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Secretory products from epicardial adipose tissue from patients with type 2 diabetes impair mitochondrial β-oxidation in cardiomyocytes via activation of the cardiac renin-angiotensin system and induction of miR-208a.

Blumensatt M, Fahlbusch P, Hilgers R, Bekaert M, Herzfeld de Wiza D, Akhyari P, Ruige JB, Ouwens DM.

Basic Res Cardiol. 2017 Jan;112(1):2. Epub 2016 Nov 18.


Children's psychosocial stress and emotional eating: A role for leptin?

Michels N, Sioen I, Ruige J, De Henauw S.

Int J Eat Disord. 2017 May;50(5):471-480. doi: 10.1002/eat.22593. Epub 2016 Jul 21.


Relationship between glycaemic variability and hyperglycaemic clamp-derived functional variables in (impending) type 1 diabetes.

Van Dalem A, Demeester S, Balti EV, Decochez K, Weets I, Vandemeulebroucke E, Van de Velde U, Walgraeve A, Seret N, De Block C, Ruige J, Gillard P, Keymeulen B, Pipeleers DG, Gorus FK; Belgian Diabetes Registry.

Diabetologia. 2015 Dec;58(12):2753-64. doi: 10.1007/s00125-015-3761-y. Epub 2015 Sep 26.


Determinants of testosterone levels in human male obesity.

Bekaert M, Van Nieuwenhove Y, Calders P, Cuvelier CA, Batens AH, Kaufman JM, Ouwens DM, Ruige JB.

Endocrine. 2015 Sep;50(1):202-11. doi: 10.1007/s12020-015-0563-4. Epub 2015 Mar 13.


Fear of hypoglycaemia in adults with Type 1 diabetes: results from Diabetes MILES - The Netherlands.

Nefs G, Bevelander S, Hendrieckx C, Bot M, Ruige J, Speight J, Pouwer F.

Diabet Med. 2015 Oct;32(10):1289-96. doi: 10.1111/dme.12739. Epub 2015 Mar 28.


Dietary restriction and exercise for diabetic patients with chronic kidney disease: a systematic review.

Van Huffel L, Tomson CR, Ruige J, Nistor I, Van Biesen W, Bolignano D.

PLoS One. 2014 Nov 25;9(11):e113667. doi: 10.1371/journal.pone.0113667. eCollection 2014. Review.


Hyperglycemic clamp and oral glucose tolerance test for 3-year prediction of clinical onset in persistently autoantibody-positive offspring and siblings of type 1 diabetic patients.

Balti EV, Vandemeulebroucke E, Weets I, Van De Velde U, Van Dalem A, Demeester S, Verhaeghen K, Gillard P, De Block C, Ruige J, Keymeulen B, Pipeleers DG, Decochez K, Gorus FK; Belgian Diabetes Registry.

J Clin Endocrinol Metab. 2015 Feb;100(2):551-60. doi: 10.1210/jc.2014-2035. Epub 2014 Nov 18.


Moxifloxacin dosing in post-bariatric surgery patients.

Colin P, Eleveld DJ, Struys MM, T'Jollyn H, Bortel LM, Ruige J, De Waele J, Van Bocxlaer J, Boussery K.

Br J Clin Pharmacol. 2014 Jul;78(1):84-93. doi: 10.1111/bcp.12302.


Activin A is associated with impaired myocardial glucose metabolism and left ventricular remodeling in patients with uncomplicated type 2 diabetes.

Chen WJ, Greulich S, van der Meer RW, Rijzewijk LJ, Lamb HJ, de Roos A, Smit JW, Romijn JA, Ruige JB, Lammertsma AA, Lubberink M, Diamant M, Ouwens DM.

Cardiovasc Diabetol. 2013 Oct 17;12:150. doi: 10.1186/1475-2840-12-150.


Beneficial and adverse effects of testosterone on the cardiovascular system in men.

Ruige JB, Ouwens DM, Kaufman JM.

J Clin Endocrinol Metab. 2013 Nov;98(11):4300-10. doi: 10.1210/jc.2013-1970. Epub 2013 Sep 24.


The influence of sprint interval training on body composition, physical and metabolic fitness in adolescents and young adults with intellectual disability: a randomized controlled trial.

Boer PH, Meeus M, Terblanche E, Rombaut L, Wandele ID, Hermans L, Gysel T, Ruige J, Calders P.

