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Items: 1 to 20 of 21


Endothelial Mesenchymal Transition in Hypoxic Microvascular Endothelial Cells and Paracrine Induction of Cardiomyocyte Apoptosis Are Mediated via TGFβ₁/SMAD Signaling.

Sniegon I, Prieß M, Heger J, Schulz R, Euler G.

Int J Mol Sci. 2017 Oct 31;18(11). pii: E2290. doi: 10.3390/ijms18112290.


Cyclooxygenase-2 promotes pulmonary intravascular macrophage accumulation by exacerbating BMP signaling in rat experimental hepatopulmonary syndrome.

Liu C, Gao J, Chen B, Chen L, Belguise K, Yu W, Lu K, Wang X, Yi B.

Biochem Pharmacol. 2017 Aug 15;138:205-215. doi: 10.1016/j.bcp.2017.06.117. Epub 2017 Jun 19.


Activation of CD137 Signaling Promotes Angiogenesis in Atherosclerosis via Modulating Endothelial Smad1/5-NFATc1 Pathway.

Weng J, Wang C, Zhong W, Li B, Wang Z, Shao C, Chen Y, Yan J.

J Am Heart Assoc. 2017 Mar 13;6(3). pii: e004756. doi: 10.1161/JAHA.116.004756.


A fucoidan from Nemacystus decipiens disrupts angiogenesis through targeting bone morphogenetic protein 4.

Wang W, Chen H, Zhang L, Qin Y, Cong Q, Wang P, Ding K.

Carbohydr Polym. 2016 Jun 25;144:305-14. doi: 10.1016/j.carbpol.2016.02.068. Epub 2016 Feb 26.


Tetramethylpyrazine inhibits tumor growth of lung cancer through disrupting angiogenesis via BMP/Smad/Id-1 signaling.

Jia Y, Wang Z, Zang A, Jiao S, Chen S, Fu Y.

Int J Oncol. 2016 May;48(5):2079-86. doi: 10.3892/ijo.2016.3443. Epub 2016 Mar 15.


BMPR2 gene delivery reduces mutation-related PAH and counteracts TGF-β-mediated pulmonary cell signalling.

Feng F, Harper RL, Reynolds PN.

Respirology. 2016 Apr;21(3):526-32. doi: 10.1111/resp.12712. Epub 2015 Dec 21.


Mitomycin-Induced Pulmonary Veno-Occlusive Disease: Evidence From Human Disease and Animal Models.

Perros F, Günther S, Ranchoux B, Godinas L, Antigny F, Chaumais MC, Dorfmüller P, Hautefort A, Raymond N, Savale L, Jaïs X, Girerd B, Cottin V, Sitbon O, Simonneau G, Humbert M, Montani D.

Circulation. 2015 Sep 1;132(9):834-47. doi: 10.1161/CIRCULATIONAHA.115.014207. Epub 2015 Jun 30.


Bone morphogenic protein-2 regulates the myogenic differentiation of PMVECs in CBDL rat serum-induced pulmonary microvascular remodeling.

Liu C, Chen L, Zeng J, Cui J, Ning JN, Wang GS, Belguise K, Wang X, Qian GS, Lu KZ, Yi B.

Exp Cell Res. 2015 Aug 1;336(1):109-18. doi: 10.1016/j.yexcr.2015.05.025. Epub 2015 Jun 10.


BAMBI elimination enhances alternative TGF-β signaling and glomerular dysfunction in diabetic mice.

Fan Y, Li X, Xiao W, Fu J, Harris RC, Lindenmeyer M, Cohen CD, Guillot N, Baron MH, Wang N, Lee K, He JC, Schlondorff D, Chuang PY.

Diabetes. 2015 Jun;64(6):2220-33. doi: 10.2337/db14-1397. Epub 2015 Jan 9.


Inactivation of Vhl in osteochondral progenitor cells causes high bone mass phenotype and protects against age-related bone loss in adult mice.

Weng T, Xie Y, Huang J, Luo F, Yi L, He Q, Chen D, Chen L.

J Bone Miner Res. 2014 Apr;29(4):820-9. doi: 10.1002/jbmr.2087.


Desmoglein-2-integrin Beta-8 interaction regulates actin assembly in endothelial cells: deregulation in systemic sclerosis.

Giusti B, Margheri F, Rossi L, Lapini I, Magi A, Serratì S, Chillà A, Laurenzana A, Magnelli L, Calorini L, Bianchini F, Fibbi G, Abbate R, Del Rosso M.

PLoS One. 2013 Jul 11;8(7):e68117. doi: 10.1371/journal.pone.0068117. Print 2013. Erratum in: PLoS One. 2013;8(7). doi:10.1371/annotation/b41766f2-c23d-455e-8d6e-e4bce5ae1d80.


Endothelial cells in co-culture enhance embryonic stem cell differentiation to pancreatic progenitors and insulin-producing cells through BMP signaling.

Talavera-Adame D, Wu G, He Y, Ng TT, Gupta A, Kurtovic S, Hwang JY, Farkas DL, Dafoe DC.

Stem Cell Rev. 2011 Sep;7(3):532-43. doi: 10.1007/s12015-011-9232-z.


Transforming growth factor-beta1 causes pulmonary microvascular endothelial cell apoptosis via ALK5.

Lu Q, Patel B, Harrington EO, Rounds S.

Am J Physiol Lung Cell Mol Physiol. 2009 May;296(5):L825-38. doi: 10.1152/ajplung.90307.2008. Epub 2009 Mar 6.


Ionizing radiation shifts the PAI-1/ID-1 balance and activates notch signaling in endothelial cells.

Scharpfenecker M, Kruse JJ, Sprong D, Russell NS, Ten Dijke P, Stewart FA.

Int J Radiat Oncol Biol Phys. 2009 Feb 1;73(2):506-13. doi: 10.1016/j.ijrobp.2008.09.052.


Effects of bone morphogenic proteins and transforming growth factor-beta on In-vitro production of endothelin-1 by human pulmonary microvascular endothelial cells.

Star GP, Giovinazzo M, Langleben D.

Vascul Pharmacol. 2009 Jan-Feb;50(1-2):45-50. doi: 10.1016/j.vph.2008.09.001. Epub 2008 Sep 24.


Bone morphogenetic protein-9 is a circulating vascular quiescence factor.

David L, Mallet C, Keramidas M, Lamandé N, Gasc JM, Dupuis-Girod S, Plauchu H, Feige JJ, Bailly S.

Circ Res. 2008 Apr 25;102(8):914-22. doi: 10.1161/CIRCRESAHA.107.165530. Epub 2008 Feb 28.


Functional characterization of bone morphogenetic protein binding sites and Smad1/5 activation in human vascular cells.

Upton PD, Long L, Trembath RC, Morrell NW.

Mol Pharmacol. 2008 Feb;73(2):539-52. Epub 2007 Nov 7.


Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells.

David L, Mallet C, Mazerbourg S, Feige JJ, Bailly S.

Blood. 2007 Mar 1;109(5):1953-61. Epub 2006 Oct 26.


ALK1 signalling analysis identifies angiogenesis related genes and reveals disparity between TGF-beta and constitutively active receptor induced gene expression.

Lux A, Salway F, Dressman HK, Kröner-Lux G, Hafner M, Day PJ, Marchuk DA, Garland J.

BMC Cardiovasc Disord. 2006 Apr 4;6:13.

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