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Items: 1 to 20 of 41


Mycobacterial nucleoid associated proteins: An added dimension in gene regulation.

Kriel NL, Gallant J, van Wyk N, van Helden P, Sampson SL, Warren RM, Williams MJ.

Tuberculosis (Edinb). 2018 Jan;108:169-177. doi: 10.1016/ Epub 2017 Dec 13. Review.


Versatility of 7-Substituted Coumarin Molecules as Antimycobacterial Agents, Neuronal Enzyme Inhibitors and Neuroprotective Agents.

Kapp E, Visser H, Sampson SL, Malan SF, Streicher EM, Foka GB, Warner DF, Omoruyi SI, Enogieru AB, Ekpo OE, Zindo FT, Joubert J.

Molecules. 2017 Sep 30;22(10). pii: E1644. doi: 10.3390/molecules22101644.


Two promoters in the esx-3 gene cluster of Mycobacterium smegmatis respond inversely to different iron concentrations in vitro.

Fang Z, Newton-Foot M, Sampson SL, Gey van Pittius NC.

BMC Res Notes. 2017 Aug 25;10(1):426. doi: 10.1186/s13104-017-2752-0.


Proteogenomic Investigation of Strain Variation in Clinical Mycobacterium tuberculosis Isolates.

Heunis T, Dippenaar A, Warren RM, van Helden PD, van der Merwe RG, Gey van Pittius NC, Pain A, Sampson SL, Tabb DL.

J Proteome Res. 2017 Oct 6;16(10):3841-3851. doi: 10.1021/acs.jproteome.7b00483. Epub 2017 Sep 11.


Exploring the potential of T7 bacteriophage protein Gp2 as a novel inhibitor of mycobacterial RNA polymerase.

du Plessis J, Cloete R, Burchell L, Sarkar P, Warren RM, Christoffels A, Wigneshweraraj S, Sampson SL.

Tuberculosis (Edinb). 2017 Sep;106:82-90. doi: 10.1016/ Epub 2017 Jul 18.


Small Molecule Efflux Pump Inhibitors in Mycobacterium tuberculosis: A Rational Drug Design Perspective.

Kapp E, Malan SF, Joubert J, Sampson SL.

Mini Rev Med Chem. 2018;18(1):72-86. doi: 10.2174/1389557517666170510105506. Review.


Mammalian cell cultures as models for Mycobacterium tuberculosis-human immunodeficiency virus (HIV) interaction studies: A review.

Chingwaru W, Glashoff RH, Vidmar J, Kapewangolo P, Sampson SL.

Asian Pac J Trop Med. 2016 Sep;9(9):832-838. doi: 10.1016/j.apjtm.2016.07.002. Epub 2016 Jul 26. Review.


Prevalence of pyrazinamide resistance across the spectrum of drug resistant phenotypes of Mycobacterium tuberculosis.

Whitfield MG, Streicher EM, Dolby T, Simpson JA, Sampson SL, Van Helden PD, Van Rie A, Warren RM.

Tuberculosis (Edinb). 2016 Jul;99:128-30. doi: 10.1016/ Epub 2016 May 30.


Elucidating population-wide mycobacterial replication dynamics at the single-cell level.

Mouton JM, Helaine S, Holden DW, Sampson SL.

Microbiology. 2016 Jun;162(6):966-78. doi: 10.1099/mic.0.000288. Epub 2016 Mar 30.


The plasmid-mediated evolution of the mycobacterial ESX (Type VII) secretion systems.

Newton-Foot M, Warren RM, Sampson SL, van Helden PD, Gey van Pittius NC.

BMC Evol Biol. 2016 Mar 15;16:62. doi: 10.1186/s12862-016-0631-2.


Recombination in pe/ppe genes contributes to genetic variation in Mycobacterium tuberculosis lineages.

