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Items: 1 to 20 of 43

1.

Loss of foxo rescues stem cell aging in Drosophila germ line.

Artoni F, Kreipke RE, Palmeira O, Dixon C, Goldberg Z, Ruohola-Baker H.

Elife. 2017 Sep 19;6. pii: e27842. doi: 10.7554/eLife.27842.

2.

First critical repressive H3K27me3 marks in embryonic stem cells identified using designed protein inhibitor.

Moody JD, Levy S, Mathieu J, Xing Y, Kim W, Dong C, Tempel W, Robitaille AM, Dang LT, Ferreccio A, Detraux D, Sidhu S, Zhu L, Carter L, Xu C, Valensisi C, Wang Y, Hawkins RD, Min J, Moon RT, Orkin SH, Baker D, Ruohola-Baker H.

Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):10125-10130. doi: 10.1073/pnas.1706907114. Epub 2017 Sep 1.

3.

Metabolic remodeling during the loss and acquisition of pluripotency.

Mathieu J, Ruohola-Baker H.

Development. 2017 Feb 15;144(4):541-551. doi: 10.1242/dev.128389. Review.

4.

WNT/β-catenin signaling regulates mitochondrial activity to alter the oncogenic potential of melanoma in a PTEN-dependent manner.

Brown K, Yang P, Salvador D, Kulikauskas R, Ruohola-Baker H, Robitaille AM, Chien AJ, Moon RT, Sherwood V.

Oncogene. 2017 Jun 1;36(22):3119-3136. doi: 10.1038/onc.2016.450. Epub 2017 Jan 16.

5.

Wnt/β-catenin signaling promotes self-renewal and inhibits the primed state transition in naïve human embryonic stem cells.

Xu Z, Robitaille AM, Berndt JD, Davidson KC, Fischer KA, Mathieu J, Potter JC, Ruohola-Baker H, Moon RT.

Proc Natl Acad Sci U S A. 2016 Oct 18;113(42):E6382-E6390. Epub 2016 Oct 3.

6.

Metabolic remodeling in early development and cardiomyocyte maturation.

Ellen Kreipke R, Wang Y, Miklas JW, Mathieu J, Ruohola-Baker H.

Semin Cell Dev Biol. 2016 Apr;52:84-92. doi: 10.1016/j.semcdb.2016.02.004. Epub 2016 Feb 18. Review.

7.

The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition.

Sperber H, Mathieu J, Wang Y, Ferreccio A, Hesson J, Xu Z, Fischer KA, Devi A, Detraux D, Gu H, Battle SL, Showalter M, Valensisi C, Bielas JH, Ericson NG, Margaretha L, Robitaille AM, Margineantu D, Fiehn O, Hockenbery D, Blau CA, Raftery D, Margolin AA, Hawkins RD, Moon RT, Ware CB, Ruohola-Baker H.

Nat Cell Biol. 2015 Dec;17(12):1523-35. doi: 10.1038/ncb3264. Epub 2015 Nov 16.

8.

Let-7 family of microRNA is required for maturation and adult-like metabolism in stem cell-derived cardiomyocytes.

Kuppusamy KT, Jones DC, Sperber H, Madan A, Fischer KA, Rodriguez ML, Pabon L, Zhu WZ, Tulloch NL, Yang X, Sniadecki NJ, Laflamme MA, Ruzzo WL, Murry CE, Ruohola-Baker H.

Proc Natl Acad Sci U S A. 2015 May 26;112(21):E2785-94. doi: 10.1073/pnas.1424042112. Epub 2015 May 11.

9.

Tie-mediated signal from apoptotic cells protects stem cells in Drosophila melanogaster.

Xing Y, Su TT, Ruohola-Baker H.

Nat Commun. 2015 May 11;6:7058. doi: 10.1038/ncomms8058.

10.

Tri-iodo-l-thyronine promotes the maturation of human cardiomyocytes-derived from induced pluripotent stem cells.

Yang X, Rodriguez M, Pabon L, Fischer KA, Reinecke H, Regnier M, Sniadecki NJ, Ruohola-Baker H, Murry CE.

