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Items: 1 to 20 of 97


Modeling effects of voltage dependent properties of the cardiac muscarinic receptor on human sinus node function.

Moss R, Sachse FB, Moreno-Galindo EG, Navarro-Polanco RA, Tristani-Firouzi M, Seemann G.

PLoS Comput Biol. 2018 Oct 10;14(10):e1006438. doi: 10.1371/journal.pcbi.1006438. eCollection 2018 Oct.


Confocal Microscopy-Based Estimation of Parameters for Computational Modeling of Electrical Conduction in the Normal and Infarcted Heart.

Greiner J, Sankarankutty AC, Seemann G, Seidel T, Sachse FB.

Front Physiol. 2018 Apr 4;9:239. doi: 10.3389/fphys.2018.00239. eCollection 2018.


Catheterized Fiber-Optics Confocal Microscopy of the Beating Heart In Situ.

Huang C, Wasmund S, Hitchcock R, Marrouche NF, Sachse FB.

Circ Cardiovasc Imaging. 2017 Oct;10(10). pii: e006881. doi: 10.1161/CIRCIMAGING.117.006881. No abstract available.


Remodeling of the transverse tubular system after myocardial infarction in rabbit correlates with local fibrosis: A potential role of biomechanics.

Seidel T, Sankarankutty AC, Sachse FB.

Prog Biophys Mol Biol. 2017 Nov;130(Pt B):302-314. doi: 10.1016/j.pbiomolbio.2017.07.006. Epub 2017 Jul 11.


Physiological and pathophysiological role of transient receptor potential canonical channels in cardiac myocytes.

Ahmad AA, Streiff M, Hunter C, Hu Q, Sachse FB.

Prog Biophys Mol Biol. 2017 Nov;130(Pt B):254-263. doi: 10.1016/j.pbiomolbio.2017.06.005. Epub 2017 Jun 16. Review.


No fuzzy space for intracellular Na+ in healthy ventricular myocytes.

Sachse FB, Clark R, Giles WR.

J Gen Physiol. 2017 Jul 3;149(7):683-687. doi: 10.1085/jgp.201711826. Epub 2017 Jun 16. No abstract available.


Modulation of Asymmetric Flux in Heterotypic Gap Junctions by Pore Shape, Particle Size and Charge.

Mondal A, Sachse FB, Moreno AP.

Front Physiol. 2017 Apr 6;8:206. doi: 10.3389/fphys.2017.00206. eCollection 2017.


Sheet-Like Remodeling of the Transverse Tubular System in Human Heart Failure Impairs Excitation-Contraction Coupling and Functional Recovery by Mechanical Unloading.

Seidel T, Navankasattusas S, Ahmad A, Diakos NA, Xu WD, Tristani-Firouzi M, Bonios MJ, Taleb I, Li DY, Selzman CH, Drakos SG, Sachse FB.

Circulation. 2017 Apr 25;135(17):1632-1645. doi: 10.1161/CIRCULATIONAHA.116.024470. Epub 2017 Jan 10.


Computational simulations of asymmetric fluxes of large molecules through gap junction channel pores.

Mondal A, Appadurai DA, Akoum NW, Sachse FB, Moreno AP.

J Theor Biol. 2017 Jan 7;412:61-73. doi: 10.1016/j.jtbi.2016.08.040. Epub 2016 Aug 31.


Ginsenoside Rg3, a Gating Modifier of EAG Family K+ Channels.

Wu W, Gardner A, Sachse FB, Sanguinetti MC.

Mol Pharmacol. 2016 Oct;90(4):469-82. doi: 10.1124/mol.116.104091. Epub 2016 Aug 8.


Diffusion tensor imaging and histology of developing hearts.

Abdullah OM, Seidel T, Dahl M, Gomez AD, Yiep G, Cortino J, Sachse FB, Albertine KH, Hsu EW.

