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Retrospective Proteomic Analysis of Cellular Immune Responses and Protective Correlates of p24 Vaccination in an HIV Elite Controller Using Antibody Arrays.

Perera SS, Wang B, Damian A, Dyer W, Zhou L, Conceicao V, Saksena NK.

Microarrays (Basel). 2016 Jun 2;5(2). pii: E14. doi: 10.3390/microarrays5020014.


Differential regulation of cytotoxicity pathway discriminating between HIV, HCV mono- and co-infection identified by transcriptome profiling of PBMCs.

Wu JQ, Saksena MM, Soriano V, Vispo E, Saksena NK.

Virol J. 2015 Jan 27;12:4. doi: 10.1186/s12985-014-0236-6.


Regulation of gene expression by microRNA in HCV infection and HCV-mediated hepatocellular carcinoma.

Gupta P, Cairns MJ, Saksena NK.

Virol J. 2014 Apr 1;11:64. doi: 10.1186/1743-422X-11-64. Review.


HIV Associated Neurocognitive Disorders.

Zhou L, Saksena NK.

Infect Dis Rep. 2013 Jun 6;5(Suppl 1):e8. doi: 10.4081/idr.2013.s1.e8. eCollection 2013 Jun 6. Review.


Special Issue on HIV/AIDS: Infectious Disease Reports.

Saksena NK, Dwyer DE, Zhao RY.

Infect Dis Rep. 2013 Jun 6;5(Suppl 1):e1. doi: 10.4081/idr.2013.s1.e1. eCollection 2013 Jun 6. No abstract available.


Genome-wide analysis of primary peripheral blood mononuclear cells from HIV + patients-pre-and post- HAART show immune activation and inflammation the main drivers of host gene expression.

da Conceicao VN, Dyer WB, Gandhi K, Gupta P, Saksena NK.

Mol Cell Ther. 2014 Apr 3;2:11. doi: 10.1186/2052-8426-2-11. eCollection 2014.


Transcriptome analysis of primary monocytes from HIV-positive patients with differential responses to antiretroviral therapy.

Wu JQ, Sassé TR, Saksena MM, Saksena NK.

Virol J. 2013 Dec 27;10:361. doi: 10.1186/1743-422X-10-361.


Longitudinal Analysis of CCR5 and CXCR4 Usage in a Cohort of Antiretroviral Therapy-Naïve Subjects with Progressive HIV-1 Subtype C Infection.

Jakobsen MR, Cashin K, Roche M, Sterjovski J, Ellett A, Borm K, Flynn J, Erikstrup C, Gouillou M, Gray LR, Saksena NK, Wang B, Purcell DF, Kallestrup P, Zinyama-Gutsire R, Gomo E, Ullum H, Ostergaard L, Lee B, Ramsland PA, Churchill MJ, Gorry PR.

PLoS One. 2013 Jun 18;8(6):e65950. doi: 10.1371/journal.pone.0065950. Print 2013.


Viruses and neurodegeneration.

Zhou L, Miranda-Saksena M, Saksena NK.

Virol J. 2013 May 31;10:172. doi: 10.1186/1743-422X-10-172. Review.


A parallel genome-wide mRNA and microRNA profiling of the frontal cortex of HIV patients with and without HIV-associated dementia shows the role of axon guidance and downstream pathways in HIV-mediated neurodegeneration.

Zhou L, Pupo GM, Gupta P, Liu B, Tran SL, Rahme R, Wang B, Rua R, Rizos H, Carroll A, Cairns MJ, Saksena NK.

BMC Genomics. 2012 Nov 28;13:677. doi: 10.1186/1471-2164-13-677.


Genome-wide analysis of primary CD4+ and CD8+ T cell transcriptomes shows evidence for a network of enriched pathways associated with HIV disease.

Wu JQ, Dwyer DE, Dyer WB, Yang YH, Wang B, Saksena NK.

Retrovirology. 2011 Mar 16;8:18. doi: 10.1186/1742-4690-8-18.


Hierarchical kernel mixture models for the prediction of AIDS disease progression using HIV structural gp120 profiles.

Yoo PD, Shwen Ho Y, Ng J, Charleston M, Saksena NK, Yang P, Zomaya AY.

BMC Genomics. 2010 Dec 2;11 Suppl 4:S22. doi: 10.1186/1471-2164-11-S4-S22.


First evidence of overlaps between HIV-Associated Dementia (HAD) and non-viral neurodegenerative diseases: proteomic analysis of the frontal cortex from HIV+ patients with and without dementia.

Zhou L, Diefenbach E, Crossett B, Tran SL, Ng T, Rizos H, Rua R, Wang B, Kapur A, Gandhi K, Brew BJ, Saksena NK.

Mol Neurodegener. 2010 Jun 24;5:27. doi: 10.1186/1750-1326-5-27.


HIV reservoirs in vivo and new strategies for possible eradication of HIV from the reservoir sites.

Saksena NK, Wang B, Zhou L, Soedjono M, Ho YS, Conceicao V.

HIV AIDS (Auckl). 2010;2:103-22. Epub 2010 Jun 15.


Evidence for predilection of macrophage infiltration patterns in the deeper midline and mesial temporal structures of the brain uniquely in patients with HIV-associated dementia.

Zhou L, Rua R, Ng T, Vongrad V, Ho YS, Geczy C, Hsu K, Brew BJ, Saksena NK.

BMC Infect Dis. 2009 Dec 2;9:192. doi: 10.1186/1471-2334-9-192.


HIV-1 integrase polymorphisms are associated with prior antiretroviral drug exposure.

van Hal SJ, Herring B, Deris Z, Wang B, Saksena NK, Dwyer DE.

Retrovirology. 2009 Feb 9;6:12. doi: 10.1186/1742-4690-6-12.


Mechanisms of HIV non-progression; robust and sustained CD4+ T-cell proliferative responses to p24 antigen correlate with control of viraemia and lack of disease progression after long-term transfusion-acquired HIV-1 infection.

Dyer WB, Zaunders JJ, Yuan FF, Wang B, Learmont JC, Geczy AF, Saksena NK, McPhee DA, Gorry PR, Sullivan JS.

Retrovirology. 2008 Dec 11;5:112. doi: 10.1186/1742-4690-5-112.


Transitory viremic surges in a human immunodeficiency virus-positive elite controller can shift the cellular transcriptome profile: a word of caution for microarray studies.

Wu JQ, Wang B, Saksena NK.

J Virol. 2008 Oct;82(20):10326-7. doi: 10.1128/JVI.01386-08. Epub 2008 Aug 13. No abstract available.

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