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Items: 1 to 20 of 35

1.

Actin dynamics at focal adhesions: a common endpoint and putative therapeutic target for proteinuric kidney diseases.

Sever S, Schiffer M.

Kidney Int. 2018 Jun;93(6):1298-1307. doi: 10.1016/j.kint.2017.12.028. Epub 2018 Apr 17. Review.

PMID:
29678354
2.

Rituximab and Therapeutic Plasma Exchange in Recurrent Focal Segmental Glomerulosclerosis Postkidney Transplantation.

Alasfar S, Matar D, Montgomery RA, Desai N, Lonze B, Vujjini V, Estrella MM, Manllo Dieck J, Khneizer G, Sever S, Reiser J, Alachkar N.

Transplantation. 2018 Mar;102(3):e115-e120. doi: 10.1097/TP.0000000000002008.

PMID:
29189487
3.

Cardiovascular Disease Biomarkers and suPAR in Predicting Decline in Renal Function: A Prospective Cohort Study.

Hayek SS, Ko YA, Awad M, Ahmed H, Gray B, Hosny KM, Aida H, Tracy MJ, Wei C, Sever S, Reiser J, Quyyumi AA.

Kidney Int Rep. 2017 Feb 9;2(3):425-432. doi: 10.1016/j.ekir.2017.02.001. eCollection 2017 May.

4.

Association of Serum Soluble Urokinase Receptor Levels With Progression of Kidney Disease in Children.

Schaefer F, Trachtman H, Wühl E, Kirchner M, Hayek SS, Anarat A, Duzova A, Mir S, Paripovic D, Yilmaz A, Lugani F, Arbeiter K, Litwin M, Oh J, Matteucci MC, Gellermann J, Wygoda S, Jankauskiene A, Klaus G, Dusek J, Testa S, Zurowska A, Caldas Afonso A, Tracy M, Wei C, Sever S, Smoyer W, Reiser J; ESCAPE Trial Consortium and the 4C Study Group.

JAMA Pediatr. 2017 Nov 6;171(11):e172914. doi: 10.1001/jamapediatrics.2017.2914. Epub 2017 Nov 6.

5.

A tripartite complex of suPAR, APOL1 risk variants and αvβ3 integrin on podocytes mediates chronic kidney disease.

Hayek SS, Koh KH, Grams ME, Wei C, Ko YA, Li J, Samelko B, Lee H, Dande RR, Lee HW, Hahm E, Peev V, Tracy M, Tardi NJ, Gupta V, Altintas MM, Garborcauskas G, Stojanovic N, Winkler CA, Lipkowitz MS, Tin A, Inker LA, Levey AS, Zeier M, Freedman BI, Kopp JB, Skorecki K, Coresh J, Quyyumi AA, Sever S, Reiser J.

Nat Med. 2017 Aug;23(8):945-953. doi: 10.1038/nm.4362. Epub 2017 Jun 26.

6.

Soluble Urokinase Plasminogen Activator Receptor and Outcomes in Patients with Diabetes on Hemodialysis.

Drechsler C, Hayek SS, Wei C, Sever S, Genser B, Krane V, Meinitzer A, März W, Wanner C, Reiser J.

Clin J Am Soc Nephrol. 2017 Aug 7;12(8):1265-1273. doi: 10.2215/CJN.10881016. Epub 2017 May 11.

7.

Drugs targeting dynamin can restore cytoskeleton and focal contact alterations of urinary podocytes derived from patients with nephrotic syndrome.

Müller-Deile J, Teng B, Schenk H, Haller H, Reiser J, Sever S, Schiffer M.

Ann Transl Med. 2016 Nov;4(21):439. No abstract available.

8.

Bone marrow-derived immature myeloid cells are a main source of circulating suPAR contributing to proteinuric kidney disease.

Hahm E, Wei C, Fernandez I, Li J, Tardi NJ, Tracy M, Wadhwani S, Cao Y, Peev V, Zloza A, Lusciks J, Hayek SS, O'Connor C, Bitzer M, Gupta V, Sever S, Sykes DB, Scadden DT, Reiser J.

Nat Med. 2017 Jan;23(1):100-106. doi: 10.1038/nm.4242. Epub 2016 Dec 12.

9.

Anks1a regulates COPII-mediated anterograde transport of receptor tyrosine kinases critical for tumorigenesis.

Lee H, Noh H, Mun J, Gu C, Sever S, Park S.

