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Items: 1 to 20 of 31


Fungal-derived cues promote ocular autoimmunity through a Dectin-2/Card9-mediated mechanism.

Brown BR, Lee EJ, Snow PE, Vance EE, Iwakura Y, Ohno N, Miura N, Lin X, Brown GD, Wells CA, Smith JR, Caspi RR, Rosenzweig HL.

Clin Exp Immunol. 2017 Aug 1. doi: 10.1111/cei.13021. [Epub ahead of print]


Mincle Activation and the Syk/Card9 Signaling Axis Are Central to the Development of Autoimmune Disease of the Eye.

Lee EJ, Brown BR, Vance EE, Snow PE, Silver PB, Heinrichs D, Lin X, Iwakura Y, Wells CA, Caspi RR, Rosenzweig HL.

J Immunol. 2016 Apr 1;196(7):3148-58. doi: 10.4049/jimmunol.1502355. Epub 2016 Feb 26.


Investigation of the relationship between the onset of arthritis and uveitis in genetically predisposed SKG mice.

Lee EJ, Vance EE, Brown BR, Snow PS, Clowers JS, Sakaguchi S, Rosenzweig HL.

Arthritis Res Ther. 2015 Aug 19;17:218. doi: 10.1186/s13075-015-0725-z.


Aberrant interleukin-1 signalling does not increase susceptibility of mice to NOD2-dependent uveitis.

Lee EJ, Allensworth JJ, Clowers JS, Rosenzweig HL.

Clin Exp Ophthalmol. 2015 May-Jun;43(4):349-57. doi: 10.1111/ceo.12438. Epub 2014 Oct 30.


Investigation of the peptidoglycan sensing molecule, PGLYRP-2, in murine inflammatory uveitis.

Clowers JS, Allensworth JJ, Lee EJ, Rosenzweig HL.

Br J Ophthalmol. 2013 Apr;97(4):504-10. doi: 10.1136/bjophthalmol-2012-302650. Epub 2013 Jan 29.


Spondyloarthritis: the eyes have it: uveitis in patients with spondyloarthritis.

Rosenbaum JT, Rosenzweig HL.

Nat Rev Rheumatol. 2012 Apr 3;8(5):249-50. doi: 10.1038/nrrheum.2012.43. No abstract available.


Neutralization of IL-17 ameliorates uveitis but damages photoreceptors in a murine model of spondyloarthritis.

Kezic JM, Glant TT, Rosenbaum JT, Rosenzweig HL.

Arthritis Res Ther. 2012 Jan 23;14(1):R18. doi: 10.1186/ar3697.


Impact of IL-1 signalling on experimental uveitis and arthritis.

Planck SR, Woods A, Clowers JS, Nicklin MJ, Rosenbaum JT, Rosenzweig HL.

Ann Rheum Dis. 2012 May;71(5):753-60. doi: 10.1136/annrheumdis-2011-200556. Epub 2012 Jan 20.


Interplay between innate and adaptive immunity in the development of non-infectious uveitis.

Willermain F, Rosenbaum JT, Bodaghi B, Rosenzweig HL, Childers S, Behrend T, Wildner G, Dick AD.

Prog Retin Eye Res. 2012 Mar;31(2):182-94. doi: 10.1016/j.preteyeres.2011.11.004. Epub 2011 Nov 22. Review.


The NLRP3 inflammasome is active but not essential in endotoxin-induced uveitis.

Rosenzweig HL, Woods A, Clowers JS, Planck SR, Rosenbaum JT.

Inflamm Res. 2012 Mar;61(3):225-31. doi: 10.1007/s00011-011-0404-8. Epub 2011 Nov 26.


Interferon-γ regulates discordant mechanisms of uveitis versus joint and axial disease in a murine model resembling spondylarthritis.

Kezic JM, Davey MP, Glant TT, Rosenbaum JT, Rosenzweig HL.

Arthritis Rheum. 2012 Mar;64(3):762-71. doi: 10.1002/art.33404.


Investigation of the differential potentials of TLR agonists to elicit uveitis in mice.

Allensworth JJ, Planck SR, Rosenbaum JT, Rosenzweig HL.

J Leukoc Biol. 2011 Dec;90(6):1159-66. doi: 10.1189/jlb.0511249. Epub 2011 Sep 20.


NLRs in immune privileged sites.

Rosenzweig HL, Planck SR, Rosenbaum JT.

Curr Opin Pharmacol. 2011 Aug;11(4):423-8. doi: 10.1016/j.coph.2011.07.002. Epub 2011 Jul 29. Review.


Contrasting ocular effects of local versus systemic endotoxin.

Rosenbaum JT, Woods A, Kezic J, Planck SR, Rosenzweig HL.

Invest Ophthalmol Vis Sci. 2011 Aug 17;52(9):6472-7. doi: 10.1167/iovs.11-7742.


Endotoxin-induced uveitis is primarily dependent on radiation-resistant cells and on MyD88 but not TRIF.

Kezic J, Taylor S, Gupta S, Planck SR, Rosenzweig HL, Rosenbaum JT.

J Leukoc Biol. 2011 Aug;90(2):305-11. doi: 10.1189/jlb.0111036. Epub 2011 May 24.


Dectin-1 and NOD2 mediate cathepsin activation in zymosan-induced arthritis in mice.

Rosenzweig HL, Clowers JS, Nunez G, Rosenbaum JT, Davey MP.

Inflamm Res. 2011 Jul;60(7):705-14. doi: 10.1007/s00011-011-0324-7. Epub 2011 Mar 20.


NOD2 deficiency results in increased susceptibility to peptidoglycan-induced uveitis in mice.

Rosenzweig HL, Galster K, Vance EE, Ensign-Lewis J, Nunez G, Davey MP, Rosenbaum JT.

Invest Ophthalmol Vis Sci. 2011 Jun 9;52(7):4106-12. doi: 10.1167/iovs.10-6263.


Nucleotide-binding oligomerization domain 2 and Toll-like receptor 2 function independently in a murine model of arthritis triggered by intraarticular peptidoglycan.

Rosenzweig HL, Jann MJ, Vance EE, Planck SR, Rosenbaum JT, Davey MP.

Arthritis Rheum. 2010 Apr;62(4):1051-9. doi: 10.1002/art.27335.


Nucleotide oligomerization domain-2 interacts with 2'-5'-oligoadenylate synthetase type 2 and enhances RNase-L function in THP-1 cells.

Dugan JW, Albor A, David L, Fowlkes J, Blackledge MT, Martin TM, Planck SR, Rosenzweig HL, Rosenbaum JT, Davey MP.

Mol Immunol. 2009 Dec;47(2-3):560-6. doi: 10.1016/j.molimm.2009.09.025. Epub 2009 Oct 23.


BALB/c mice genetically susceptible to proteoglycan-induced arthritis and spondylitis show colony-dependent differences in disease penetrance.

Farkas B, Boldizsar F, Tarjanyi O, Laszlo A, Lin SM, Hutas G, Tryniszewska B, Mangold A, Nagyeri G, Rosenzweig HL, Finnegan A, Mikecz K, Glant TT.

Arthritis Res Ther. 2009;11(1):R21. doi: 10.1186/ar2613. Epub 2009 Feb 16.

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