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Items: 1 to 20 of 28


Origin and phylogenetic status of the local Ashanti Dwarf pig (ADP) of Ghana based on genetic analysis.

Osei-Amponsah R, Skinner BM, Adjei DO, Bauer J, Larson G, Affara NA, Sargent CA.

BMC Genomics. 2017 Feb 20;18(1):193. doi: 10.1186/s12864-017-3536-6.


The pig X and Y Chromosomes: structure, sequence, and evolution.

Skinner BM, Sargent CA, Churcher C, Hunt T, Herrero J, Loveland JE, Dunn M, Louzada S, Fu B, Chow W, Gilbert J, Austin-Guest S, Beal K, Carvalho-Silva D, Cheng W, Gordon D, Grafham D, Hardy M, Harley J, Hauser H, Howden P, Howe K, Lachani K, Ellis PJ, Kelly D, Kerry G, Kerwin J, Ng BL, Threadgold G, Wileman T, Wood JM, Yang F, Harrow J, Affara NA, Tyler-Smith C.

Genome Res. 2016 Jan;26(1):130-9. doi: 10.1101/gr.188839.114. Epub 2015 Nov 11.


Expansion of the HSFY gene family in pig lineages : HSFY expansion in suids.

Skinner BM, Lachani K, Sargent CA, Yang F, Ellis P, Hunt T, Fu B, Louzada S, Churcher C, Tyler-Smith C, Affara NA.

BMC Genomics. 2015 Jun 9;16:442. doi: 10.1186/s12864-015-1650-x.


Thrifty metabolic programming in rats is induced by both maternal undernutrition and postnatal leptin treatment, but masked in the presence of both: implications for models of developmental programming.

Ellis PJ, Morris TJ, Skinner BM, Sargent CA, Vickers MH, Gluckman PD, Gilmour S, Affara NA.

BMC Genomics. 2014 Jan 21;15:49. doi: 10.1186/1471-2164-15-49.


Regions of XY homology in the pig X chromosome and the boundary of the pseudoautosomal region.

Skinner BM, Lachani K, Sargent CA, Affara NA.

BMC Genet. 2013 Jan 15;14:3. doi: 10.1186/1471-2156-14-3.


Biochemical and pharmacological characterization of AZD1981, an orally available selective DP2 antagonist in clinical development for asthma.

Schmidt JA, Bell FM, Akam E, Marshall C, Dainty IA, Heinemann A, Dougall IG, Bonnert RV, Sargent CA.

Br J Pharmacol. 2013 Apr;168(7):1626-38. doi: 10.1111/bph.12053.


Gene structure and expression of serotonin receptor HTR2C in hypothalamic samples from infanticidal and control sows.

Quilter CR, Bagga M, Moinie A, Junaid F, Sargent CA.

BMC Neurosci. 2012 Apr 2;13:37. doi: 10.1186/1471-2202-13-37.


Gene expression profiling in the lungs of pigs with different susceptibilities to Glässer's disease.

Wilkinson JM, Sargent CA, Galina-Pantoja L, Tucker AW.

BMC Genomics. 2010 Jul 29;11:455. doi: 10.1186/1471-2164-11-455.


Analysis of X chromosome genomic DNA sequence copy number variation associated with premature ovarian failure (POF).

Quilter CR, Karcanias AC, Bagga MR, Duncan S, Murray A, Conway GS, Sargent CA, Affara NA.

Hum Reprod. 2010 Aug;25(8):2139-50. doi: 10.1093/humrep/deq158. Epub 2010 Jun 22.


The human RPS4 paralogue on Yq11.223 encodes a structurally conserved ribosomal protein and is preferentially expressed during spermatogenesis.

Lopes AM, Miguel RN, Sargent CA, Ellis PJ, Amorim A, Affara NA.

BMC Mol Biol. 2010 May 7;11:33. doi: 10.1186/1471-2199-11-33.


Transcriptional changes in response to X chromosome dosage in the mouse: implications for X inactivation and the molecular basis of Turner Syndrome.

Lopes AM, Burgoyne PS, Ojarikre A, Bauer J, Sargent CA, Amorim A, Affara NA.

BMC Genomics. 2010 Feb 1;11:82. doi: 10.1186/1471-2164-11-82.


Global transcriptional response of pig brain and lung to natural infection by Pseudorabies virus.

Yuan JF, Zhang SJ, Jafer O, Furlong RA, Chausiaux OE, Sargent CA, Zhang GH, Affara NA.

BMC Microbiol. 2009 Dec 1;9:246. doi: 10.1186/1471-2180-9-246.


Analysis of sex chromosome abnormalities using X and Y chromosome DNA tiling path arrays.

Karcanias AC, Ichimura K, Mitchell MJ, Sargent CA, Affara NA.

J Med Genet. 2007 Jul;44(7):429-36. Epub 2007 Feb 27.


Triplication of several PAR1 genes and part of the Homo sapiens specific Yp11.2/Xq21.3 region of homology in a 46,X,t(X;Y)(p22.33;p11.2) male with schizophrenia.

Ross NL, Yang J, Sargent CA, Boucher CA, Nanko S, Wadekar R, Williams NA, Affara NA, Crow TJ.

J Med Genet. 2001 Oct;38(10):710-9. No abstract available.


Divergent outcomes of intrachromosomal recombination on the human Y chromosome: male infertility and recurrent polymorphism.

Blanco P, Shlumukova M, Sargent CA, Jobling MA, Affara N, Hurles ME.

J Med Genet. 2000 Oct;37(10):752-8.


Effect of the p38 kinase inhibitor, SB 203580, on allergic airway inflammation in the rat.

Escott KJ, Belvisi MG, Birrell MA, Webber SE, Foster ML, Sargent CA.

Br J Pharmacol. 2000 Sep;131(2):173-6.


Five cases of isolated glycerol kinase deficiency, including two families: failure to find genotype:phenotype correlation.

Sargent CA, Kidd A, Moore S, Dean J, Besley GT, Affara NA.

J Med Genet. 2000 Jun;37(6):434-41.


The critical region of overlap defining the AZFa male infertility interval of proximal Yq contains three transcribed sequences.

Sargent CA, Boucher CA, Kirsch S, Brown G, Weiss B, Trundley A, Burgoyne P, Saut N, Durand C, Levy N, Terriou P, Hargreave T, Cooke H, Mitchell M, Rappold GA, Affara NA.

J Med Genet. 1999 Sep;36(9):670-7.


An X-linked zinc finger gene mapping to Xq21.1-q21.3 closely related to ZFX and ZFY: possible origins from a common ancestral gene.

Lloyd SL, Sargent CA, Chalmers J, Lim E, Habeebu SS, Affara NA.

Nucleic Acids Res. 1991 Sep 25;19(18):4835-41.

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