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Items: 1 to 20 of 28


Migraine-Associated TRESK Mutations Increase Neuronal Excitability through Alternative Translation Initiation and Inhibition of TREK.

Royal P, Andres-Bilbe A, Ávalos Prado P, Verkest C, Wdziekonski B, Schaub S, Baron A, Lesage F, Gasull X, Levitz J, Sandoz G.

Neuron. 2019 Jan 16;101(2):232-245.e6. doi: 10.1016/j.neuron.2018.11.039. Epub 2018 Dec 17.


Dimerization of the voltage-sensing phosphatase controls its voltage-sensing and catalytic activity.

Rayaprolu V, Royal P, Stengel K, Sandoz G, Kohout SC.

J Gen Physiol. 2018 May 7;150(5):683-696. doi: 10.1085/jgp.201812064. Epub 2018 Apr 25.


A Bacterial Toxin with Analgesic Properties: Hyperpolarization of DRG Neurons by Mycolactone.

Song OR, Kim HB, Jouny S, Ricard I, Vandeputte A, Deboosere N, Marion E, Queval CJ, Lesport P, Bourinet E, Henrion D, Oh SB, Lebon G, Sandoz G, Yeramian E, Marsollier L, Brodin P.

Toxins (Basel). 2017 Jul 18;9(7). pii: E227. doi: 10.3390/toxins9070227.


Heterodimerization within the TREK channel subfamily produces a diverse family of highly regulated potassium channels.

Levitz J, Royal P, Comoglio Y, Wdziekonski B, Schaub S, Clemens DM, Isacoff EY, Sandoz G.

Proc Natl Acad Sci U S A. 2016 Apr 12;113(15):4194-9. doi: 10.1073/pnas.1522459113. Epub 2016 Mar 28.


[Mycolactone: the amazing analgesic mycobacterial toxin].

Song OR, Marion E, Comoglio Y, Babonneau J, Guerineau N, Sandoz G, Yeramian E, Brodin P, Marsollier L.

Med Sci (Paris). 2016 Feb;32(2):156-8. doi: 10.1051/medsci/20163202007. Epub 2016 Mar 2. French. No abstract available.


Area-specific development of distinct projection neuron subclasses is regulated by postnatal epigenetic modifications.

Harb K, Magrinelli E, Nicolas CS, Lukianets N, Frangeul L, Pietri M, Sun T, Sandoz G, Grammont F, Jabaudon D, Studer M, Alfano C.

Elife. 2016 Jan 27;5:e09531. doi: 10.7554/eLife.09531.


Phospholipase D2 specifically regulates TREK potassium channels via direct interaction and local production of phosphatidic acid.

Comoglio Y, Levitz J, Kienzler MA, Lesage F, Isacoff EY, Sandoz G.

Proc Natl Acad Sci U S A. 2014 Sep 16;111(37):13547-52. doi: 10.1073/pnas.1407160111. Epub 2014 Sep 2.


Mycobacterial toxin induces analgesia in buruli ulcer by targeting the angiotensin pathways.

Marion E, Song OR, Christophe T, Babonneau J, Fenistein D, Eyer J, Letournel F, Henrion D, Clere N, Paille V, Guérineau NC, Saint André JP, Gersbach P, Altmann KH, Stinear TP, Comoglio Y, Sandoz G, Preisser L, Delneste Y, Yeramian E, Marsollier L, Brodin P.

Cell. 2014 Jun 19;157(7):1565-76. doi: 10.1016/j.cell.2014.04.040.


Baclofen and other GABAB receptor agents are allosteric modulators of the CXCL12 chemokine receptor CXCR4.

Guyon A, Kussrow A, Olmsted IR, Sandoz G, Bornhop DJ, Nahon JL.

J Neurosci. 2013 Jul 10;33(28):11643-54. doi: 10.1523/JNEUROSCI.6070-11.2013.


Optogenetic techniques for the study of native potassium channels.

Sandoz G, Levitz J.

Front Mol Neurosci. 2013 Apr 11;6:6. doi: 10.3389/fnmol.2013.00006. eCollection 2013.


[Optical remote control of native ion channels].

Sandoz G, Isacoff EY.

Med Sci (Paris). 2012 Nov;28(11):934-7. doi: 10.1051/medsci/20122811011. Epub 2012 Nov 12. French. No abstract available.


Optical control of endogenous proteins with a photoswitchable conditional subunit reveals a role for TREK1 in GABA(B) signaling.

Sandoz G, Levitz J, Kramer RH, Isacoff EY.

Neuron. 2012 Jun 21;74(6):1005-14. doi: 10.1016/j.neuron.2012.04.026.


Molecular regulations governing TREK and TRAAK channel functions.

Noël J, Sandoz G, Lesage F.

Channels (Austin). 2011 Sep-Oct;5(5):402-9. doi: 10.4161/chan.5.5.16469. Epub 2011 Sep 1. Review.


Optical probing of a dynamic membrane interaction that regulates the TREK1 channel.

Sandoz G, Bell SC, Isacoff EY.

Proc Natl Acad Sci U S A. 2011 Feb 8;108(6):2605-10. doi: 10.1073/pnas.1015788108. Epub 2011 Jan 24.


Potassium channel silencing by constitutive endocytosis and intracellular sequestration.

Feliciangeli S, Tardy MP, Sandoz G, Chatelain FC, Warth R, Barhanin J, Bendahhou S, Lesage F.

J Biol Chem. 2010 Feb 12;285(7):4798-805. doi: 10.1074/jbc.M109.078535. Epub 2009 Dec 3.


Extracellular acidification exerts opposite actions on TREK1 and TREK2 potassium channels via a single conserved histidine residue.

Sandoz G, Douguet D, Chatelain F, Lazdunski M, Lesage F.

Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14628-33. doi: 10.1073/pnas.0906267106. Epub 2009 Aug 10.


Protein complex analysis of native brain potassium channels by proteomics.

Sandoz G, Lesage F.

Methods Mol Biol. 2008;491:113-23. doi: 10.1007/978-1-59745-526-8_9.


Mtap2 is a constituent of the protein network that regulates twik-related K+ channel expression and trafficking.

Sandoz G, Tardy MP, Thümmler S, Feliciangeli S, Lazdunski M, Lesage F.

J Neurosci. 2008 Aug 20;28(34):8545-52. doi: 10.1523/JNEUROSCI.1962-08.2008.


Does sumoylation control K2P1/TWIK1 background K+ channels?

Feliciangeli S, Bendahhou S, Sandoz G, Gounon P, Reichold M, Warth R, Lazdunski M, Barhanin J, Lesage F.

Cell. 2007 Aug 10;130(3):563-9.


AKAP150, a switch to convert mechano-, pH- and arachidonic acid-sensitive TREK K(+) channels into open leak channels.

Sandoz G, Thümmler S, Duprat F, Feliciangeli S, Vinh J, Escoubas P, Guy N, Lazdunski M, Lesage F.

EMBO J. 2006 Dec 13;25(24):5864-72. Epub 2006 Nov 16.

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