Clin Rehabil. 2014 Mar;28(3):221-31. doi: 10.1177/0269215513498609. Epub 2013 Aug 20.


Activin A impairs insulin action in cardiomyocytes via up-regulation of miR-143.

Blumensatt M, Greulich S, Herzfeld de Wiza D, Mueller H, Maxhera B, Rabelink MJ, Hoeben RC, Akhyari P, Al-Hasani H, Ruige JB, Ouwens DM.

Cardiovasc Res. 2013 Nov 1;100(2):201-10. doi: 10.1093/cvr/cvt173. Epub 2013 Jun 28.


The relationship between changes in steps/day and health outcomes after a pedometer-based physical activity intervention with telephone support in type 2 diabetes patients.

Van Dyck D, De Greef K, Deforche B, Ruige J, Bouckaert J, Tudor-Locke CE, Kaufman JM, De Bourdeaudhuij I.

Health Educ Res. 2013 Jun;28(3):539-45. doi: 10.1093/her/cyt038. Epub 2013 Mar 14.


Secretory products from epicardial adipose tissue of patients with type 2 diabetes mellitus induce cardiomyocyte dysfunction.

Greulich S, Maxhera B, Vandenplas G, de Wiza DH, Smiris K, Mueller H, Heinrichs J, Blumensatt M, Cuvelier C, Akhyari P, Ruige JB, Ouwens DM, Eckel J.

Circulation. 2012 Nov 6;126(19):2324-34. doi: 10.1161/CIRCULATIONAHA.111.039586. Epub 2012 Oct 12.


Glucose intolerance and the amount of visceral adipose tissue contribute to an increase in circulating triglyceride concentrations in Caucasian obese females.

Berings M, Wehlou C, Verrijken A, Deschepper E, Mertens I, Kaufman JM, Van Gaal LF, Ouwens DM, Ruige JB.

PLoS One. 2012;7(9):e45145. doi: 10.1371/journal.pone.0045145. Epub 2012 Sep 28.


Endogenous oestradiol and cardiovascular disease in healthy men: a systematic review and meta-analysis of prospective studies.

Vandenplas G, De Bacquer D, Calders P, Fiers T, Kaufman JM, Ouwens DM, Ruige JB.

Heart. 2012 Oct;98(20):1478-82. Epub 2012 Jun 26. Review.


Sex steroid-induced changes in circulating monocyte chemoattractant protein-1 levels may contribute to metabolic dysfunction in obese men.

Ruige JB, Bekaert M, Lapauw B, Fiers T, Lehr S, Hartwig S, Herzfeld de Wiza D, Schiller M, Passlack W, Van Nieuwenhove Y, Pattyn P, Cuvelier C, Taes YE, Sell H, Eckel J, Kaufman JM, Ouwens DM.

J Clin Endocrinol Metab. 2012 Jul;97(7):E1187-91. doi: 10.1210/jc.2011-3069. Epub 2012 Apr 20.


Chemerin as biomarker for insulin sensitivity in males without typical characteristics of metabolic syndrome.

Ouwens DM, Bekaert M, Lapauw B, Van Nieuwenhove Y, Lehr S, Hartwig S, Calders P, Kaufman JM, Sell H, Eckel J, Ruige JB.

Arch Physiol Biochem. 2012 Jul;118(3):135-8. doi: 10.3109/13813455.2012.654800. Epub 2012 Feb 15.


Heat shock protein 60 as a mediator of adipose tissue inflammation and insulin resistance.

Märker T, Sell H, Zillessen P, Glöde A, Kriebel J, Ouwens DM, Pattyn P, Ruige J, Famulla S, Roden M, Eckel J, Habich C.

Diabetes. 2012 Mar;61(3):615-25. doi: 10.2337/db10-1574. Epub 2012 Feb 7.


Combined gene and protein expression of hormone-sensitive lipase and adipose triglyceride lipase, mitochondrial content, and adipocyte size in subcutaneous and visceral adipose tissue of morbidly obese men.

De Naeyer H, Ouwens DM, Van Nieuwenhove Y, Pattyn P, 't Hart LM, Kaufman JM, Sell H, Eckel J, Cuvelier C, Taes YE, Ruige JB.

Obes Facts. 2011;4(5):407-16. doi: 10.1159/000333445. Epub 2011 Oct 14.

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