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Items: 1 to 20 of 148

1.

Dynamin inhibitors block activation of mTORC1 by amino acids independently of dynamin.

Persaud A, Cormerais Y, Pouyssegur J, Rotin D.

J Cell Sci. 2018 Jan 4;131(1). pii: jcs211755. doi: 10.1242/jcs.211755.

PMID:
29150487
2.

Inhaled ENaC antisense oligonucleotide ameliorates cystic fibrosis-like lung disease in mice.

Crosby JR, Zhao C, Jiang C, Bai D, Katz M, Greenlee S, Kawabe H, McCaleb M, Rotin D, Guo S, Monia BP.

J Cyst Fibros. 2017 Nov;16(6):671-680. doi: 10.1016/j.jcf.2017.05.003. Epub 2017 May 20.

PMID:
28539224
3.

[All-Russian Consensus on Diagnosis and Treatment of Celiac Disease in Children and Adults].

Parfenov AI, Bykova SV, Sabel'nikova EA, Maev IV, Baranov AA, Bakulin IG, Krums LM, Bel'mer SV, Borovik TE, Zakharova IN, Dmitrieva YA, Roslavtseva EA, Kornienko EA, Khavkin AI, Potapov AS, Revnova MO, Mukhina YG, Shcherbakov PL, Fedorov ED, Belousova EA, Khalif IL, Khomeriki SG, Rotin DL, Vorob'eva NG, Pivnik AV, Gudkova RB, Chernin VV, Vokhmyanina NV, Pukhlikova TV, Degtyarev DA, Damulin IV, Mkrtumyan AM, Dzhulai GS, Tetruashvili NK, Baranovsky AY, Nazarenko LI, Kharitonov AG, Loranskaya ID, Saifutdinov RG, Livzan MA, Abramov DA, Osipenko MF, Oreshko LV, Tkachenko EI, Sitkin SI, Efremov LI.

Ter Arkh. 2017;89(3):94-107. doi: 10.17116/terarkh201789394-107. Russian.

PMID:
28378737
4.

[Diabetes mellitus and nonalcoholic fatty liver disease: The verges of contingency].

Bakulin IG, Sandler YG, Vinnitskaya EV, Keiyan VA, Rodionova SV, Rotin DL.

Ter Arkh. 2017;89(2):59-65. doi: 10.17116/terarkh201789259-65. Russian.

PMID:
28281517
5.

[Clinical and morphological characteristics, diagnostic criteria, and outcomes of surgical treatment of TSH-secreting pituitary adenomas].

Astaf'eva LI, Kadashev BA, Shishkina LV, Kalinin PL, Fomichev DV, Kutin MA, Aref'eva IA, Dzeranova LK, Sidneva YG, Klochkova IS, Rotin DL.

Zh Vopr Neirokhir Im N N Burdenko. 2016;80(6):24-35. doi: 10.17116/neiro201680624-35. English, Russian.

6.

The Ubiquitin Ligase Nedd4L Regulates the Na/K/2Cl Co-transporter NKCC1/SLC12A2 in the Colon.

Jiang C, Kawabe H, Rotin D.

J Biol Chem. 2017 Feb 24;292(8):3137-3145. doi: 10.1074/jbc.M116.770065. Epub 2017 Jan 13.

7.

Ubiquitylation-dependent oligomerization regulates activity of Nedd4 ligases.

Attali I, Tobelaim WS, Persaud A, Motamedchaboki K, Simpson-Lavy KJ, Mashahreh B, Levin-Kravets O, Keren-Kaplan T, Pilzer I, Kupiec M, Wiener R, Wolf DA, Rotin D, Prag G.

EMBO J. 2017 Feb 15;36(4):425-440. doi: 10.15252/embj.201694314. Epub 2017 Jan 9.

8.

Intestinal knockout of Nedd4 enhances growth of Apcmin tumors.

Lu C, Thoeni C, Connor A, Kawabe H, Gallinger S, Rotin D.

Oncogene. 2016 Nov 10;35(45):5839-5849. doi: 10.1038/onc.2016.125. Epub 2016 Apr 18.

PMID:
27086928
9.

[Seronegative celiac disease: A case report].

Krums LM, Parfenov AI, Sabelnikova EA, Poleva NI, Bykova SV, Dubtsova EA, Gudkova RB, Khomeriki SG, Rotin DL, Pavlov MV, Starostina NS.

Ter Arkh. 2016;88(2):75-77. doi: 10.17116/terarkh201688275-77. Russian.

PMID:
27030188
10.

[A new non-invasive method for assessing steatosis in chronic liver diseases].

Bakulin IG, Sandler YG, Keyan VA, Rotin DL.