Nat Commun. 2016 Sep 13;7:12799. doi: 10.1038/ncomms12799.

10.

Dynamin Autonomously Regulates Podocyte Focal Adhesion Maturation.

Gu C, Lee HW, Garborcauskas G, Reiser J, Gupta V, Sever S.

J Am Soc Nephrol. 2017 Feb;28(2):446-451. doi: 10.1681/ASN.2016010008. Epub 2016 Jul 18.

11.

Soluble Urokinase Receptor and Chronic Kidney Disease.

Hayek SS, Sever S, Ko YA, Trachtman H, Awad M, Wadhwani S, Altintas MM, Wei C, Hotton AL, French AL, Sperling LS, Lerakis S, Quyyumi AA, Reiser J.

N Engl J Med. 2015 Nov 12;373(20):1916-25. doi: 10.1056/NEJMoa1506362. Epub 2015 Nov 5.

12.

CD2AP, dendrin, and cathepsin L in the kidney.

Sever S, Reiser J.

Am J Pathol. 2015 Nov;185(11):3129-30. doi: 10.1016/j.ajpath.2015.06.022. No abstract available.

13.

Pharmacological targeting of actin-dependent dynamin oligomerization ameliorates chronic kidney disease in diverse animal models.

Schiffer M, Teng B, Gu C, Shchedrina VA, Kasaikina M, Pham VA, Hanke N, Rong S, Gueler F, Schroder P, Tossidou I, Park JK, Staggs L, Haller H, Erschow S, Hilfiker-Kleiner D, Wei C, Chen C, Tardi N, Hakroush S, Selig MK, Vasilyev A, Merscher S, Reiser J, Sever S.

Nat Med. 2015 Jun;21(6):601-9. doi: 10.1038/nm.3843. Epub 2015 May 11.

14.

A Podocyte-Based Automated Screening Assay Identifies Protective Small Molecules.

Lee HW, Khan SQ, Faridi MH, Wei C, Tardi NJ, Altintas MM, Elshabrawy HA, Mangos S, Quick KL, Sever S, Reiser J, Gupta V.

J Am Soc Nephrol. 2015 Nov;26(11):2741-52. doi: 10.1681/ASN.2014090859. Epub 2015 Apr 9.

15.

The grand challenge of nephrology.

Trachtman H, Benzing T, Sever S, Harris RC, Reiser J.

Front Med (Lausanne). 2014 Sep 18;1:28. doi: 10.3389/fmed.2014.00028. eCollection 2014. No abstract available.

16.

Regulation of dynamin oligomerization in cells: the role of dynamin-actin interactions and its GTPase activity.

Gu C, Chang J, Shchedrina VA, Pham VA, Hartwig JH, Suphamungmee W, Lehman W, Hyman BT, Bacskai BJ, Sever S.

Traffic. 2014 Aug;15(8):819-38. doi: 10.1111/tra.12178. Epub 2014 Jun 24.

17.

Reduction of proteinuria through podocyte alkalinization.

Altintas MM, Moriwaki K, Wei C, Möller CC, Flesche J, Li J, Yaddanapudi S, Faridi MH, Gödel M, Huber TB, Preston RA, Jiang JX, Kerjaschki D, Sever S, Reiser J.

J Biol Chem. 2014 Jun 20;289(25):17454-67. doi: 10.1074/jbc.M114.568998. Epub 2014 May 9.

18.

Signal transduction in podocytes--spotlight on receptor tyrosine kinases.

Reiser J, Sever S, Faul C.

Nat Rev Nephrol. 2014 Feb;10(2):104-15. doi: 10.1038/nrneph.2013.274. Epub 2014 Jan 7. Review.

19.

Transient receptor potential channel 6 (TRPC6) protects podocytes during complement-mediated glomerular disease.

Kistler AD, Singh G, Altintas MM, Yu H, Fernandez IC, Gu C, Wilson C, Srivastava SK, Dietrich A, Walz K, Kerjaschki D, Ruiz P, Dryer S, Sever S, Dinda AK, Faul C, Reiser J.

J Biol Chem. 2013 Dec 20;288(51):36598-609. doi: 10.1074/jbc.M113.488122. Epub 2013 Nov 5.

20.

Dynamin rings: not just for fission.

Sever S, Chang J, Gu C.

Traffic. 2013 Dec;14(12):1194-9. doi: 10.1111/tra.12116. Epub 2013 Sep 19. Review.

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