11(1):45-58. doi: 10.1586/1744666X.2015.994507. Review.

13.
14.

Activation of the JAK/STAT pathway in Behcet's disease.

Tulunay A, Dozmorov MG, Ture-Ozdemir F, Yilmaz V, Eksioglu-Demiralp E, Alibaz-Oner F, Ozen G, Wren JD, Saruhan-Direskeneli G, Sawalha AH, Direskeneli H.

Genes Immun. 2015 Mar;16(2):170-5. doi: 10.1038/gene.2014.64. Epub 2014 Nov 20. Erratum in: Genes Immun. 2015 Mar;16(2):176.

15.

Genome-wide DNA methylation analysis in dermal fibroblasts from patients with diffuse and limited systemic sclerosis reveals common and subset-specific DNA methylation aberrancies.

Altorok N, Tsou PS, Coit P, Khanna D, Sawalha AH.

Ann Rheum Dis. 2015 Aug;74(8):1612-20. doi: 10.1136/annrheumdis-2014-205303. Epub 2014 May 8.

16.

Epigenome-wide scan identifies a treatment-responsive pattern of altered DNA methylation among cytoskeletal remodeling genes in monocytes and CD4+ T cells from patients with Behçet's disease.

Hughes T, Ture-Ozdemir F, Alibaz-Oner F, Coit P, Direskeneli H, Sawalha AH.

Arthritis Rheumatol. 2014 Jun;66(6):1648-58. doi: 10.1002/art.38409.

17.

Genome-wide DNA methylation patterns in naive CD4+ T cells from patients with primary Sjögren's syndrome.

Altorok N, Coit P, Hughes T, Koelsch KA, Stone DU, Rasmussen A, Radfar L, Scofield RH, Sivils KL, Farris AD, Sawalha AH.

Arthritis Rheumatol. 2014 Mar;66(3):731-9. doi: 10.1002/art.38264.

18.

Trans-ancestral studies fine map the SLE-susceptibility locus TNFSF4.

Manku H, Langefeld CD, Guerra SG, Malik TH, Alarcon-Riquelme M, Anaya JM, Bae SC, Boackle SA, Brown EE, Criswell LA, Freedman BI, Gaffney PM, Gregersen PA, Guthridge JM, Han SH, Harley JB, Jacob CO, James JA, Kamen DL, Kaufman KM, Kelly JA, Martin J, Merrill JT, Moser KL, Niewold TB, Park SY, Pons-Estel BA, Sawalha AH, Scofield RH, Shen N, Stevens AM, Sun C, Gilkeson GS, Edberg JC, Kimberly RP, Nath SK, Tsao BP, Vyse TJ.

PLoS Genet. 2013;9(7):e1003554. doi: 10.1371/journal.pgen.1003554. Epub 2013 Jul 18.

19.

Overexpression of methyl-CpG-binding protein 2 and autoimmunity: evidence from MECP2 duplication syndrome, lupus, MECP2 transgenic and Mecp2 deficient mice.

Sawalha AH.

Lupus. 2013 Aug;22(9):870-2. doi: 10.1177/0961203313497119. Epub 2013 Jul 16. No abstract available.

20.

Identification of multiple genetic susceptibility loci in Takayasu arteritis.

Saruhan-Direskeneli G, Hughes T, Aksu K, Keser G, Coit P, Aydin SZ, Alibaz-Oner F, Kamalı S, Inanc M, Carette S, Hoffman GS, Akar S, Onen F, Akkoc N, Khalidi NA, Koening C, Karadag O, Kiraz S, Langford CA, McAlear CA, Ozbalkan Z, Ates A, Karaaslan Y, Maksimowicz-McKinnon K, Monach PA, Ozer HT, Seyahi E, Fresko I, Cefle A, Seo P, Warrington KJ, Ozturk MA, Ytterberg SR, Cobankara V, Onat AM, Guthridge JM, James JA, Tunc E, Duzgun N, Bıcakcıgil M, Yentür SP, Merkel PA, Direskeneli H, Sawalha AH.

Am J Hum Genet. 2013 Aug 8;93(2):298-305. doi: 10.1016/j.ajhg.2013.05.026. Epub 2013 Jul 3.

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