Ter Arkh. 2016;88(2):49-57. doi: 10.17116/terarkh201688249-57. Russian.

PMID:
27030184
11.

System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.

Zhang W, Wu KP, Sartori MA, Kamadurai HB, Ordureau A, Jiang C, Mercredi PY, Murchie R, Hu J, Persaud A, Mukherjee M, Li N, Doye A, Walker JR, Sheng Y, Hao Z, Li Y, Brown KR, Lemichez E, Chen J, Tong Y, Harper JW, Moffat J, Rotin D, Schulman BA, Sidhu SS.

Mol Cell. 2016 Apr 7;62(1):121-36. doi: 10.1016/j.molcel.2016.02.005. Epub 2016 Mar 3.

12.

Drosophila Nedd4-long reduces Amphiphysin levels in muscles and leads to impaired T-tubule formation.

Safi F, Shteiman-Kotler A, Zhong Y, Iliadi KG, Boulianne GL, Rotin D.

Mol Biol Cell. 2016 Mar 15;27(6):907-18. doi: 10.1091/mbc.E15-06-0420. Epub 2016 Jan 28.

13.

Thyrotropin-secreting pituitary adenoma in an 11-year-old boy with type 1 autoimmune polyglandular syndrome.

Mazerkina N, Trunin Y, Gorelyshev S, Golanov A, Kadashev B, Shishkina L, Rotin D, Karmanov M, Orlova E.

J Pediatr Endocrinol Metab. 2016 Feb;29(2):237-40. doi: 10.1515/jpem-2015-0018.

PMID:
26244671
14.

Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.

Cancer Genome Atlas Research Network, Brat DJ, Verhaak RG, Aldape KD, Yung WK, Salama SR, Cooper LA, Rheinbay E, Miller CR, Vitucci M, Morozova O, Robertson AG, Noushmehr H, Laird PW, Cherniack AD, Akbani R, Huse JT, Ciriello G, Poisson LM, Barnholtz-Sloan JS, Berger MS, Brennan C, Colen RR, Colman H, Flanders AE, Giannini C, Grifford M, Iavarone A, Jain R, Joseph I, Kim J, Kasaian K, Mikkelsen T, Murray BA, O'Neill BP, Pachter L, Parsons DW, Sougnez C, Sulman EP, Vandenberg SR, Van Meir EG, von Deimling A, Zhang H, Crain D, Lau K, Mallery D, Morris S, Paulauskis J, Penny R, Shelton T, Sherman M, Yena P, Black A, Bowen J, Dicostanzo K, Gastier-Foster J, Leraas KM, Lichtenberg TM, Pierson CR, Ramirez NC, Taylor C, Weaver S, Wise L, Zmuda E, Davidsen T, Demchok JA, Eley G, Ferguson ML, Hutter CM, Mills Shaw KR, Ozenberger BA, Sheth M, Sofia HJ, Tarnuzzer R, Wang Z, Yang L, Zenklusen JC, Ayala B, Baboud J, Chudamani S, Jensen MA, Liu J, Pihl T, Raman R, Wan Y, Wu Y, Ally A, Auman JT, Balasundaram M, Balu S, Baylin SB, Beroukhim R, Bootwalla MS, Bowlby R, Bristow CA, Brooks D, Butterfield Y, Carlsen R, Carter S, Chin L, Chu A, Chuah E, Cibulskis K, Clarke A, Coetzee SG, Dhalla N, Fennell T, Fisher S, Gabriel S, Getz G, Gibbs R, Guin R, Hadjipanayis A, Hayes DN, Hinoue T, Hoadley K, Holt RA, Hoyle AP, Jefferys SR, Jones S, Jones CD, Kucherlapati R, Lai PH, Lander E, Lee S, Lichtenstein L, Ma Y, Maglinte DT, Mahadeshwar HS, Marra MA, Mayo M, Meng S, Meyerson ML, Mieczkowski PA, Moore RA, Mose LE, Mungall AJ, Pantazi A, Parfenov M, Park PJ, Parker JS, Perou CM, Protopopov A, Ren X, Roach J, Sabedot TS, Schein J, Schumacher SE, Seidman JG, Seth S, Shen H, Simons JV, Sipahimalani P, Soloway MG, Song X, Sun H, Tabak B, Tam A, Tan D, Tang J, Thiessen N, Triche T Jr, Van Den Berg DJ, Veluvolu U, Waring S, Weisenberger DJ, Wilkerson MD, Wong T, Wu J, Xi L, Xu AW, Yang L, Zack TI, Zhang J, Aksoy BA, Arachchi H, Benz C, Bernard B, Carlin D, Cho J, DiCara D, Frazer S, Fuller GN, Gao J, Gehlenborg N, Haussler D, Heiman DI, Iype L, Jacobsen A, Ju Z, Katzman S, Kim H, Knijnenburg T, Kreisberg RB, Lawrence MS, Lee W, Leinonen K, Lin P, Ling S, Liu W, Liu Y, Liu Y, Lu Y, Mills G, Ng S, Noble MS, Paull E, Rao A, Reynolds S, Saksena G, Sanborn Z, Sander C, Schultz N, Senbabaoglu Y, Shen R, Shmulevich I, Sinha R, Stuart J, Sumer SO, Sun Y, Tasman N, Taylor BS, Voet D, Weinhold N, Weinstein JN, Yang D, Yoshihara K, Zheng S, Zhang W, Zou L, Abel T, Sadeghi S, Cohen ML, Eschbacher J, Hattab EM, Raghunathan A, Schniederjan MJ, Aziz D, Barnett G, Barrett W, Bigner DD, Boice L, Brewer C, Calatozzolo C, Campos B, Carlotti CG Jr, Chan TA, Cuppini L, Curley E, Cuzzubbo S, Devine K, DiMeco F, Duell R, Elder JB, Fehrenbach A, Finocchiaro G, Friedman W, Fulop J, Gardner J, Hermes B, Herold-Mende C, Jungk C, Kendler A, Lehman NL, Lipp E, Liu O, Mandt R, McGraw M, Mclendon R, McPherson C, Neder L, Nguyen P, Noss A, Nunziata R, Ostrom QT, Palmer C, Perin A, Pollo B, Potapov A, Potapova O, Rathmell WK, Rotin D, Scarpace L, Schilero C, Senecal K, Shimmel K, Shurkhay V, Sifri S, Singh R, Sloan AE, Smolenski K, Staugaitis SM, Steele R, Thorne L, Tirapelli DP, Unterberg A, Vallurupalli M, Wang Y, Warnick R, Williams F, Wolinsky Y, Bell S, Rosenberg M, Stewart C, Huang F, Grimsby JL, Radenbaugh AJ, Zhang J.

