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Pediatr Blood Cancer. 2013 May;60(5):719-27. doi: 10.1002/pbc.24468. Epub 2013 Jan 17.

SIOP-PODC recommendations for graduated-intensity treatment of retinoblastoma in developing countries.

Author information

1
Hospital de Pediatria SAMIC Prof Dr Juan P Garrahan, Buenos Aires, Argentina. gchantada@yahoo.com

Abstract

Retinoblastoma remains incurable in many regions of the world. The major obstacles to cure are delayed diagnosis, poor treatment compliance, and lack of evidence-based recommendations for clinical management. Although enucleation is curative for intraocular disease, in developing countries retinoblastoma is often diagnosed after the disease has disseminated beyond the eye. A SIOP-PODC committee generated guidelines for the clinical management of retinoblastoma in developing countries and developed a classification system based on the resources available in those settings. Recommendations are provided for staging and treatment of unilateral and bilateral retinoblastoma and counseling of families for whom compliance is an issue.

PMID:
23335388
DOI:
10.1002/pbc.24468
[Indexed for MEDLINE]

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