J Mol Cell Cardiol. 2014 Jul;72:296-304. doi: 10.1016/j.yjmcc.2014.04.005. Epub 2014 Apr 13.

11.

miRNA sensitivity to Drosha levels correlates with pre-miRNA secondary structure.

Sperber H, Beem A, Shannon S, Jones R, Banik P, Chen Y, Ku S, Varani G, Yao S, Ruohola-Baker H.

RNA. 2014 May;20(5):621-31. doi: 10.1261/rna.043943.113. Epub 2014 Mar 27.

12.

Hypoxia-inducible factors have distinct and stage-specific roles during reprogramming of human cells to pluripotency.

Mathieu J, Zhou W, Xing Y, Sperber H, Ferreccio A, Agoston Z, Kuppusamy KT, Moon RT, Ruohola-Baker H.

Cell Stem Cell. 2014 May 1;14(5):592-605. doi: 10.1016/j.stem.2014.02.012. Epub 2014 Mar 20.

13.

Derivation of naive human embryonic stem cells.

Ware CB, Nelson AM, Mecham B, Hesson J, Zhou W, Jonlin EC, Jimenez-Caliani AJ, Deng X, Cavanaugh C, Cook S, Tesar PJ, Okada J, Margaretha L, Sperber H, Choi M, Blau CA, Treuting PM, Hawkins RD, Cirulli V, Ruohola-Baker H.

Proc Natl Acad Sci U S A. 2014 Mar 25;111(12):4484-9. doi: 10.1073/pnas.1319738111. Epub 2014 Mar 12.

14.

Dystrophin-deficient cardiomyocytes derived from human urine: new biologic reagents for drug discovery.

Guan X, Mack DL, Moreno CM, Strande JL, Mathieu J, Shi Y, Markert CD, Wang Z, Liu G, Lawlor MW, Moorefield EC, Jones TN, Fugate JA, Furth ME, Murry CE, Ruohola-Baker H, Zhang Y, Santana LF, Childers MK.

Stem Cell Res. 2014 Mar;12(2):467-80. doi: 10.1016/j.scr.2013.12.004. Epub 2013 Dec 23.

15.

Molecular mechanism of sphingosine-1-phosphate action in Duchenne muscular dystrophy.

Nguyen-Tran DH, Hait NC, Sperber H, Qi J, Fischer K, Ieronimakis N, Pantoja M, Hays A, Allegood J, Reyes M, Spiegel S, Ruohola-Baker H.

Dis Model Mech. 2014 Jan;7(1):41-54. doi: 10.1242/dmm.013631. Epub 2013 Sep 25.

16.

Increased sphingosine-1-phosphate improves muscle regeneration in acutely injured mdx mice.

Ieronimakis N, Pantoja M, Hays AL, Dosey TL, Qi J, Fischer KA, Hoofnagle AN, Sadilek M, Chamberlain JS, Ruohola-Baker H, Reyes M.

Skelet Muscle. 2013 Aug 1;3(1):20. doi: 10.1186/2044-5040-3-20.

17.

Hypoxia induces re-entry of committed cells into pluripotency.

Mathieu J, Zhang Z, Nelson A, Lamba DA, Reh TA, Ware C, Ruohola-Baker H.

Stem Cells. 2013 Sep;31(9):1737-48. doi: 10.1002/stem.1446.

18.

Regulation of stem cell populations by microRNAs.

Mathieu J, Ruohola-Baker H.

Adv Exp Med Biol. 2013;786:329-51. doi: 10.1007/978-94-007-6621-1_18. Review.

19.

MicroRNA regulation and role in stem cell maintenance, cardiac differentiation and hypertrophy.

Kuppusamy KT, Sperber H, Ruohola-Baker H.

Curr Mol Med. 2013 Jun;13(5):757-64. Review.

20.

Use of somatic mutations to quantify random contributions to mouse development.

Zhou W, Tan Y, Anderson DJ, Crist EM, Ruohola-Baker H, Salipante SJ, Horwitz MS.

BMC Genomics. 2013 Jan 18;14:39. doi: 10.1186/1471-2164-14-39.

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