N Engl J Med. 2015 Jun 25;372(26):2481-98. doi: 10.1056/NEJMoa1402121. Epub 2015 Jun 10.

15.

LAPTM4b recruits the LAT1-4F2hc Leu transporter to lysosomes and promotes mTORC1 activation.

Milkereit R, Persaud A, Vanoaica L, Guetg A, Verrey F, Rotin D.

Nat Commun. 2015 May 22;6:7250. doi: 10.1038/ncomms8250.

16.

RNA Interference Screen to Identify Kinases That Suppress Rescue of ΔF508-CFTR.

Trzcińska-Daneluti AM, Chen A, Nguyen L, Murchie R, Jiang C, Moffat J, Pelletier L, Rotin D.

Mol Cell Proteomics. 2015 Jun;14(6):1569-83. doi: 10.1074/mcp.M114.046375. Epub 2015 Mar 29.

17.

Rsp5/Nedd4 is the main ubiquitin ligase that targets cytosolic misfolded proteins following heat stress.

Fang NN, Chan GT, Zhu M, Comyn SA, Persaud A, Deshaies RJ, Rotin D, Gsponer J, Mayor T.

Nat Cell Biol. 2014 Dec;16(12):1227-37. doi: 10.1038/ncb3054. Epub 2014 Oct 26.

18.

Tyrosine phosphorylation of NEDD4 activates its ubiquitin ligase activity.

Persaud A, Alberts P, Mari S, Tong J, Murchie R, Maspero E, Safi F, Moran MF, Polo S, Rotin D.

Sci Signal. 2014 Oct 7;7(346):ra95. doi: 10.1126/scisignal.2005290.

PMID:
25292214
19.

Ubiquitin E3 ligase Nedd4-1 acts as a downstream target of PI3K/PTEN-mTORC1 signaling to promote neurite growth.

Hsia HE, Kumar R, Luca R, Takeda M, Courchet J, Nakashima J, Wu S, Goebbels S, An W, Eickholt BJ, Polleux F, Rotin D, Wu H, Rossner MJ, Bagni C, Rhee JS, Brose N, Kawabe H.

Proc Natl Acad Sci U S A. 2014 Sep 9;111(36):13205-10. doi: 10.1073/pnas.1400737111. Epub 2014 Aug 25.

20.

Comprehensive molecular profiling of lung adenocarcinoma.

Cancer Genome Atlas Research Network.

Nature. 2014 Jul 31;511(7511):543-50. doi: 10.1038/nature13385. Epub 2014 Jul 9. Erratum in: Nature. 2014 Oct 9;514(7521):262. Rogers, K [corrected to Rodgers, K].

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