NMR Biomed. 2016 Oct;29(10):1338-49. doi: 10.1002/nbm.3576. Epub 2016 Aug 3.


Increased Susceptibility to Atrial Fibrillation Secondary to Atrial Fibrosis in Transgenic Goats Expressing Transforming Growth Factor-β1.

Polejaeva IA, Ranjan R, Davies CJ, Regouski M, Hall J, Olsen AL, Meng Q, Rutigliano HM, Dosdall DJ, Angel NA, Sachse FB, Seidel T, Thomas AJ, Stott R, Panter KE, Lee PM, Van Wettere AJ, Stevens JR, Wang Z, MacLeod RS, Marrouche NF, White KL.

J Cardiovasc Electrophysiol. 2016 Oct;27(10):1220-1229. doi: 10.1111/jce.13049. Epub 2016 Aug 30.


Cellular electrophysiological principles that modulate secretion from synovial fibroblasts.

Clark RB, Schmidt TA, Sachse FB, Boyle D, Firestein GS, Giles WR.

J Physiol. 2017 Feb 1;595(3):635-645. doi: 10.1113/JP270209. Epub 2017 Jan 5. Review.


Measurement of Strain in Cardiac Myocytes at Micrometer Scale Based on Rapid Scanning Confocal Microscopy and Non-Rigid Image Registration.

Lichter J, Li H, Sachse FB.

Ann Biomed Eng. 2016 Oct;44(10):3020-3031. doi: 10.1007/s10439-016-1593-7. Epub 2016 Mar 21.


Sensitivity and Specificity of Cardiac Tissue Discrimination Using Fiber-Optics Confocal Microscopy.

Huang C, Sachse FB, Hitchcock RW, Kaza AK.

PLoS One. 2016 Jan 25;11(1):e0147667. doi: 10.1371/journal.pone.0147667. eCollection 2016.


Analyzing Remodeling of Cardiac Tissue: A Comprehensive Approach Based on Confocal Microscopy and 3D Reconstructions.

Seidel T, Edelmann JC, Sachse FB.

Ann Biomed Eng. 2016 May;44(5):1436-1448. doi: 10.1007/s10439-015-1465-6. Epub 2015 Sep 23.


Cardiac Resynchronization Therapy Reduces Subcellular Heterogeneity of Ryanodine Receptors, T-Tubules, and Ca2+ Sparks Produced by Dyssynchronous Heart Failure.

Li H, Lichter JG, Seidel T, Tomaselli GF, Bridge JH, Sachse FB.

Circ Heart Fail. 2015 Nov;8(6):1105-14. doi: 10.1161/CIRCHEARTFAILURE.115.002352. Epub 2015 Aug 20.


Reply: does size matter? In search of a physiological definition of myocardial atrophy.

Diakos NA, Selzman CH, Stehlik J, Sachse FB, Kfoury AG, Koliopoulou A, McKellar S, Fang JC, Li DY, Drakos SG.

J Am Coll Cardiol. 2015 May 19;65(19):2156-7. doi: 10.1016/j.jacc.2015.02.064. No abstract available.


Gain-of-function mutations in the calcium channel CACNA1C (Cav1.2) cause non-syndromic long-QT but not Timothy syndrome.

Wemhöner K, Friedrich C, Stallmeyer B, Coffey AJ, Grace A, Zumhagen S, Seebohm G, Ortiz-Bonnin B, Rinné S, Sachse FB, Schulze-Bahr E, Decher N.

J Mol Cell Cardiol. 2015 Mar;80:186-95. doi: 10.1016/j.yjmcc.2015.01.002. Epub 2015 Jan 26.


Local delivery of fluorescent dye for fiber-optics confocal microscopy of the living heart.

Huang C, Kaza AK, Hitchcock RW, Sachse FB.

Front Physiol. 2014 Sep 25;5:367. doi: 10.3389/fphys.2014.00367. eCollection 2014.

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