Phelan JE, Coll F, Bergval I, Anthony RM, Warren R, Sampson SL, Gey van Pittius NC, Glynn JR, Crampin AC, Alves A, Bessa TB, Campino S, Dheda K, Grandjean L, Hasan R, Hasan Z, Miranda A, Moore D, Panaiotov S, Perdigao J, Portugal I, Sheen P, de Oliveira Sousa E, Streicher EM, van Helden PD, Viveiros M, Hibberd ML, Pain A, McNerney R, Clark TG.

BMC Genomics. 2016 Feb 29;17:151. doi: 10.1186/s12864-016-2467-y.


Strength in Diversity: Hidden Genetic Depths of Mycobacterium tuberculosis.

Sampson SL.

Trends Microbiol. 2016 Feb;24(2):82-84. doi: 10.1016/j.tim.2015.12.006. Epub 2016 Jan 2.


Whole genome sequence analysis of Mycobacterium suricattae.

Dippenaar A, Parsons SDC, Sampson SL, van der Merwe RG, Drewe JA, Abdallah AM, Siame KK, Gey van Pittius NC, van Helden PD, Pain A, Warren RM.

Tuberculosis (Edinb). 2015 Dec;95(6):682-688. doi: 10.1016/ Epub 2015 Oct 13.


Whole genome sequencing reveals genomic heterogeneity and antibiotic purification in Mycobacterium tuberculosis isolates.

Black PA, de Vos M, Louw GE, van der Merwe RG, Dippenaar A, Streicher EM, Abdallah AM, Sampson SL, Victor TC, Dolby T, Simpson JA, van Helden PD, Warren RM, Pain A.

BMC Genomics. 2015 Oct 24;16:857. doi: 10.1186/s12864-015-2067-2.


Efflux pump inhibitors: targeting mycobacterial efflux systems to enhance TB therapy.

Pule CM, Sampson SL, Warren RM, Black PA, van Helden PD, Victor TC, Louw GE.

J Antimicrob Chemother. 2016 Jan;71(1):17-26. doi: 10.1093/jac/dkv316. Epub 2015 Oct 15. Review.


Molecular Epidemiological Interpretation of the Epidemic of Extensively Drug-Resistant Tuberculosis in South Africa.

Streicher EM, Sampson SL, Dheda K, Dolby T, Simpson JA, Victor TC, Gey van Pittius NC, van Helden PD, Warren RM.

J Clin Microbiol. 2015 Nov;53(11):3650-3. doi: 10.1128/JCM.01414-15. Epub 2015 Sep 2.


Mycobacterium tuberculosis pncA Polymorphisms That Do Not Confer Pyrazinamide Resistance at a Breakpoint Concentration of 100 Micrograms per Milliliter in MGIT.

Whitfield MG, Warren RM, Streicher EM, Sampson SL, Sirgel FA, van Helden PD, Mercante A, Willby M, Hughes K, Birkness K, Morlock G, van Rie A, Posey JE.

J Clin Microbiol. 2015 Nov;53(11):3633-5. doi: 10.1128/JCM.01001-15. Epub 2015 Aug 19.


A Global Perspective on Pyrazinamide Resistance: Systematic Review and Meta-Analysis.

Whitfield MG, Soeters HM, Warren RM, York T, Sampson SL, Streicher EM, van Helden PD, van Rie A.

PLoS One. 2015 Jul 28;10(7):e0133869. doi: 10.1371/journal.pone.0133869. eCollection 2015. Review.


Phylogeny to function: PE/PPE protein evolution and impact on Mycobacterium tuberculosis pathogenicity.

Fishbein S, van Wyk N, Warren RM, Sampson SL.

Mol Microbiol. 2015 Jun;96(5):901-16. doi: 10.1111/mmi.12981. Epub 2015 Mar 30. Review.


Phosphoproteomics analysis of a clinical Mycobacterium tuberculosis Beijing isolate: expanding the mycobacterial phosphoproteome catalog.

Fortuin S, Tomazella GG, Nagaraj N, Sampson SL, Gey van Pittius NC, Soares NC, Wiker HG, de Souza GA, Warren RM.

Front Microbiol. 2015 Feb 10;6:6. doi: 10.3389/fmicb.2015.00006. eCollection 2015.

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